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specific immune globulin Globulin fraction of pooled serums (or plasma) selected for high titre of antibodies specific for a particular antigen, or from persons specifically immunised.
(05 Mar 2000)
immune serum globulin A sterile solution of globulin's that contains many antibodies normally present in adult human blood; a passive immunizing agent frequently used for prophylaxis against hepatitis A.
(05 Mar 2000)
testosterone-oestrogen-binding globulin A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Changes in its concentration significantly affect the ratio of unbound (biologically active) testosterone to estradiol in plasma.
(12 Dec 1998)
tetanus immune globulin <protein> A protein antibody to tetanus toxin, given as passive immunity for those lacking any prior tetanus vaccination.
(27 Sep 1997)
thyroid binding globulin <protein> Thyroid binding globulin (TBG) is a plasma protein which binds the majority of thyroid hormone in the bloodstream. Bound thyroid hormone is inactive, only the unbound fraction (0.3%) is considered active. Birth control pills and pregnancy can lead to increased TBG levels in the plasma. Androgens can decrease TBG levels in the plasma.
(27 Sep 1997)
thyroxine-binding globulin An alpha-globulin of blood with a strong binding affinity for thyroxine; triiodothyronine is bound to it much less firmly; a deficiency or excess of this protein may occur as a rare benign X-linked disorder.
Synonym: thyroxine-binding protein.
(05 Mar 2000)
zoster immune globulin A globulin fraction of pooled plasma from individuals who have recovered from herpes zoster; used prophylactically and therapeutically for varicella.
(05 Mar 2000)
acetyl-CoA:alpha-glucosaminide acetyltransferase <enzyme> An enzyme involved in the synthesis of certain carbohydrate moieties on proteins. A deficiency of this enzyme leads to mucopolysaccharidosis type III C.
(05 Mar 2000)
adrenergic alpha-agonists Drugs that selectively bind to and activate alpha adrenergic receptors.
(12 Dec 1998)
adrenergic alpha-antagonists Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
(12 Dec 1998)
alpha First letter of the Greek alphabet, a.
(05 Mar 2000)
alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase <enzyme> Incorporates n-acetyglucosamine as the third branch of complex n-glycosyl-oligosaccharide of hen oviduct
Registry number: EC 2.4.1.145
Synonym: glcnac-transferase iv, n-acetylglucosaminyltransferase iv, udp-glcnac-gngn(glcnac to man alpha1-3)beta 4-n-acetylglucosaminyltransferase iv
(26 Jun 1999)
alpha-1,4-glucan lyase <enzyme> Degrades alpha-1,4-glucan to produce 1,5-anhydrofructose; from seaweeds gracilariopsis lemaneiformis and gracilaria verrucosa; mw 111 kD; amino acid sequence has been determined
Registry number: EC 4.2.2.-
Synonym: alpha-1,4-glucan 4-lyase
(26 Jun 1999)
alpha 1-4-mannosyltransferase <enzyme> From mycobacterium smegmatis; involved in methylmannose polysaccharide elongation; GDP-mannose is donor
Registry number: EC 2.4.1.-
(26 Jun 1999)
alpha(1-6)mannosidase <enzyme> Human lysosomal enzyme highly specific for alpha 1-6 mannose residues; inhibited by swainsonine; not the same enzyme which is deficient in alpha-mannosidosis
Registry number: EC 3.2.1.-
(26 Jun 1999)
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