| bone marrow neoplasms | Neoplasms located in the bone marrow. They are differentiated from neoplasms composed of bone marrow cells, such as myeloma. most bone marrow neoplasms are metastatic. (12 Dec 1998) |
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| bone marrow purging | Techniques for the removal of subpopulations of cells (usually residual tumour cells) from the bone marrow ex vivo before it is infused. The purging is achieved by a variety of agents including pharmacologic agents, biophysical agents (laser photoirradiation or radioisotopes) and immunologic agents. Bone marrow purging is used in both autologous and allogeneic bone marrow transplantation. (12 Dec 1998) |
| bone marrow suppression | <oncology, pharmacology> A side effect of many anticancer and antiviral drugs, including AZT. Bone marrow suppression leads to a decrease in white blood cells, red blood cells and platelets. Such reductions in turn result in anaemia, bacterial infections and spontaneous or excess bleeding. (09 Oct 1997) |
| bone marrow transplant | <procedure> A procedure in which a section of bone marrow is taken from one person and transplanted into another. It is used to replace bone marrow that has been damaged or diseased. It can be a treatment option in leukaemia. Acronym: BMT (16 Dec 1997) |
| bone marrow transplantation | <oncology, procedure> Treatment in which healthy bone marrow replaces bone marrow that has been affected by a disease or by treatment for a disease. Acronym: BMT (12 May 1997) |
| bone matrix | The intercellular substance of bone tissue consisting of collagen fibres, ground substance, and inorganic bone salts. (05 Mar 2000) |
| bone metastases | <radiology> Sensitivity . . . . . . . . . . . . . . . . . . . . . . . . . 98%, False negatives: multiple myeloma, thyroid carcinoma, small, purely lytic lesions, oat cell carcinoma Specificity . . . . . . . . . . . . . . . . . . . . . . . . High, False positives: Paget's disease, arthritis, fibrous dysplasia, infection, trauma, new or old REF: MacNeil BJ. Value of bone scanning in neoplastic disease. Semin Nucl Med 14:277, 1984. (12 Dec 1998) |
| bone metastases in kids | <radiology> Rhabdomyosarcoma, neuroblastoma, histiocytosis X Note: Wilms tumour goes to lung, not bone (12 Dec 1998) |
| bone morphogenetic protein | <protein> Activity derived from bone that induces the formation of cartilage and bone in vivo. Seven bone morphogenetic proteins have been described, BMP 1 being the only one not in the TGF beta superfamily. BMP 3 was formerly called osteogenin. Acronym: BMP (18 Nov 1997) |
| bone morphogenetic proteins | Non-collagenous factors, believed to be proteins, that occur in demineralised bone and stimulate osteogenesis. They can induce new bone formation in ectopic sites and thus have potential use in bone repair. (12 Dec 1998) |
| bone nails | Rods of bone, metal, or other material used for fixation of the fragments or ends of fractured bones. (12 Dec 1998) |
| bone phosphate | Ca3(PO4)2;used as an antacid. Synonym: bone ash, bone phosphate, tertiary calcium phosphate, tricalcium phosphate, whitlockite. (05 Mar 2000) |
| bone plate | A metal bar with perforations for the insertion of screws; used to immobilise fractured segments. (05 Mar 2000) |
| bone plates | Metal bars with perforations for the insertion of screws, used to immobilise fractured segments. (12 Dec 1998) |
| bone reflex | A reflex excited by a stimulus applied to a bone. (05 Mar 2000) |
| capitate bone | Enlarged or swollen at tip, gathered into a mass at apex, as compound stigma, a knoblike stigma terminating a style. (09 Oct 1997) |
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| vaginal process of sphenoid bone | A thin lamina of bone that extends medially under the body of the sphenoid bone from the medial lamina of the pterygoid process; it articulates with the vomer and the palatine bone. Synonym: processus vaginalis ossis sphenoidalis, sheath process of sphenoid bone. (05 Mar 2000) |
| palatine bone | An irregularly shaped bone posterior to the maxilla, which enters into the formation of the nasal cavity, the orbit, and the hard palate; it articulates with the maxilla, inferior nasal concha, sphenoid, and ethmoid bones, the vomer and its fellow of the opposite side. Synonym: os palatinum. (05 Mar 2000) |
| palatine surface of horizontal plate of palatine bone | The inferior surface of the horizontal plate of the palatine bone. Synonym: facies palatina laminae horizontalis ossis palatini. (05 Mar 2000) |
| malar bone | A quadrilateral bone which forms the prominence of the cheek; it articulates with the frontal, sphenoid, temporal, and maxillary bone. Synonym: os zygomaticum, cheek bone, jugal bone, mala, malar bone, os malare, yoke bone, zygoma. (05 Mar 2000) |
| marble bone disease | The formation of abnormally dense bone, as opposed to osteoporosis. (18 Nov 1997) |
| marginal tubercle of zygomatic bone | A prominence on the temporal border of the zygomatic bone to which the temporal fascia is attached. Synonym: tuberculum marginale ossis zygomatici, marginal tubercle. (05 Mar 2000) |
| Recklinghausen's disease of bone | Rarefying osteitis with fibrous degeneration and formation of cysts, and with the presence of fibrous nodules on the affected bones. It is due to marked osteoclastic activity secondary to hyperfunction of the parathyroid glands. (12 Dec 1998) |
| parietal bone | The side bone of the skull. (12 Dec 1998) |
| parietal border of frontal bone | The margin of the frontal bone that articulates with the parietal bone. Synonym: margo parietalis ossis frontalis. (05 Mar 2000) |
| parietal border of sphenoid bone | The margin of the greater wing of the sphenoid that articulates with the parietal bone. Synonym: margo parietalis ossis sphenoidalis. (05 Mar 2000) |
| parietal border of temporal bone | The border of the squamous part of the temporal bone that articulates with the parietal bone. Synonym: margo parietalis ossis temporalis. (05 Mar 2000) |
| Vesalius' bone | The tuberosity of the fifth metatarsal bone sometimes existing as a separate bone. Synonym: vesalianum, Vesalius' bone. (05 Mar 2000) |
| cartilage bone | A bone that develops in a cartilage environment after the latter is partially or entirely destroyed by calcification and subsequent resorption. Synonym: cartilage bone, replacement bone. (05 Mar 2000) |
| giant cell tumour of bone | A bone tumour composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumours range from benign to frankly malignant lesions. The tumour occurs most frequently in an end of a long tubular bone in young adults. (12 Dec 1998) |