| iodotyrosine deiodinase defect | See: familial goiter. (05 Mar 2000) |
|---|---|
| oesophageal filling defect | <radiology> Tumour, carcinoma (oesophagus, stomach extending proximally), leiomyoma / leiomyosarcoma, polyp: fibrovascular, inflammatory, adenomatous, papilloma, carcinosarcoma, lymphoma, metastasis, oesophageal varix, extrinsic lesion (vascular impression, adenopathy, cyst), foreign body (12 Dec 1998) |
| osteoporotic marrow defect | Focal osteoporotic bone marrow defect of the jaw; a focal radiolucent defect composed of normal marrow. (05 Mar 2000) |
| Eisenmenger's defect | The combination of ventricular septal defect with pulmonary hypertension and consequent right-to-left shunt through the defect, with or without an associated overriding aorta. Synonym: Eisenmenger's defect, Eisenmenger's disease, Eisenmenger's tetralogy. (05 Mar 2000) |
| endocardial cushion defect | <radiology> Persistence of primitive atrioventricular canal and anomalies of AV valves associated with: Down syndrome: in 25% of Trisomy 21 an ECD is present; in 45% of ECD Trisomy 21 is present, asplenia/polysplenia types: complete (AV canal), partial findings: gooseneck deformity on angiogram, increased pulmonary vascularity, enlarged pulmonary artery, enlarged RV, LV, RA; normal LA (secondary to atrial septal defect) (12 Dec 1998) |
| enzyme defect | A disorder resulting from a deficiency (or functional abnormality) of an enzyme. In 1902 Archibald Garrod first attributed a disease to an enzyme defect: an inborn error of metabolism. Today, newborns are routinely screened for certain enzyme defects such as PKU (phenylketonuria) and galactosaemia, an error in the handling (metabolism) of the sugar galactose. (12 Dec 1998) |
| fibrous cortical defect | A common 1 to 3 cm defect in the cortex of a bone, most commonly the lower femoral shaft of a child, filled with fibrous tissue. Nonosteogenic or nonossifying fibroma by convention refers to lesions greater than 3 cm in diameter. See: nonossifying fibroma. Synonym: nonosteogenic fibroma. (05 Mar 2000) |
| uterine filling defect | <radiology> Technical, bubble, blood clot, mucoid material, congenital fold, pseudoadhesions / ridging -- folds long axis, neoplasm, submucosal leiomyoma, adenoma, endometrial carcinoma, pregnancy-related, pregnancy, molar pregnancy, retained conceptus, polyp, septated uterus, synechiae, IUD, iatrogenic (post-op) (12 Dec 1998) |
| filling defect | Displacement of contrast medium by a space-occupying lesion in a radiographic study of a contrast-filled hollow viscus, such as a polyp on a barium enema; also applied to defects in the otherwise uniform distribution of radionuclide in an organ, such as a metastasis in the liver on a 99mTc-sulfur colloid scan. (05 Mar 2000) |
| filling defect in renal collecting system | <radiology> Common causes: transitional cell carcinoma, blood clot, lucent calculus (urate) less common causes: fungus ball, sloughed papilla, fibroepithelial polyp, invasion by hypernephroma, malakoplakia, vessel impression, metastases (12 Dec 1998) |
| lambdoid suture defect | <radiology> Well-defined lucent lesion, classically unilateral, associated with neurofibromatosis (12 Dec 1998) |
| luteal phase defect | Inadequate function of the corpus luteum that may prevent a fertilized egg from implanting in the uterus or may lead to early pregnancy loss. (09 Oct 1997) |
| accessory thyroid | An isolated mass, or one of several such masses, of thyroid tissue, sometimes present in the side of the neck, or just above the hyoid bone (suprahyoid accessory thyroid gland), or even as low as the arch of the aorta. Synonym: glandula thyroidea accessoria, accessory thyroid, prehyoid gland, suprahyoid gland, thyroidea accessoria, thyroidea ima, Wolfler's gland. (05 Mar 2000) |
| accessory thyroid gland | An isolated mass, or one of several such masses, of thyroid tissue, sometimes present in the side of the neck, or just above the hyoid bone (suprahyoid accessory thyroid gland), or even as low as the arch of the aorta. Synonym: glandula thyroidea accessoria, accessory thyroid, prehyoid gland, suprahyoid gland, thyroidea accessoria, thyroidea ima, Wolfler's gland. (05 Mar 2000) |
| anaplastic carcinoma of the thyroid | <oncology, tumour> An aggressive form and rare form of thyroid cancer that is one of the most rapidly growing and invasive types of thyroid cancer. It commonly occurs in people over 60 years of age and may cause obstruction of the trachea. The cause is unknown but exposure to radiation may be a factor. Thyroid function tests are usually normal. Hoarse voice, cough and coughing up blood are common symptoms. Examination may reveal nodules in the thyroid gland. Diagnosis is made via biopsy. Treatment is surgical with or without radiation therapy. (27 Sep 1997) |