Diphosphotransferases - ț̢
A class of phosphotransferases that catalyzes the transfer of diphosphate-containing groups. EC 2.7.6.
Synonyms :
Diphtheria - ț̢
A localized infection of mucous membranes or skin caused by toxigenic strains of CORYNEBACTERIUM DIPHTHERIAE. It is characterized by the presence of a pseudomembrane at the site of infection. DIPHTHERIA TOXIN, produced by C. diphtheriae, can cause myocarditis, polyneuritis, and other systemic toxic effects.
Synonyms : Diphtherias
Diphtheria Antitoxin - ț̢
An antitoxin produced against the toxin of CORYNEBACTERIUM DIPHTHERIAE that is used for the treatment of DIPHTHERIA.
Synonyms : Antitoxin, Diphtheria
Diphtheria Toxin - ț̢
An ADP-ribosylating EXOTOXIN produced by CORYNEBACTERIUM DIPHTHERIAE that causes the signs and symptoms of DIPHTHERIA. It can be broken into two unequal domains: the smaller, catalytic A domain is the lethal moiety and contains mono ADPribose transferase which transfers ADP RIBOSE to PEPTIDE ELONGATION FACTOR 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells.
Synonyms : Toxin, Corynebacterium Diphtheriae
Diphtheria Toxoid - ț̢
The formaldehyde-inactivated toxin of Corynebacterium diphtheriae. It is generally used in mixtures with TETANUS TOXOID and PERTUSSIS VACCINE; (DTP); or with tetanus toxoid alone (DT for pediatric use and Td, which contains 5- to 10-fold less diphtheria toxoid, for other use). Diphtheria toxoid is used for the prevention of diphtheria; DIPHTHERIA ANTITOXIN is for treatment. (From Dorland, 28th ed)