| cell-mediated l. |
a variation of the mixed lymphocyte culture (MLC) that is a functional test of the ability of cytotoxic T lymphocytes to kill target cells. Lymphocytes from two individuals are cultured together for several days, one population having been prevented from proliferating by treatment with radiation or mitomycin (a “one-way” MLC); they are then cultured for several hours with 51Cr-labeled target cells that are HLA-identical to the stimulator cells. Cytotoxicity is measured as percentage of 51Cr released from specific target cells compared to percentage of 51Cr released from control (nonspecific target) cells.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| cell-mediated lympholysis a. |
(CML assay) see under lympholysis.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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