| sex chromosomes | The homologous chromosomes that are dissimilar in the heterogametic sex. There are the x chromosome, the y chromosome, and the w, z chromosomes (in animals in which the female is the heterogametic sex (the silkworm moth bombyx mori, for example). In such cases the w chromosome is the female-determining and the male is zz. (12 Dec 1998) |
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| nonhomologous chromosomes | <genetics> Chromosome's that are not members of the same pair. (05 Mar 2000) |
| double minute chromosomes | <genetics, molecular biology> Paired, extrachromosomal elements lacking centromeres, often associated with a drug resistance gene. (05 Mar 2000) |
| duplication of chromosomes | A chromosome aberration resulting from unequal crossing over or exchange of segments between two homologous chromosomes; one chromosome of the pair loses a small segment, while the other gains this segment; the chromosome gaining the segment has undergone duplication while its homologue has undergone deletion. See: haemoglobin Lepore. (05 Mar 2000) |
| inversion of chromosomes | A chromosome aberration resulting from a double break in a segment of the chromosome, with end for end rotation of the fragment between the fracture lines, and refusion of the fragments; this results in reversal of the order of genes in that segment. (05 Mar 2000) |
| yeast artificial chromosomes | Yeast DNA sequences that have incorporated into them very large foreign DNA fragments; the recombinant DNA is then introduced into the yeast by transformation; the use of yeast artificial chromosomes permits the cloning of large genes with their flanking regulatory sequences. (05 Mar 2000) |