| initiation factors | The set of catalytic proteins required, in addition to mRNA and ribosomes, for protein synthesis to begin. In bacteria three distinct proteins have been identified: if 1 (8 kD), IF 2 (75 kD) and IF 3 (30 kD). at least 6-8 proteins have been identified in eukaryotes. IFs 1 and 2 enhance the binding of initiator tRNA to the initiation complex. (18 Nov 1997) |
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| ischemia-modifying factors | Various factors that play a role in determining the extent of necrosis with cerebral stroke; these include blood viscosity and osmolality, the blood pressure, and the anatomy of the neck and intracranial arteries. (05 Mar 2000) |
| oesophageal carcinoma risk factors | <radiology> P Plummer-Vinson Web, A achalasia, alcohol, B Barrett oesophagus, S stricture, T tylosis, tobacco see: oesophageal carcinoma (12 Dec 1998) |
| thyroid carcinoma risk factors | <radiology> Increased risk of malignancy: young female, male, history of radiation to head or neck, hard lesion, other neck masses, no shrinkage on TSH, family hx of thyroid carcinoma see: thyroid carcinoma (12 Dec 1998) |
| time factors | Elements of limited time intervals, contributing to particular results or situations. (12 Dec 1998) |
| transcription factors | Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process. (12 Dec 1998) |
| transcription factors, tfii | The so-called general transcription factors that bind to RNA polymerase II and that are required to initiate transcription. They include tfiia, tfiib, tfiid, tfiie, tfiif, tfiih, tfii-I, and tfiij. In vivo they apparently bind in an ordered multi-step process and/or may form a large preinitiation complex called RNA polymerase II holoenzyme. (12 Dec 1998) |
| transcription factors, tfiii | Factors that bind to RNA polymerase III and aid in transcription. They include the assembly factors tfiiia and tfiiic and the initiation factor tfiiib. All combine to form a preinitiation complex at the promotor that directs the binding of RNA polymerase III. (12 Dec 1998) |
| epidemiologic factors | Events, characteristics, or other definable entities that have the potential to bring about a change in a health condition or other defined outcome. (12 Dec 1998) |
| essential food factors | Those substances required in the diet: certain amino acids and unsaturated fatty acids, vitamins, essential minerals, etc. (05 Mar 2000) |
| Factors I XII | <haematology> Blood clotting factors, especially from humans. These factors form a cascade in which the activation of the first factor leads to enzymic attack on the next factor and so on, finally resulting in blood clotting. (18 Nov 1997) |
| uncoupling factors | Substances such as dinitrophenol that allow oxidation in mitochondria to proceed without the usual concomitant phosphorylation to produce ATP; these poisons thus "uncouple" oxidation and phosphorylation. Synonym: uncoupling factors. (05 Mar 2000) |
| lactose factors | Plasmids which determine the ability of a bacterium to ferment lactose. (12 Dec 1998) |
| LE factors | Antinuclear immunoglobulins in plasma of persons with disseminated lupus erythematosus, associated with positive LE tests. (05 Mar 2000) |
| leukocyte migration-inhibitory factors | Protein factor(s) released by sensitised lymphocytes (and possibly other cells) that inhibit the movement of leukocytes, especially polymorphonuclear cells, away from their site of release. Assays for these factors are used as tests for cellular immunity. Two of the common assays are the leukocyte migration capillary tube technique (lmct) and the leukocyte migration agarose technique (lmat). (12 Dec 1998) |