| PC | avoirdupois weight [Lat. pondus civile]; packed cells; paper chromatography; paracortex; parent cell... |
|---|---|
| SAICAR | sylaminoimidazole carboxylase |
| CoA | Coarctation of Aorta - Complications 1. Severe Hypertensi... |
| COA | Canadian Ophthalmological Association; Canadian Orthopaedic Association; certificate of authority; c... |
| CoA | coenzyme A |
| pyruvate carboxylase deficiency | An autosomal recessive pyruvate metabolism disorder resulting from absent or deficient expression of pyruvate carboxylase activity. Decreased production of oxaloacetate leads to decreased gluconeogenesis, thereby causing fasting hypoglycaemia, lactic acid acidosis, and decreased synthesis of amino acid neurotransmitters. Clinical presentations include acidosis, ataxia, mental retardation; sometimes co-occurs with leigh disease. (12 Dec 1998) |
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| pyruvic-malic carboxylase | <enzyme> An enzyme that catalyses the conversion of (s)-malate and NAD+ to oxaloacetate and NADH. Chemical name: (S)-Malate:NAD+ oxidoreductase Registry number: EC 1.1.1.37 (12 Dec 1998) |
| oxalosuccinic carboxylase | <enzyme> An enzyme of the oxidoreductase class that catalyses the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires magnesium, mn2+; it is activated by ADP, citrate, and calcium, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. (the NADP+ enzyme is EC 1.1.1.42.) Chemical name: Isocitrate:NAD+ oxidoreductase (decarboxylating) Registry number: EC 1.1.1.41 (12 Dec 1998) |
| acetyl | <biochemistry, chemistry> This is the radical of acetic acid, it contains a carbonyl and a methyl group that is single-bonded to the carbon, an oxygen is single-bonded to the carbon, and the carbon has two other bonds to the rest of the molecule. (09 Oct 1997) |
| acetyl-activating enzyme | A ligase that catalyses the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA. A key step in the activation of acetate. Synonym: acetate thiokinase, acetate-CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase. (05 Mar 2000) |
| acetyl chloride | CH3COCl;a colourless liquid used as a reagent; also corrosive, causing severe burns because of hydrolysis to HCl. (05 Mar 2000) |
| acetyl-coenzyme A | <enzyme> Condensation product of coenzyme A and acetic acid, symbolised as CoAS~COCH3; intermediate in transfer of two-carbon fragment, notably in its entrance into the tricarboxylic acid cycle and in fatty acid synthesis. This coenzyme plays a huge role in intermediary metabolism, in which cells synthesise, break down or use nutrient molecules for energy production, growth, etc. Acetyl-coenzyme A synthase is found in bacteria and plants and catalyses the reaction in which acetate enters metabolic pathways and forms acetyl-coenzyme A. Synonym: acetyl-coenzyme A, active acetate. (05 Mar 2000) |
| acetyl-coenzyme A-deacetylvindoline 4-O-acetyltransferase | <enzyme> Catalyses the final step in vindoline biosynthesis in catharanthus roseus Registry number: EC 2.3.1.107 Synonym: acadv-acetyltransferase, acetylcoenzyme a-deacetylvindoline-17-o-acetyltransferase (26 Jun 1999) |
| acetyl-coenzyme A-salutaridinol-7-O-acetyltransferase | <enzyme> Catalyses the transfer of acetyl from acetyl coenzyme a to the 7-oh group of salutaridinol which yields salutaridinol-7-o-acetate, an intermediate in morphine biosynthesis; from papaver somniferum plant cell cultures Registry number: EC 2.3.1.- Synonym: acetyl CoA-salutaridinol-7-o-acetyltransferase, salutaridinol-7-o-acetyltransferase (26 Jun 1999) |
| acetyl methylcarbinol | <chemical> 3-hydroxy-2-butanone. A product of fermentation. It is a component of the butanediol cycle in microorganisms. In mammals it is oxidised to carbon dioxide. Chemical name: 2-Butanone, 3-hydroxy- (12 Dec 1998) |
| acetyl phosphate | CH3CO-OPO32-;a "high energy" phosphate that acts as an acetate donor in the metabolism of various bacteria. Synonym: acetic phosphoric anhydride. (05 Mar 2000) |
| acetyl reduction assay | <investigation> A technique for measuring the nitrogen fixation activity in photosynthetic organisms. It uses a flame ionisation detector and a gas chromatography apparatus to determine the reduction of acetylene to ethylene by the enzyme nitrogenase. (06 May 1997) |
| acetyl sulfisoxazole | A derivative of sulfisoxazole with the same actions and uses; an antibacterial sulfa drug. (05 Mar 2000) |
| acetyl transacylase | Enzyme transferring acetyl from acetyl-CoA to acyl carrier protein and releasing CoA to begin fatty acid synthesis. Synonym: acetyl transacylase. (05 Mar 2000) |
| acetyl value | The milligrams of KOH required to neutralise the acetic acid produced by the hydrolysis of 1 g of acetylated fat; a measure of the hydroxy acids present in glycerides; notably high in castor oil. (05 Mar 2000) |