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topography <microscopy> The surface features of an object or how it looks its texture, direct relation between these features and materials properties (hardness, reflectivity etc.).
(05 Aug 1998)
topography, medical The systematic surveying, mapping, charting, and description of specific geographical sites, with reference to the physical features that were presumed to influence health and disease. Often associated with hippocrates, the process became a significant part of public health investigation and epidemiological methodology, particularly between the 17th and 19th centuries. Medical topography should be differentiated from epidemiology in that the former emphasizes geography whereas the latter emphasizes disease outbreaks. (dr. James h. Cassedy, nlm history of medicine division)
(12 Dec 1998)
topoinhibition Term used to describe the inhibition of cell proliferation as the cells become closely packed on a culture dish: generally superseded by the term density dependent inhibition.
(18 Nov 1997)
topoisomerase <enzyme> That change the degree of supercoiling in DNA by cutting one or both strands. Type I topoisomerases cut only one strand of DNA, type I topoisomerase of E. Coli (omega protein) relaxes negatively supercoiled DNA and does not act on positively supercoiled DNA. Type II topoisomerases cut both strands of DNA, type II topoisomerase of E. Coli (DNA gyrase) increases the degree of negative supercoiling in DNA and requires ATP. It is inhibited by several antibiotics, including nalidixic acid and ovobiocin.
(18 Nov 1997)
topoisomers Different forms of a closed, circular DNA molecule, in each, only thelinking number differs.
(09 Oct 1997)
Topolanski Alfred, Austrian ophthalmologist, 1861-1960.
See: Topolanski's sign.
(05 Mar 2000)
Topolanski's sign <clinical sign> Congestion of the pericorneal region of the eye in Graves' disease.
(05 Mar 2000)
topology <study> The art of, or method for, assisting the memory by associating the thing or subject to be remembered with some place.
Origin: Gr. Place.
Source: Websters Dictionary
(01 Mar 1998)
toponarcosis A localised cutaneous anaesthesia.
Origin: topo-+ narcosis
(05 Mar 2000)
toponym A regional term; one designating a region as distinguished from the name of a structure, system, or organ.
Origin: topo-+ G. Onyma, name
(05 Mar 2000)
toponymy Topical or regional nomenclature, as distinguished from organonymy.
Origin: topo-+ G. Onyma, name
(05 Mar 2000)
topopathogenesis Topography of lesions related to their pathogenesis.
Origin: topo-+ pathogenesis
(05 Mar 2000)
topophobia <psychology> A neurotic dread of or related to a particular place or locality.
Origin: topo-+ G. Phobos, fear
(05 Mar 2000)
topophylaxis Prevention of arsphenamine shock by a tourniquet applied to the limb above the site of injection and its slow release five or six minutes later.
Origin: topo-+ G. Phylaxis, protection
(05 Mar 2000)
toposcope <instrument> An apparatus to project the electrical activity of the cerebral cortex as a spatial coordinate visual system.
Origin: topo-+ G. Skopeo, to view
(05 Mar 2000)
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topographic anatomy the study of parts in their relation to surrounding parts.
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
top- Roscoe Dillon was a small-time crook who turned his childhood obsession with tops into a criminal persona. Roscoe taught himself how to spin around fast enough to deflect bullets and produce other semi-useful effects. The top soon discovered that the spinning somehow increased his intelligence as well, allowing him to create a variety of trick tops. His unique gimmick and moderate success in crime soon made him a respected member of the Flash's rogues gallery. ...
Ãâó: en.wikipedia.org/wiki/Top_(comics)
topoisomerase Topoisomerases (type I: EC 5.99.1.2, type II: EC 5.99.1.3) are enzymes that act on the topology of DNA. The double-helical configuration that DNA strands naturally reside in makes them difficult to separate, and yet they must be separated by helicase proteins if other enzymes are to transcribe the sequences that encode proteins, or if chromosomes are to be replicated. ...
Ãâó: en.wikipedia.org/wiki/Topoisomerase
topophobia The English suffix -phobia is technically used to describe irrational, disabling fear as a mental disorder, and commonly misused to describe hatred of a particular thing or subject. Everyday language has misused the use of this suffix as a mild or irrational fear with no serious substance; however, its origin is from areas of psychiatry which study serious phobias which disable a person's life. ...
Ãâó: en.wikipedia.org/wiki/Topophobia
toponym A place name.
Ãâó: www.geocities.com/TimesSquare/Labyrinth/2398/bginf...
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TOP a hypothetical quark with a charge of +2/3 and a mass more than 100,000 times that of an electron
TOP roast cut from the round
TOP the highest or uppermost side of anything
TOP computer
TOP (British) excellent
TOP surpassing in quality
TOP unstable by being overloaded at the top
TOP (British) excellent
TOP of the highest rank
TOP surpassing in quality
TOP of the highest rank
TOP the highest official level of classification of documents
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