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active movement Movement effected by the organism itself, unaided by external influences.
(05 Mar 2000)
active mutant A mutant with overt phenotypic expression.
(05 Mar 2000)
active placebo <pharmacology> Any dummy medical treatment, originally, a medicinal preparation having no specific pharmacological activity against the patients illness or complaint given solely for the psychophysiological effects of the treatment, more recently, a dummy treatment administered to the control group in a controlled clinical trial in order that the specific and non-specific effects of the experimental treatment can be distinguished i.e., the experimental treatment must produce better results than the placebo in order to be considered effective.
(18 Nov 1997)
active principle A constituent of a drug, usually an alkaloid or glycoside, upon the presence of which the characteristic therapeutic action of the substance largely depends.
(05 Mar 2000)
active prophylaxis Use of an antigenic (immunogenic) agent to actively stimulate the immunological mechanism.
(05 Mar 2000)
active psychoanalysis Psychoanalysis in which the analyst intervenes directly and actively in the patient's life, e.g., by making prohibitions, assigning tasks.
(05 Mar 2000)
active pyruvate An intermediate formed in the oxidative decarboxylation of pyruvate.
Compare: pyruvate dehydrogenase (lipoamide).
Synonym: alpha-lactyl-thiamin pyrophosphate.
(05 Mar 2000)
active repressor A repressor that combines directly with an operator gene to repress the operator and its structural genes, thus repressing protein synthesis; active repressor may be repressed by an inducer, with resulting protein synthesis; a homeostatic mechanism for regulation of inducible enzyme systems.
(05 Mar 2000)
active site <chemistry> A specific region of an enzyme where a substrate binds and catalysis takes place (binding site).
(06 May 1997)
active splint A splint utilizing springs or elastic bands that aids in movements initiated by the patient by controlling the plane and range of motion.
Synonym: active splint, functional splint.
(05 Mar 2000)
active succinate The condensation product of succinic acid and CoA; one of the intermediates of the tricarboxylic acid cycle and a precursor in the synthesis of haem.
Synonym: active succinate, succinyl-CoA.
(05 Mar 2000)
active sulfate 3'-phosphoadenosine 5'-phosphosulfate;an intermediate in the formation of urinary ethereal sulfates, notable for containing a "high energy" sulfate bond; the 3'-OH of adenosine is replaced by -OPO3H2, the 5'-OH by -OP(O2H)-OSO3H.
Synonym: active sulfate.
Acronym: PAPS
(05 Mar 2000)
active transport <biochemistry, chemistry> Transport of ions, nutrients or other molecules into a cell against a concentration gradient, this requires the expenditure of energy through ATP hydrolysis.
(06 May 1997)
active treatment A therapeutic substance or course intended to ameliorate the basic disease problem, as opposed to supportive or palliative treatment.
Compare: causal treatment.
(05 Mar 2000)
active vasoconstriction Reduced caliber of a vessel caused by increased tonus in the smooth muscle in its walls.
(05 Mar 2000)
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