| NCMC | natural cell-mediated cytotoxicity |
|---|---|
| NK | Commission on [Anatomical] Nomenclature [Ger. Nomenklatur Kommission]; natural killer [cell]; neurok... |
| NKCA | natural killer cell activity |
| NKSF | natural killer cell stimulatory factor |
| CHARGE | coloboma, heart disease, atresia choanae, retarded growth and retarded development and/or CNS anomal... |
natural purification (자정 작용
| feedback regulation | <physiology> Control mechanism that uses the consequences of a process to regulate the rate at which the process occurs: if, for example: the products of a reaction inhibit the reaction from proceeding (or slow down the rate of the reaction), then there is negative feedback, something that is very common in metabolic pathways. Positive feedback is liable to lead to exponential increase and may be explosively dangerous in some cases. Other examples are the action of voltage dependent sodium channels in generating action potentials and the activation of blood clotting factors V and VIII by thrombin. Without damping, feedback can lead to resonance (hunting) and oscillation in the system. (18 Nov 1997) |
|---|---|
| up-regulation | Opposite of down-regulation. (05 Mar 2000) |
| up-regulation (physiology) | Process that increases ligand/receptor interactions due to an increase in the number of available receptors. (12 Dec 1998) |
| B-cell differentiation/growth factors | Various substances, usually obtained from the supernatant of T-cell cultures, such as interleukin 4, 5, and 6. These substances are necessary for B-cell growth, maturation, and differentiation into plasma cells or B memory cells. (05 Mar 2000) |
| cell growth | <cell biology> Usually used to mean increase in the size of a population of cells though strictly should be reserved for an increase in cytoplasmic volume of an individual cell. (26 Mar 1998) |
| haematopoietic cell growth factors | These growth factors comprise a family of haematopoietic regulators with biological specificities defined by their ability to support proliferation and differentiation of blood cells of different lineages. Erythropoietin and the colony-stimulating factors belong to this family. Some of these factors have been studied and used in the treatment of chemotherapy-induced neutropenia, myelodysplastic syndromes, and bone marrow failure syndromes. (12 Dec 1998) |
| stem cell growth factors | <growth factor> Compounds, usually proteins, that make stem cells grow faster. (26 Mar 1998) |
| T-cell growth factor | <cytokine> A hormone-like substance released by stimulated T lymphocytes, causes activation and differentiation of other T lymphocytes independently of antigen. A type of interleukin, a chemical messenger, a substance that can improve the body's response to disease. It stimulates the growth of certain disease-fighting blood cells in the immune system. It is secreted by Thl CD4 cells to stimulate CD8 cytotoxic T-1yrnphocytes. Interleukin 2 also increases the proliferation and maturation of the CD4 cells themselves. During HIV infection, Interleukin-2 production gradually declines. Use of interleukin 2 therapy is under study as a way to raise CD4 cell counts and restore immune function. Acronym: IL-2 (12 Dec 1998) |
| T-cell growth factor-1 | <cytokine> A hormone-like substance released by stimulated T lymphocytes, causes activation and differentiation of other T lymphocytes independently of antigen. A type of interleukin, a chemical messenger, a substance that can improve the body's response to disease. It stimulates the growth of certain disease-fighting blood cells in the immune system. It is secreted by Thl CD4 cells to stimulate CD8 cytotoxic T-1yrnphocytes. Interleukin 2 also increases the proliferation and maturation of the CD4 cells themselves. During HIV infection, Interleukin-2 production gradually declines. Use of interleukin 2 therapy is under study as a way to raise CD4 cell counts and restore immune function. Acronym: IL-2 (12 Dec 1998) |
| T-cell growth factor-2 | <cytokine> A soluble cytokine factor produced by activated T-lymphocytes that promotes antibody production by causing proliferation and differentiation of B-cells. Interleukin-4 induces the expression of class II major histocompatibility complex and fc receptors on B-cells. It also acts on T-lymphocytes, mast cell lines, and several other haematopoietic lineage cells including granulocyte, megakaryocyte, and erythroid precursors, as well as macrophages. Acronym: IL-4 (12 Dec 1998) |
| acquired immunity | <immunology> A form of cellular defense which identifies certain foreign substances (antigens) as harmful to the body. For this reason, the body can acquire resistance to a particular foreign agent. These foreign agents are then attacked by sensitised T lymphocytes (cellular immunity). White blood cells, plasma cells, B lymphocytes and other specialised immune system cells act in concert with T lymphocytes to produce antibodies (humoral immunity) that attach to the antigen directing T-cells to attack. Antibodies also stimulate the release of special chemical mediators in the blood (for example complement, interferon) that further enhance antigen destruction. (13 Nov 1997) |
| active immunity | <immunology> An organisms resistance to disease or infection, developed because the organisms immune system has produced antibodies after an infection or innoculation. (06 May 1997) |
| adoptive immunity | <immunology> Immunity to disease or infection conferred on a previously non-immune individual by transferring lymphocytes from a previously immune individual to the non-immune individual. (15 Jan 1998) |
| allograft immunity | <immunology> The recipient's immune system rejects tissue grafted from a genetically dissimilar donor (of the same species) and stages an immune attack against it. (09 Oct 1997) |
| antiviral immunity | Immunity resulting from virus infection, either naturally acquired or produced by intentional vaccination; compared to some bacterial immunity's, it is of relatively long duration, but this may be the result of infection-immunity rather than being peculiar to virus infection per se, since it occurs also in bacterial immunity after infections such as typhoid fever. (05 Mar 2000) |