| myocardial necrosis | Irreversible destruction of myocardial (heart muscle) cells. (27 Sep 1997) |
|---|---|
| postpartum pituitary necrosis syndrome | <syndrome> Hypopituitarism arising from a severe circulatory collapse postpartum, with resultant pituitary necrosis. Synonym: postpartum pituitary necrosis syndrome, thyrohypophysial syndrome. (05 Mar 2000) |
| cystic medial necrosis | Loss of elastic and muscle fibres in the aortic media, with accumulation of mucopolysaccharide, sometimes in cystlike spaces between the fibres; a disease of unknown cause, which may be inherited and which predisposes to dissecting aneurysms. Synonym: Erdheim disease, medionecrosis aortae idiopathica cystica, medionecrosis of the aorta, mucoid medial degeneration. (05 Mar 2000) |
| progressive emphysematous necrosis | <microbiology> A severe form of gangrene (tissue necrosis) caused by Clostridium infection. Also referred to as necrotising subcutaneous infection. Results in death of the subcutaneous tissues and muscle layers. See: necrotising fascitis. (27 Sep 1997) |
| hepatic necrosis | A severe and rapidly progressive form of hepatitis accompanied by hepatocellular death and the signs and symptoms of hepatic failure. May be a complication of hepatitis B, C or D. (27 Sep 1997) |
| simple necrosis | A stage of coagulation necrosis; the occurrence of a coarsely granular or hyaline change in the cytoplasm, and the lack of a recognizable nucleus, with the general configuration of the dead cells being relatively unchanged. (05 Mar 2000) |
| necrosis | <pathology> The sum of the morphological changes indicative of cell death and caused by the progressive degradative action of enzymes, it may affect groups of cells or part of a structure or an organ. Origin: Gr. Nekrosis = deadness (18 Nov 1997) |
| necrosis bacillus | A species of gram-negative, non-spore-forming bacteria isolated from the natural cavities of man and other animals and from necrotic lesions, abscesses, and blood. (12 Dec 1998) |
| subcutaneous fat necrosis of newborn | Indurated plaques and nodules appearing usually a few days or a few weeks after birth and usually resolving within a few months, characterised microscopically by birefringent needle-shaped crystals within necrotic fat cells; the condition remains localised, unlike sclerema neonatorum. (05 Mar 2000) |
| suppurative necrosis | Liquefactive necrosis with pus formation. (05 Mar 2000) |
| dental pulp necrosis | Death of pulp tissue. When the necrosis is due to ischemia with superimposed bacterial infection, it is referred to as pulp gangrene. (12 Dec 1998) |
| ischemic necrosis | Necrosis caused by hypoxia resulting from local deprivation of blood supply, as by infarction. (05 Mar 2000) |
| total necrosis | Complete necrosis of the cytologic and histologic elements in a portion of tissue, as in caseous necrosis, death of an entire organ or part. (05 Mar 2000) |
| epiphysial aseptic necrosis | Aseptic necrosis of bony epiphyses, probably due to ischemia; it may affect the upper end of the femur (Legg-Calve-Perthes disease), the tibial tubercle (Osgood-Schlatter disease), the tarsal navicular bone or the patella (Kohler's disease), the second metatarsal head (Freiberg's disease), vertebral bodies (Scheuermann's disease), or the capitellum of the humerus (Panner's disease). (05 Mar 2000) |
| tumor necrosis factor | <cytokine> Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin. Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine. Synonym: cachectin. Acronym: TNF (13 Nov 1997) |