| nucleotide 3'-pyrophosphokinase-2',3'-cyclic monophosphokinase | <enzyme> Transfers 5'-beta,gamma-pyrophosphate from ATP and some ATP derivatives to nucleotides and nucleosides at the 3'-hydroxyl group; synthesises the respective 3'-pyrophosphoryl nucleotides Registry number: EC 2.7.6.- Synonym: ppkase (26 Jun 1999) |
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| dibutyryl cyclic GMP | <chemical> N-(1-oxobutyl)-cyclic 3',5'-(hydrogen phosphate)-2'-butanoate guanosine. A derivative of cyclic GMP. It has a higher resistance to extracellular and intracellular phosphodiesterase than cyclic GMP. Chemical name: Guanosine, N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate (12 Dec 1998) |
| inositol cyclic 1,2-phosphate 1-phosphodiesterase | <enzyme> Converts inositol 1:2-cyclic phosphate to inositol 2-phosphate; do not confuse with inositol 1,2 cyclic-phosphate 2-phosphohydrolase see annexin III Registry number: EC 3.1.4.- Synonym: cins(1,2)p hydrolase II (26 Jun 1999) |
| ethers, cyclic | Compounds of the general formula r-o-r arranged in a ring or crown formation. (12 Dec 1998) |
| 2',3'-cyclic nucleotide 2'-phosphodiesterase | <enzyme> Catalyses the hydrolysis of the 2'-phosphodiesterase bond to yield nucleoside 3'phosphate Registry number: EC 3.1.4.16 Synonym: 2',3'-cyclic nucleotide 2'-phosphohydrolase (26 Jun 1999) |
| 2',3'-cyclic nucleotide 3'-phosphodiesterase | <enzyme> Catalyses the hydrolysis of the 3'-phosphoesterase bond to yield nucleoside 2'-phosphate Registry number: EC 3.1.4.37 Synonym: 2',3'-cyclic nucleotide 3'-phosphohydrolase, 2',3'-cn phosphodiesterase, 2',3'-cnpase (26 Jun 1999) |
| 2',3'-cyclic-nucleotide phosphodiesterases | <enzyme> Nucleoside-2',3'-cyclic phosphate nucleotidohydrolase. Enzymes that catalyze the hydrolysis of the 2'- or 3'- phosphate bonds of 2',3'-cyclic nucleotides. Also hydrolyzes nucleoside monophosphates. Registry number: EC 3.1.4.- (12 Dec 1998) |
| 3',5'-cyclic-GMP phosphodiesterase | <enzyme> An enzyme that catalyses the hydrolysis of cyclic GMP to yield guanosine-5'-phosphate. Chemical name: 3',5'-Cyclic-GMP 5'-nucleotidohydrolase Registry number: EC 3.1.4.35 (12 Dec 1998) |
| 3',5'-cyclic-nucleotide phosphodiesterase | <enzyme> An enzyme that catalyses the hydrolysis of cyclic AMP to form adenosine 5'-phosphate. The enzyme is widely distributed in animal tissue and controls the level of intracellular cyclic AMP. Also acts on 3',5'-cyclic imp and 3',5'-cyclic GMP. Chemical name: 3',5'-Cyclic-nucleotide 5'-nucleotidohydrolase Registry number: EC 3.1.4.17 (12 Dec 1998) |
| 8-bromo cyclic adenosine monophosphate | <chemical> 8-bromoadenosine cyclic 3',5'-(hydrogen phosphate). A long-acting derivative of cyclic AMP. It is an activator of cyclic AMP-dependent protein kinase, but resistant to degradation by cyclic AMP phosphodiesterase. Chemical name: Adenosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate) (12 Dec 1998) |
| anamnestic response | <immunology> Archaic term now replaced by such terms as secondary immune response, immune memory. (18 Nov 1997) |
| audiometry, evoked response | A form of electrophysiologic audiometry in which an analog computer is included in the circuit to average out ongoing or spontaneous brain wave activity. A characteristic pattern of response to a sound stimulus may then become evident. Evoked response audiometry is known also as electric response audiometry. (12 Dec 1998) |
| auditory brainstem response audiometry | An electrophysiologic measure of auditory function utilizing responses produced by the auditory nerve and the brainstem to repetitive acoustic stimuli. (05 Mar 2000) |
| biological response modifier | <pharmacology, oncology> A substance used in adjuvant therapy that takes advantage of the bodys own natural defense mechanisms to inhibit the growth of a tumour. (16 Dec 1997) |
| biological response modifiers | Substances that stimulate the body's response to infection and disease. The body naturally produces small amounts of these substances. Scientists can produce some of them in the laboratory in large amounts and use them in cancer treatment. Also called BRMs. (12 Dec 1998) |