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Edlefsen's reagent An alkaline permanganate solution used in the determination of sugar in the urine.
(05 Mar 2000)
Edlefsen, Gustav <person> German physician, 1842-1910.
See: Edlefsen's reagent.
(05 Mar 2000)
edman degradation A lab technique used to find out the order of amino acids in a polypeptide (chain of amino acids). It involves using the Edman reagent, phenyl isothiocyanate (PITC), to react one by one with each amino acid, in order. The technique is used in machines which automatically sequence (determine the order of subunits) polypeptides.
(09 Oct 1997)
Edman method C6H5-N==C==S, a reagent that condenses with the free N-terminal amino group of a peptide chain to form a phenylthiohydantoin in the Edman method of identifying N-terminal amino acids.
Synonym: Edman's reagent.
Acronym: PITC
(05 Mar 2000)
Edman reagent Phenyl isothiocyanate. The classic method for sequence determination of peptides using sequential cleavage of the N terminal residue after reaction with Edman reagent. The N terminal amino acid is removed as a phenylthiohydantoin derivative.
(18 Nov 1997)
Edman's reagent C6H5-N==C==S, a reagent that condenses with the free N-terminal amino group of a peptide chain to form a phenylthiohydantoin in the Edman method of identifying N-terminal amino acids.
Synonym: Edman's reagent.
Acronym: PITC
(05 Mar 2000)
Edman, Pehr <person> Australian scientist, 1916-1977.
See: Edman method, Edman's reagent.
(05 Mar 2000)
EDn <pharmacology> This is the commonly used abbreviation for the dose of a toxicant causing a defined effect on n% of a test population, for instance, the ED50 would affect 50% of the population.
(13 Nov 1997)
EDRF <biochemistry> This compound is produced from L arginine by the enzyme nitric oxide synthase. Acts as a potent vasorelaxant via elevation of intracellular cGMP in vascular smooth muscle.
Synthesis of nitric oxide is not confined to endothelium, isoforms of nitric oxide synthase are also found in brain, neutrophils and platelets.
Synonym: endothelium derived relaxation factor.
Acronym: NO
(29 Dec 1997)
Edridge-Green lamp A lantern used to test recognition of coloured signals; it displays a single light with colour filters in rotating disks that can be modified to simulate conditions of weather and atmosphere. This test for colour blindness was officially adopted in Great Britain in 1915 in place of the Holmgren wool test, but is now seldom used.
(05 Mar 2000)
Edridge-Green, Frederick <person> English ophthalmologist, 1863-1953.
See: Edridge-Green lamp.
(05 Mar 2000)
edriophthalma <zoology> A group of Crustacea in which the eyes are without stalks; the Arthrostraca.
Alternative forms: Edriophthalmata.
Origin: NL, fr. Gr. Steadfast + the eye.
Source: Websters Dictionary
(01 Mar 1998)
edriophthalmous <zoology> Pertaining to the Edriophthalma.
Source: Websters Dictionary
(01 Mar 1998)
edrophonium <chemical> A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Pharmacological action: anti-arrhythmia agents, antidotes, cholinesterase inhibitor, parasympathomimetic.
Chemical name: Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-
(12 Dec 1998)
edrophonium chloride Dimethylethyl (3-hydroxyphenyl)ammonium chloride;a competitive antagonist of skeletal muscle relaxants (curare derivatives and gallamine triethiodide) and an anticholinesterase, used as an antidote for curariform drugs, as a diagnostic agent in myasthenia gravis, and in myasthenic crisis.
(05 Mar 2000)
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