| ECG | Electro-Cardio-Graphy(-Gram); 심전도 = EKG 1. Conducting System Structu... |
|---|---|
| MSP | Minute Sequence Pyelogram |
| RSP | Rapid Sequence IVP |
| aa seq | amino acid sequence |
| ABS | abdominal surgery; acute brain syndrome; Adaptive Behavior Scale; admitting blood sugar; adult bovin... |
| shine-dalgarno sequence | A short stretch of nucleotides on a prokaryotic mRNA molecule upstream of the translational start site, that serves to bind to ribosomal RNA and thereby bring the ribosome to the initiation codon on the mRNA. (09 Oct 1997) |
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| signal sequence | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signature sequence | Short oligonucleotides of unique sequence found in 16S ribosomal RNA of a particular group of prokaryotes. (09 Oct 1997) |
| disruption sequence | The events that occur when a foetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus. (12 Dec 1998) |
| insertion sequence | Mobile nucleotide sequences that occur naturally in the genomes of bacterial populations. When inserted into bacterial DNA, they inactivate the gene concerned, when they are removed the gene regains its activity. Closely related to transposons and range in size from a few hundred to a few thousand bases, but are usually less than 1500 bases. (18 Nov 1997) |
| intervening sequence | <molecular biology> Alternative but uncommon name for an intron. (18 Nov 1997) |
| tandem repeat sequence | <molecular biology> Multiple copies of the same base sequence on a chromosome, used as a marker in physical mapping. (09 Oct 1997) |
| termination sequence | <molecular biology> The three codons, UAA known as ochre, UAG as amber and UGA as opal, that do not code for an amino acid but act as signals for the termination of protein synthesis. They are not represented by any tRNA and termination is catalysed by protein release factors. There are two release factors in E. Coli, RF1 recognises UAA and UAG, RF2 recognises UAA and UGA. Eukaryotes have a single GTP requiring factor, eRF. See: ochre suppressor, amber suppressor. (13 Jan 1998) |
| enhancer sequence | <molecular biology> A nucleotide sequence, located as many as several thousand base pairs away in either direction from the target gene, which enhances transcription of that gene. (14 Nov 1997) |
| evolutionarily conserved sequence | A base sequence in a DNA molecule (or an amino acid sequence in a protein) that has remained essentially unchanged throughout evolution. (12 Dec 1998) |
| Expressed Sequence Tag | <molecular biology> Expressed sequence tags are sequence tagged sites derived from cDNAs. See: sequence tagged site. Acronym: EST (06 Aug 1998) |
| flanking sequence | <molecular biology> Short DNA sequences bordering a transcription unit. Often these do not code for proteins. (18 Nov 1997) |
| leader sequence | <molecular biology> In the regulation of gene expression for enzymes concerned with amino acid synthesis in prokaryotes, the leader sequence codes for the leader peptide that contains several residues of the amino acid being regulated. Transcription is closely linked to translation and if translation is retarded by limited supply of amino acyl tRNA for the specific amino acid, the mode of transcription of the leader sequence permits full transcription of the operon genes, otherwise complete transcription of the leader sequence prematurely terminates transcription of the operon. (18 Nov 1997) |
| A-DNA | A form of DNA in which the helix is right-handed and the overall appearance is short and broad. (05 Mar 2000) |
| a-form DNA | <molecular biology> One of several forms that can be assumed by a double helix. A-DNA is stable in dehydrated conditions. This form is less common than the dominant form found under physiological conditions -- beta-DNA. This form is also assumed by DNA-RNA hybrid helices and by regions of double-stranded RNA. It is a right-handed helix and is a more compact form than beta-DNA. (09 Oct 1997) |