| mitotic rate | The proportion of cells in a tissue that are undergoing mitosis, expressed as a mitotic index or, roughly, as the number of cells in mitosis in each microscopic high-power field in tissue sections. (05 Mar 2000) |
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| mitotic recombination | <genetics, molecular biology> Somatic crossing over. Crossing over can occur between homologous chromosomes during mitosis, but is very rare because the chromosomes do not normally pair. When it occurs it can lead to new combinations of previously linked genes. Although infrequent, mitotic recombination has been utilised for genetic analysis in Aspergillus and in studies on developmental compartments in Drosophila where the frequency of mitotic recombination can be increased by X irradiation. (18 Nov 1997) |
| mitotic segregation | <genetics> Mitotic recombination. (18 Nov 1997) |
| mitotic shake off method | <cell biology, procedure> A method of collecting cells in mitosis, so that the chromosomes can be examined and the karyotype determined. Many cultured cells round up during mitosis and so become less firmly attached to the culture substratum. Cells in mitosis thus can be removed into suspension by gentle shaking of the culture vessel, leaving the nonmitotic cells still attached. The number of cells that are in mitosis is usually increased by using a drug, such as colcemid that blocks mitosis at metaphase. (18 Nov 1997) |
| mitotic spindle | See: spindle and mitosis. (18 Nov 1997) |
| mitotic spindle apparatus | An organelle consisting of three components: 1) the astral microtubules, which form around each centrosome and extend to the periphery; 2) the polar microtubules which extend from one spindle pole to the equator; and 3) the kinetochore microtubules, which connect the centromeres of the various chromosomes to either centrosome. (12 Dec 1998) |
| mitoxantrone | <chemical> An anthracenedione antineoplastic agent. It is particularly effective against advanced breast cancer, acute leukaemia, and malignant lymphoma. It has mild side effects, especially with respect to nausea, vomiting, hair loss, and cardiotoxicity. Pharmacological action: analgesics, antineoplastic agent. Chemical name: 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)- (12 Dec 1998) |
| mitoxantrone hydrochloride | 1,4-Dihydro-5,8-bis[[2-[2-hydroxyethyl)-amino]ethyl]anthraquinone dihydrochloride;a synthetic anti-neoplastic used intravenously in the initial therapy for acute nonlymphocytic leukaemia in adults. (05 Mar 2000) |
Synonyms : ERK2 Brain Kinase PK40, MAPK1 Mitogen-Activated Protein Kinase, MAPK2 Mitogen-Activated Protein Kinase, p40 Mitogen-Activated Protein Kinase, p41 Mitogen-Activated Protein Kinase, p42(Mapk), p42(Mapk) Kinase, Extracellular Signal Regulated Kinase 2
Synonyms : JNK3 Mitogen Activated Protein Kinase, MAP Kinase p49(3F12), MAPK10 Mitogen-Activated Protein Kinase, Mitogen Activated Protein Kinase p49(3F12), Stress-Activated Protein Kinase JNK3, c-jun Kinase 3, c-jun N-Terminal Kinase 3, p49 3F12 Kinase, p54-SAPK(beta)
Synonyms : MAPK11 Mitogen-Activated Protein Kinase, Mitogen-Activated Protein Kinase Eleven, SAP Kinase-2, SAPK2, SAPK2b, Stress-Activated Protein Kinase 2, Stress-Activated Protein Kinase 2b, p38(beta) MAP Kinase, p38beta MAP Kinase, Kinase, p38beta MAP, SAP Kinase 2
Synonyms : ERK6 Protein, Extracellular Signal-Regulated Kinase 6, MAPK12 Mitogen-Activated Protein Kinase, SAP Kinase 3, SAP Kinase-3, SAPK3, Stress-Activated Protein Kinase-3, p38gamma MAP Kinase, Extracellular Signal Regulated Kinase 6, Kinase 3, SAP, Kinase-3, SAP
Synonyms : MAPK13 Mitogen-Activated Protein Kinase, SAPK4, Stress-Activated Protein Kinase 4, p38delta, p38delta MAP Kinase, Kinase, p38delta MAP, MAP Kinase, p38delta, MAPK13 Mitogen Activated Protein Kinase, Mitogen Activated Protein Kinase 13
| mitochondria |
Parts of a cell where aerobic production (also called cell respiration) takes place.
출처: www.stjude.org/glossary
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| mitomycin |
An anticancer drug that belongs to the family of drugs called antitumor antibiotics.
출처: www.stjude.org/glossary
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| mitosis |
The process of division of somatic cells in which each daughter cell receives the same amount of DNA as the parent cell.
출처: www.stjude.org/glossary
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| mitotane |
An anticancer drug used in treating adrenocortical cancer and ACTH-producing pituitary tumors (Cushing's disease).
출처: www.stjude.org/glossary
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| mitolactol |
An anticancer drug that belongs to the family of drugs called alkylating agents.
출처: www.stjude.org/glossary
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