| Graefenberg ring | An obsolete term for a silver or silkworm gut ring designed for insertion into the uterine cavity as a means of contraception. (05 Mar 2000) |
|---|---|
| Graefenberg, Ernst | <person> German gynecologist in America, 1881-1957. See: Graefenberg ring. (05 Mar 2000) |
| graf | A German title of nobility, equivalent to earl in English, or count in French. See Earl. Origin: G. Cf. -grave. Source: Websters Dictionary (01 Mar 1998) |
| Graffi's virus | A mouse myeloleukaemia virus from filtrates of transplantable tumours; possibly related to Gross' virus. (05 Mar 2000) |
| Graffi, Arnold | <person> German pathologist, *1910. See: Graffi's virus. (05 Mar 2000) |
| graft | To insert scions from one tree, or kind of tree, etc, into another; to practice grafting. A small shoot or scion of a tree inserted in another tree, the stock of which is to support and nourish it. The two unite and become one tree, but the graft determines the kind of fruit. A branch or portion of a tree growing from such a shoot. <surgery> A portion of living tissue used in the operation of autoplasty. Origin: OE. Graff, F. Greffe, originally the same word as OF. Grafe pencil, L. Graphium, Gr, fr. To write; prob. Akin to E. Carve. So named from the resemblance of a scion or shoot to a pointed pencil. Cf. Graphic, Grammar. 1. To insert (a graft) in a branch or stem of another tree; to propagate by insertion in another stock; also, to insert a graft upon. [Formerly written graff. 2. <surgery> To implant a portion of (living flesh or akin) in a lesion so as to form an organic union. 3. To join (one thing) to another as if by grafting, so as to bring about a close union. "And graft my love immortal on thy fame !" (Pope) 4. To cover, as a ring bolt, block strap, splicing, etc, with a weaving of small cord or rope-yarns. Origin: F. Greffer. See Graft. Source: Websters Dictionary (01 Mar 1998) |
| graft enhancement, immunologic | The induction of prolonged survival and growth of allografts of either tumours or normal tissues which would ordinarily be rejected. It may be induced passively by introducing graft-specific antibodies from previously immunised donors, which bind to the graft's surface antigens, masking them from recognition by T-cells; or actively by prior immunization of the recipient with graft antigens which evoke specific antibodies and form antigen-antibody complexes which bind to the antigen receptor sites of the T-cells and block their cytotoxic activity. (12 Dec 1998) |
| graft occlusion | <physiology> Obstruction of flow in biological or prosthetic vascular grafts. (12 Dec 1998) |
| graft rejection | <haematology, immunology> When donated bone marrow infused during a bone marrow transplant is rejected by the patients body or does not take. (16 Dec 1997) |
| graft survival | <haematology> The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host. (12 Dec 1998) |
| graft-versus-host disease | <haematology> A common and serious, complication of bone marrow transplantation where there is a reaction of donated bone marrow against a patient's own tissue. When donor lymphocytes or a graft containing lymphocytes that are immunologically competent are given to a patient that has low immunological competence, an incompatibility reaction can result. This is due to antibodies from the donor against antigens in the host. This is due to mismatch of MHC Class I antigens and can produce lymphocyte clones that will react by a variety of processes against the host and cause damage. The clinical condition can be fatal and is due to the donor's immune cells recognising the host cells as foreign. The clinical entity characterised by anorexia, diarrhoea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the graft-versus-host reaction. It can occur in either chronic or acute forms and is treatable by immunosuppressive drugs. Seen most commonly following bone marrow transplantation, acute disease is seen after 5-40 days and chronic disease weeks to months after transplantation, affecting, principally, the gastrointestinal tract, liver, and skin. Radiological appearances of the gastrointestinal tract include; thickened wall, mucosal folds thickened or effaced, increased secretions most likely to be rapid transit of GI tract, mass most likely to be focal oedema, fibrosis, hallmark: diffuse, uniform thickening of small bowel. Synonym: GVH disease. Acronym: GVHD (20 Sep 2002) |
| graft-versus-host reaction | <haematology> A common and serious, complication of bone marrow transplantation where there is a reaction of donated bone marrow against a patient's own tissue. When donor lymphocytes or a graft containing lymphocytes that are immunologically competent are given to a patient that has low immunological competence, an incompatibility reaction can result. This is due to antibodies from the donor against antigens in the host. This is due to mismatch of MHC Class I antigens and can produce lymphocyte clones that will react by a variety of processes against the host and cause damage. The clinical condition can be fatal and is due to the donor's immune cells recognising the host cells as foreign. The clinical entity characterised by anorexia, diarrhoea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the graft-versus-host reaction. It can occur in either chronic or acute forms and is treatable by immunosuppressive drugs. Seen most commonly following bone marrow transplantation, acute disease is seen after 5-40 days and chronic disease weeks to months after transplantation, affecting, principally, the gastrointestinal tract, liver, and skin. Radiological appearances of the gastrointestinal tract include; thickened wall, mucosal folds thickened or effaced, increased secretions most likely to be rapid transit of GI tract, mass most likely to be focal oedema, fibrosis, hallmark: diffuse, uniform thickening of small bowel. Synonym: GVH disease. Acronym: GVHD (20 Sep 2002) |
| graft-versus-host response | <haematology> A common and serious, complication of bone marrow transplantation where there is a reaction of donated bone marrow against a patient's own tissue. When donor lymphocytes or a graft containing lymphocytes that are immunologically competent are given to a patient that has low immunological competence, an incompatibility reaction can result. This is due to antibodies from the donor against antigens in the host. This is due to mismatch of MHC Class I antigens and can produce lymphocyte clones that will react by a variety of processes against the host and cause damage. The clinical condition can be fatal and is due to the donor's immune cells recognising the host cells as foreign. The clinical entity characterised by anorexia, diarrhoea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the graft-versus-host reaction. It can occur in either chronic or acute forms and is treatable by immunosuppressive drugs. Seen most commonly following bone marrow transplantation, acute disease is seen after 5-40 days and chronic disease weeks to months after transplantation, affecting, principally, the gastrointestinal tract, liver, and skin. Radiological appearances of the gastrointestinal tract include; thickened wall, mucosal folds thickened or effaced, increased secretions most likely to be rapid transit of GI tract, mass most likely to be focal oedema, fibrosis, hallmark: diffuse, uniform thickening of small bowel. Synonym: GVH disease. Acronym: GVHD (20 Sep 2002) |
| grafter | 1. One who inserts scions on other stocks, or propagates fruit by ingrafting. 2. An instrument by which grafting is facilitated. 3. The original tree from which a scion has been taken for grafting upon another tree. Source: Websters Dictionary (01 Mar 1998) |
| grafting | 1. <botany> The act, art, or process of inserting grafts. 2. The act or method of weaving a cover for a ring, rope end, etc. 3. <surgery> The transplanting of a portion of flesh or skin to a denuded surface; autoplasty. 4. A scarfing or endwise attachment of one timber to another. <botany> Cleft grafting, a method of grafting by cutting the ends of the scion and stock completely across and obliquely, in such a manner that the sections are of the same shape, then lapping the ends so that the one cut surface exactly fits the other, and securing them by tying or otherwise. Whip grafting, tongue grafting, the same as splice grafting, except that a cleft or slit is made in the end of both scion and stock, in the direction of the grain and in the middle of the sloping surface, forming a kind of tongue, so that when put together, the tongue of each is inserted in the slit of the other. Grafting scissors, a surgeon's scissors, used in rhinoplastic operations, etc. Grafting tool. Any tool used in grafting. A very strong curved spade used in digging canals. Grafting wax, a composition of rosin, beeswax tallow, etc, used in binding up the wounds of newly grafted trees. Source: Websters Dictionary (01 Mar 1998) |