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experimental allergic encephalomyelitis <pathology> An autoimmune disease that can be induced in various experimental animals by the injection of homogenised brain or spinal cord in Freund's adjuvant. The antigen appears to be a basic protein present in myelin and the response is characterised by focal areas of lymphocyte and macrophage infiltration into the brain, associated with demyelination and destruction of the blood-brain barrier. Sometimes used as a model for demyelinating diseases, although whether this is entirely justifiable is not clear.
(18 Nov 1997)
extrinsic allergic alveolitis <radiology> Exposure to organic dust less than 5u in size, recurrent episodes of fever, chills, dry cough, dyspnea following exposure after 6 hr interval (10-40% assymptomatic), spontaneous resolution in 1-2 days, farmer's lung, Pandora's pneumonitis, bird-fancier's lung, mushroom worker's lung, bagassosis, malt worker's lung, maple bark disease, suberosis, sequoiosis see: acute extrinsic allergic alveolitis, hypersensitivity pneumonitis
(12 Dec 1998)
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