| interstitial lung disease | <chest medicine> A group of lung disorders which result in scarring and dysfunction of the alveolus (air sac) in the lung. This results in poor oxygen diffusion from the air into the bloodstream. Widespread inflammation in the lung leads to fibrosis (scarring). Causes include chronic exposure to organic and inorganic dusts, fumes, vapors, radiation, medications and certain lung infections. Examples include asbestosis, silicosis, coal worker's pneumoconiosis and diffuse interstitial fibrosis. Smoking increases the risk in all cases. (27 Sep 1997) |
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| interstitial lung disease with increased volume | <radiology> Cystic fibrosis (CF), eosinophilic granuloma (EG), lymphangioleiomyomatosis (LAM) (12 Dec 1998) |
| interstitial mastitis | Inflammation of the connective tissue of the mammary gland. (05 Mar 2000) |
| interstitial myositis | Induration of a muscle through an interstitial growth of fibrous tissue. Synonym: Froriep's induration, interstitial myositis, myofascitis. (05 Mar 2000) |
| interstitial nephritis | <nephrology> A relatively uncommon condition which is characterised by inflammation of the renal tubules, glomeruli and surrounding tissue. Interstitial nephritis is usually be temporary and often associated with the use of a particular medication. Chronic and progressive forms do exist. Drugs that have been associated with interstitial nephritis include penicillins, ampicillin, sulpha drugs, non-steroidal anti-inflammatory agents, furosemide and thiazide diuretics. May result in mild kidney dysfunction or acute renal failure. Treatment may be with corticosteroids. Incidence: 1 in 25,000. (27 Sep 1997) |
| interstitial neuritis | Inflammation of the connective tissue framework of a nerve. Synonym: Eichhorst's neuritis. (05 Mar 2000) |
| interstitial nucleus | A group of widely spaced, medium-sized neurons in the dorsomedial region of the upper mesencephalic tegmentum, immediately lateral to the nucleus of Darkschewitsch; together with the latter, the interstitial nucleus is closely associated with the medial longitudinal fasciculus, via which it receives fibres from the vestibular nuclei and projects crossed fibres via the posterior commissure to the oculomotor nucleus; also projects fibres to all spinal levels. It is believed to be involved in the integration of head and eye movements, particularly eye movements of a vertical or oblique nature. Synonym: nucleus interstitialis, interstitial nucleus of Cajal. (05 Mar 2000) |
| interstitial nucleus of Cajal | A group of widely spaced, medium-sized neurons in the dorsomedial region of the upper mesencephalic tegmentum, immediately lateral to the nucleus of Darkschewitsch; together with the latter, the interstitial nucleus is closely associated with the medial longitudinal fasciculus, via which it receives fibres from the vestibular nuclei and projects crossed fibres via the posterior commissure to the oculomotor nucleus; also projects fibres to all spinal levels. It is believed to be involved in the integration of head and eye movements, particularly eye movements of a vertical or oblique nature. Synonym: nucleus interstitialis, interstitial nucleus of Cajal. (05 Mar 2000) |
| interstitial pattern | One of several chest radiographic patterns associated with interstitial infiltration or thickening, including honeycomb pattern, miliary pattern, reticulonodular pattern, or septal lines. (05 Mar 2000) |
| interstitial plasma cell pneumonia | <chest medicine> A pneumonia caused by an infection with Pneumocystis carinii. Pneumocystis carinii grows rapidly in the lungs of patients with immunosuppression, particularly due to AIDS and is the leading AIDS-related cause of death. Pneumocystis carinii infection sometimes may occur elsewhere in the body (skin, eye, spleen, liver or heart). It is considered one of the diagnostic criteria for AIDS in an HIV positive individual. (10 Jan 1998) |
| interstitial pneumonia | <chest medicine> A form of pneumonia which involves the interstitial tissues (connective tissue) of the lung. Causes are varied and include: infection with Pneumocystis carinii, radiation exposure, toxic inhalation, viral pneumonias and giant cell pneumonia. (27 Sep 1997) |
| interstitial pneumonitis | <chest medicine, pathology> A form if pneumonia which involves the interstitial tissues (connective tissue) of the lung. Causes are varied and include: infection with Pneumocystis carinii, radiation exposure, toxic inhalation, viral pneumonias and giant cell pneumonia. (27 Sep 1997) |
| interstitial pregnancy | Development of the fertilised ovum in the uterine portion of the fallopian tube. Synonym: interstitial pregnancy, tubouterine pregnancy. (05 Mar 2000) |
| interstitial pulmonary fibrosis | <radiology> Idiopathic, idiopathic pulmonary fibrosis (AKA: usual interstitial pneumonitis), Hamman-Rich syndrome (rapidly progressive), drug-related, collagen-vascular disease, rheumatoid lung disease, scleroderma (12 Dec 1998) |
| interstitial radiation | Radiation therapy in which a radioactive material is placed directly into a tumour. (12 Dec 1998) |