| sign language | A system of hand gestures used for communication by the deaf or by people speaking different languages. (12 Dec 1998) |
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| sign of elongation | <microscopy> Referring to the elongation of a substance in relation to refractive indices. If it is elongated in the direction of the high refractive index, it is said to have a positive sign of elongation. If it is elongated in the direction of the low refractive index, it has a negative sign of elongation, not to be confused with the sign of double refraction (i.e., optic sign). (05 Aug 1998) |
| sign of the orbicularis | In hemiplegia, inability to voluntarily close the eye on the paralysed side except in conjunction with closure of the other eye. Synonym: Revilliod's sign. (05 Mar 2000) |
| signal | 1. Noticeable; distinguished from what is ordinary; eminent; remarkable; memorable; as, a signal exploit; a signal service; a signal act of benevolence. "As signal now in low, dejected state As erst in highest, behold him where he lies." (Milton) 2. Of or pertaining to signals, or the use of signals in conveying information; as, a signal flag or officer. The signal service, a bureau of the government (in the United States connected with the War Department) organised to collect from the whole country simultaneous raports of local meteorological conditions, upon comparison of which at the central office, predictions concerning the weather are telegraphed to various sections, where they are made known by signals publicly displayed. Signal station, the place where a signal is displayed; specifically, an observation office of the signal service. Synonym: Eminent, remarkable, memorable, extraordinary, notable, conspicuous. Origin: From signal, n., cf. F. Signale. Source: Websters Dictionary (01 Mar 1998) |
| signal detection (psychology) | A theory of psychophysics which characterises not only the acuity of an individual's discrimination but also the psychological factors that bias his judgment. (12 Dec 1998) |
| signal node | A firm supraclavicular lymph node, especially on the left side, sufficiently enlarged that it is palpable from the cutaneous surface; such a lymph node is so termed because it may be the first recognised presumptive evidence of a malignant neoplasm in one of the viscera. A signal node that is known to contain a metastasis from a malignant neoplasm is sometimes designated by an old eponym, Troisier's ganglion. Synonym: jugular gland, Virchow's node. (05 Mar 2000) |
| signal peptidase | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal peptidase complex | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal peptide | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal peptide p25-subunit IV cytochrome oxidase | <chemical> Similar in action to melittin Synonym: p25 presequence peptide-cytochrome oxidase, pre-ctox p25 (26 Jun 1999) |
| signal peptides | Additional polypeptide sequence of 25 to 30 residues at the amino-terminal or carboxy-terminal end of proteins. The signal sequence signals the cellular fate or destination of a newly synthesised protein directing it to its ultimate destination in the cell. These leaders are recognised by the signal recognition particle and bound by specific receptor sites on the outer surface of the endoplasmic reticulum. They are then transported into the cisterna of the endoplasmic reticulum and from there directed to their ultimate destination in the cell. In prokaryotes, the signal peptides attach to the plasma membrane. These signal sequences are ultimately removed by specific peptidases. (12 Dec 1998) |
| signal processing, computer-assisted | Computer-assisted processing of electric, ultrasonic, or electronic signals to interpret function and activity. (12 Dec 1998) |
| signal recognition particle | A complex between a 7S RNA and six proteins. SRP binds to the nascent polypeptide chain of eukaryotic proteins with a signal sequence and halts further translation until the ribosome becomes associated with the rough endoplasmic reticulum. One of the SRP proteins (srp54) binds GTP and in association with 7SRNA and srp19 has GTPase activity. (18 Nov 1997) |
| signal recognition particle receptor | Receptor for the signal recognition particle (SRP) found in the membrane of the endoplasmic reticulum. Also called docking protein. Heterodimeric, both protomers having GTP binding capacity, though dissimilar binding sites. Not until the complex of SRP, ribosome, message and nascent polypeptide chain binds to the SRP receptor is the block to further chain elongation released and concurrently the SRP is released, leaving the ribosome attached to the endoplasmic reticulum membrane. Cotranslational transport of the polypeptide delivers it into the lumen of the ER. (18 Nov 1997) |
| signal response coupling | The cascade of processes by which an extracellular signal (typically a hormone or neurotransmitter) interacts with a receptor at the cell surface, causing a change in the level of a second messenger for example calcium or cyclic AMP) and ultimately effects a change in the cells functioning (for example: triggering glucose uptake or initiating cell division). Can also be applied to sensory signal transduction, for example of light at photoreceptors. (18 Nov 1997) |
| sign language |
language expressed by visible hand gestures
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| signal |
any communication that encodes a message; "signals from the boat suddenly stopped" sign: communicate silently and non-verbally by signals or signs; "He signed his disapproval with a dismissive hand gesture"; "The diner signaled the waiters to bring the menu" any incitement to action; "he awaited the signal to start"; "the victory was a signal for wild celebration" notably out of the ordinary; "the year saw one signal triumph for the Labour party" bespeak: be a signal for or a symptom of; "These symptoms indicate a serious illness"; "Her behavior points to a severe neurosis"; "The economic indicators signal that the euro is undervalued" an electric quantity (voltage or current or field strength) whose modulation represents coded information about the source from which it comes
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| signature |
your name written in your own handwriting touch: a distinguishing style; "this room needs a woman's touch" a melody used to identify a performer or a dance band or radio/tv program key signature: the sharps or flats that follow the clef and indicate the key a sheet with several pages printed on it; it folds to page size and is bound with other signatures to form a book
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| significant |
important in effect or meaning; "a significant change in tax laws"; "a significant change in the Constitution"; "a significant contribution"; "significant details"; "statistically significant" fairly large; "won by a substantial margin" too closely correlated to be attributed to chance and therefore indicating a systematic relation; "the interaction effect is significant at the .01 level"; "no significant difference was found" meaning(a): rich in significance or implication; "a meaning look"; "pregnant with meaning"
출처: wordnet.princeton.edu/perl/webwn
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| significant other |
domestic partner: a person (not necessarily a spouse) with whom you cohabit and share a long-term sexual relationship
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| SIG | an S-shaped dural sinus on the temporal and occipital bones |
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| SIG | tributaries of the inferior mesenteric vein |
| SIG | of or relating to the sigmoid flexure in the large intestine |
| SIG | surgical removal of part or all of the sigmoid colon (usually to remove a malignant tumor) |
| SIG | an endoscope (a flexible fiberoptic probe) for examining the sigmoid colon |
| SIG | visual examination (with a sigmoidoscope) of the lower third of the colon in a search for polyps |
| SIG | Austrian neurologist who originated psychoanalysis (1856-1939) |
| SIG | United States composer (born in Hungary) who composed operettas (1887-1951) |
| SIG | structure displaying a board on which advertisements can be posted |
| SIG | a perceptible indication of something not immediately apparent (as a visible clue that something has happened) |
| SIG | any communication that encodes a message |
| SIG | a public display of a (usually written) message |