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dibutyryl cyclic AMP An analogue of cyclic AMP that shares some of the pharmacological effects of this nucleotide, but is generally believed to enter cells more readily on account of its greater hydrophobicity.
(18 Nov 1997)
dibutyryl cyclic GMP <chemical> N-(1-oxobutyl)-cyclic 3',5'-(hydrogen phosphate)-2'-butanoate guanosine. A derivative of cyclic GMP. It has a higher resistance to extracellular and intracellular phosphodiesterase than cyclic GMP.
Chemical name: Guanosine, N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate
(12 Dec 1998)
DNA-binding protein, cyclic AMP-responsive A protein that has been shown to function as a calcium regulated transcription factor as well as a substrate for depolarisation-activated calcium calmodulin-dependent protein kinases I and II. This protein functions to integrate both calcium and camp signals.
(12 Dec 1998)
inositol cyclic 1,2-phosphate 1-phosphodiesterase <enzyme> Converts inositol 1:2-cyclic phosphate to inositol 2-phosphate; do not confuse with inositol 1,2 cyclic-phosphate 2-phosphohydrolase see annexin III
Registry number: EC 3.1.4.-
Synonym: cins(1,2)p hydrolase II
(26 Jun 1999)
ethers, cyclic Compounds of the general formula r-o-r arranged in a ring or crown formation.
(12 Dec 1998)
2',3'-cyclic nucleotide 2'-phosphodiesterase <enzyme> Catalyses the hydrolysis of the 2'-phosphodiesterase bond to yield nucleoside 3'phosphate
Registry number: EC 3.1.4.16
Synonym: 2',3'-cyclic nucleotide 2'-phosphohydrolase
(26 Jun 1999)
2',3'-cyclic nucleotide 3'-phosphodiesterase <enzyme> Catalyses the hydrolysis of the 3'-phosphoesterase bond to yield nucleoside 2'-phosphate
Registry number: EC 3.1.4.37
Synonym: 2',3'-cyclic nucleotide 3'-phosphohydrolase, 2',3'-cn phosphodiesterase, 2',3'-cnpase
(26 Jun 1999)
2',3'-cyclic-nucleotide phosphodiesterases <enzyme> Nucleoside-2',3'-cyclic phosphate nucleotidohydrolase. Enzymes that catalyze the hydrolysis of the 2'- or 3'- phosphate bonds of 2',3'-cyclic nucleotides. Also hydrolyzes nucleoside monophosphates.
Registry number: EC 3.1.4.-
(12 Dec 1998)
3',5'-cyclic AMP synthetase <enzyme> Enzyme responsible for the ATP.
(06 May 1997)
3',5'-cyclic-GMP phosphodiesterase <enzyme> An enzyme that catalyses the hydrolysis of cyclic GMP to yield guanosine-5'-phosphate.
Chemical name: 3',5'-Cyclic-GMP 5'-nucleotidohydrolase
Registry number: EC 3.1.4.35
(12 Dec 1998)
3',5'-cyclic-nucleotide phosphodiesterase <enzyme> An enzyme that catalyses the hydrolysis of cyclic AMP to form adenosine 5'-phosphate. The enzyme is widely distributed in animal tissue and controls the level of intracellular cyclic AMP. Also acts on 3',5'-cyclic imp and 3',5'-cyclic GMP.
Chemical name: 3',5'-Cyclic-nucleotide 5'-nucleotidohydrolase
Registry number: EC 3.1.4.17
(12 Dec 1998)
8-bromo cyclic adenosine monophosphate <chemical> 8-bromoadenosine cyclic 3',5'-(hydrogen phosphate). A long-acting derivative of cyclic AMP. It is an activator of cyclic AMP-dependent protein kinase, but resistant to degradation by cyclic AMP phosphodiesterase.
Chemical name: Adenosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate)
(12 Dec 1998)
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