| AJCC | American Joint Commission for Cancer |
|---|---|
| AJCCS | American Joint Committee on Cancer Staging |
| BC | Bachelor of Surgery [Lat. Baccal-aureus Chirurgiae]; back care; bactericidal concentration; basal ce... |
| BCA | balloon catheter angioplasty; bicinchoninic acid; blood color analyzer; Blue Cross Association; bran... |
| BCDDP | Breast Cancer Detection Demonstration Project |
| sex chromosomes | The homologous chromosomes that are dissimilar in the heterogametic sex. There are the x chromosome, the y chromosome, and the w, z chromosomes (in animals in which the female is the heterogametic sex (the silkworm moth bombyx mori, for example). In such cases the w chromosome is the female-determining and the male is zz. (12 Dec 1998) |
|---|---|
| nonhomologous chromosomes | <genetics> Chromosome's that are not members of the same pair. (05 Mar 2000) |
| double minute chromosomes | <genetics, molecular biology> Paired, extrachromosomal elements lacking centromeres, often associated with a drug resistance gene. (05 Mar 2000) |
| duplication of chromosomes | A chromosome aberration resulting from unequal crossing over or exchange of segments between two homologous chromosomes; one chromosome of the pair loses a small segment, while the other gains this segment; the chromosome gaining the segment has undergone duplication while its homologue has undergone deletion. See: haemoglobin Lepore. (05 Mar 2000) |
| inversion of chromosomes | A chromosome aberration resulting from a double break in a segment of the chromosome, with end for end rotation of the fragment between the fracture lines, and refusion of the fragments; this results in reversal of the order of genes in that segment. (05 Mar 2000) |
| yeast artificial chromosomes | Yeast DNA sequences that have incorporated into them very large foreign DNA fragments; the recombinant DNA is then introduced into the yeast by transformation; the use of yeast artificial chromosomes permits the cloning of large genes with their flanking regulatory sequences. (05 Mar 2000) |
| genes | Located in the nucleus of the cell, genes contain hereditary information that is transferred from cell to cell. (09 Oct 1997) |
| genes, abl | Retrovirus-associated DNA sequences (abl) originally isolated from the abelson murine leukaemia virus (ab-mulv). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukaemia. (12 Dec 1998) |
| genes, apc | Tumour suppressor genes located in the 5q21 region on the long arm of chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (apc stands for adenomatous polyposis coli) and gardner's syndrome, as well as some sporadic colourectal cancers. (12 Dec 1998) |
| genes, arac | Regulatory genes which encode a cyclic AMP receptor protein required for l-arabinose utilization in e. Coli. It is an example of positive control or regulation of gene expression in the bacterial operon. (12 Dec 1998) |
| genes, archaeal | The genetic material of archaea. (12 Dec 1998) |
| genes, bacterial | The genetic material of bacteria. (12 Dec 1998) |
| genes, bcl-1 | The B-cell leukaemia/lymphoma-1 genes, associated with various neoplasms when overexpressed. Overexpression results from the t(11;14) translocation, which is characteristic of mantle zone-derived B-cell lymphomas. The human c-bcl-1 gene is located at 11q13 on the long arm of chromosome 18. (12 Dec 1998) |
| genes, bcl-2 | The B-cell leukaemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18. (12 Dec 1998) |
| genes, BRCA1 | Tumour suppressor genes located on human chromosome 17q12-21. The mutation of these genes is associated with the formation of familial breast and ovarian cancer. (12 Dec 1998) |