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NADP <chemical> Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (nmn) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidised (NADP+) and reduced (NADPH).
Chemical name: Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'-5'-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium, inner salt
(12 Dec 1998)
NADP phosphatase <enzyme> Forms nad+ by hydrolysis of 3'-phosphate
Registry number: EC 3.1.3.-
Synonym: nadp+ phosphatase
(26 Jun 1999)
NADP transhydrogenase <enzyme> An enzyme present in the mitochondrial membrane of animals and in microorganisms. In the presence of energy (ATP) it catalyses reversibly the reduction of NAD by NADPH to yield NADP and NADH. This reaction permits the utilization of the reducing properties of NADPH by the respiratory chain and in the reverse direction it allows the reduction of NADP for biosynthetic purposes.
Chemical name: NADPH:NAD+ oxidoreductase (B-specific)
Registry number: EC 1.6.1.1
(12 Dec 1998)
NADP+ <abbreviation> Nicotinamide adenine dinucleotide phosphate (oxidised form).
(05 Mar 2000)
NADP+-dependent serine dehydrogenase <enzyme> Catalyses the oxidation of the hydroxyl group of ser to form 2-aminomalonate saemialdehyde; from agrobacterium tumefaciens.
Registry number: EC 1.1.1.-
Synonym: nadp+ ser dehydrogenase
(26 Jun 1999)
NADP-dependent flavonol reductase <enzyme> Isolated from maise
Registry number: EC 1.1.1.-
Synonym: a1 gene product
(26 Jun 1999)
NADP-reducing hydrogenase <enzyme> Operon from desulfovibrio contains 4 genes: hnda, hndb, hndc and hndd; does not reduce nad; genbank u07229
Registry number: EC 1.12.1.-
Synonym: hnd gene product, hndabcd gene product
(26 Jun 1999)
NADPH <abbreviation> Nicotinamide adenine dinucleotide phosphate (reduced form).
(05 Mar 2000)
NADPH - phenanthrenequinone oxidoreductase <enzyme> Cytosolic enzyme from channel catfish; involved in futile redox cycling forming h2o2 leading to oxidative stress
Registry number: EC 1.6.99.-
Synonym: NADPH pq oxidoreductase
(26 Jun 1999)
NADPH dehydrogenase <enzyme> A flavoprotein that reversibly oxidises NADPH to NADP and a reduced acceptor.
Chemical name: NADPH:(acceptor) oxidoreductase
Registry number: EC 1.6.99.1
(12 Dec 1998)
NADPH dehydrogenase (quinone) A flavoprotein similar to NADH dehydrogenase (quinone), but oxidizing NADPH.
Synonym: DT-diaphorase, menadione reductase, phylloquinone reductase, quinone reductase.
(05 Mar 2000)
NADPH diaphorase <enzyme> A flavoprotein that reversibly oxidises NADPH to NADP and a reduced acceptor.
Chemical name: NADPH:(acceptor) oxidoreductase
Registry number: EC 1.6.99.1
(12 Dec 1998)
NADPH oxidase <enzyme> A plasma membrane-associated enzyme complex that catalyses the univalent reduction of oxygen using NADPH as an electron donor. The superoxide anion formed acts as an oxidant in the phagocyte microbicidal system, proceeding through a series of electron transfer reactions that form the respiratory burst. Various genetic defects in the system result in chronic granulomatous disease (granulomatous disease, chronic).
Registry number: EC 1.6.-
(12 Dec 1998)
NADPH-cytochrome c2 reductase <enzyme> An enzyme catalyzing the reduction of 2 ferricytochrome c2 to 2 ferrocytochrome c2 at the expense of NADPH.
Synonym: cytochrome c2 reductase.
(05 Mar 2000)
NADPH-ferrihemoprotein reductase <enzyme> A flavoprotein that catalyses the reduction of haem-thiolate-dependent monooxygenases and is part of the microsomal hydroxylating system. Its physiological acceptor is probably cytochrome p-450.
Chemical name: NADPH:ferrihemoprotein oxidoreductase
Registry number: EC 1.6.2.4
(12 Dec 1998)
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