methacholine (메타콜린
| dose-escalation | A preliminary clinical trial in which the amount of the drug is either periodically increased or increased with each new trial arm that is added. Used to determine how a drug is tolerated in people. (09 Oct 1997) |
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| dose fractionation | Adminstration of the total dose of radiation (radiation dosage) in parts, at timed intervals. (12 Dec 1998) |
| dose intensity | In chemotherapy, the total amount of drug delivered in a one-week period. Can be given all at once or over a period of several days. (16 Dec 1997) |
| dose-ranging | A preliminary clinical trial in which the amount of the drug is either periodically increased or increased with each new trial arm that is added. Used to determine how a drug is tolerated in people. (09 Oct 1997) |
| dose-response curve | This is a graph to show the relation between the dose of a drug or other chemical and the degree of response it produces, as measured by the percentage of the exposed population showing a defined, often quantal, effect. (09 Oct 1997) |
| dose-response relationship | Relationship in which a change in the amount, intensity, or duration of exposure is associated with a change in risk of a specified outcome. (05 Mar 2000) |
| dose-response relationship, drug | The relationship between the dose of an administered drug and the response of the organism to the drug. (12 Dec 1998) |
| dose-response relationship, immunologic | A specific immune response elicited by a specific dose of an immunologically active substance or cell in an organism, tissue, or cell. (12 Dec 1998) |
| dose-response relationship, radiation | The relationship between the dose of administered radiation and the response of the organism or tissue to the radiation. (12 Dec 1998) |
| immunologic high dose tolerance | Induction of tolerance by exposure to large amounts of protein antigens. (05 Mar 2000) |
| initial dose | A comparatively large dose given at the beginning of treatment to get the patient under the influence of the drug. Synonym: loading dose. (05 Mar 2000) |
| integral dose | The total energy absorbed by the body, the product of the mass of tissue irradiated and the absorbed dose; unit, the gram rad. (05 Mar 2000) |
| optimum dose | The dose of a drug or radiation that will produce the desired effect with minimum likelihood of undesirable symptoms. (05 Mar 2000) |
| therapeutic dose | The quantity of any substance required to effect the cure of a disease or that will correct the manifestations of a deficiency of a particular factor in the diet, effective dose used with therapeutically applied compounds. Synonym: therapeutic dose. (05 Mar 2000) |
| tissue culture infectious dose | The quantity of a cytopathogenic agent, such as a virus, that will produce a cytopathic effect in 50% of the cultures inoculated. (05 Mar 2000) |