| Stilling's gelatinous substance | The central gray matter of the spinal cord surrounding the central canal. Synonym: substantia intermedia centralis et lateralis, anterior gray column, Stilling's gelatinous substance, substantia gelatinosa centralis. (05 Mar 2000) |
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| neurosecretory substance | The secretion of nerve cell bodies located in the hypothalamus; the substance is transported by way of hypothalamo-hypophysial tract fibres into the neurohypophysis where the terminals of the nerve fibres contain the secretion. As seen in the fibres and terminals with a light microscope, the substance appears as Herring bodies or hyaline bodies of the pituitary (see under body). See: hyaline bodies of pituitary. (05 Mar 2000) |
| Nissl substance | The material consisting of granular endoplasmic reticulum and ribosomes that occurs in nerve cell bodies and dendrites. Synonym: basophil substance, basophilic substance, chromophil substance, Nissl bodies, Nissl granules, substantia basophilia, tigroid bodies, tigroid substance. (05 Mar 2000) |
| substance | The material constituting an organ or body, also called substantia. Origin: L. Substantia (18 Nov 1997) |
| substance abuse | Maladaptive pattern of drug or alcohol use that may lead to social, occupational, psychological, or physical problems. (05 Mar 2000) |
| substance abuse detection | Detection of drugs that have been abused, overused, or misused, including legal and illegal drugs. Urine screening is the usual method of detection. (12 Dec 1998) |
| substance abuse disorders | A class of mental disorders in which behavioural and biological changes are associated with regular use of alcohol, drugs, and related substances that affect the central nervous system and personal and social functioning. (05 Mar 2000) |
| substance abuse, intravenous | Abuse, overuse, or misuse of a substance by its injection into a vein. (12 Dec 1998) |
| substance abuse treatment centres | Health facilities providing therapy and/or rehabilitation for substance-dependent individuals. Methadone distribution centres are included. (12 Dec 1998) |
| substance dependence | A pattern of behavioural, physiologic, and cognitive symptoms that develop due to substance use or abuse; usually indicated by tolerance to the effects of the substance and withdrawal symptoms that develop when use of the substance is terminated. (05 Mar 2000) |
| substance-induced organic mental disorders | Mental disorders caused by use of drugs, e.g., cocaine. (05 Mar 2000) |
| substance of lens of eye | That which constitutes the lens of the eye, composed of a nucleus and a cortex and covered by an epithelium. Synonym: substantia lentis. (05 Mar 2000) |
| substance P | A vasoactive intestinal peptide (1348 D) found in the brain, spinal ganglia and intestine of vertebrates. Induces vasodilatation, salivation and increases capillary permeability. Sequence: RPKPQFFGLM. (18 Nov 1997) |
| substance-related disorders | These non-psychotic disorders include those related to the taking of a drug of abuse (including alcohol), to the side effects of a medication, and to toxin exposure. (12 Dec 1998) |
| substance withdrawal syndrome | <syndrome> Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug. (12 Dec 1998) |