| ¿µ¹® | hemolytic disease of newborn | ÇÑ±Û | ½Å»ý¾Æ¿ëÇ÷º´ |
|---|---|---|---|
| ¼³¸í | ½Å»ý¾Æ¿¡¼ ÀûÇ÷±¸°¡ ºñÁ¤»óÀûÀ¸·Î ¸¹ÀÌ ÆÄ±«µÇ´Â º´À¸·Î žÆÀû¸ð±¸Áõ(erythroblastosis fetalis)¿Í °°Àº ¶æÀ¸·Î ¾²ÀδÙ. À̰ÍÀº ¾î¸Ó´Ï¿¡°Ô¼ »ý»êµÈ ½Å»ý¾Æ³ª žÆÀÇ ÀûÇ÷±¸¿¡ ´ëÇÑ Ç×ü°¡ ŹÝÀ» °Ç³Ê¿Í¼ žÆÀÇ ÀûÇ÷±¸¿Í °áÇÕÇÏ¿©¼ »ý±â´Â ¿ëÇ÷¼ººóÇ÷À» À̸£´Â ¸». Áï ½Å»ý¾Æ³ª žÆÀÇ ÀûÇ÷±¸ÀÇ Ç×ü°¡ ¾î¸Ó´ÏÀÇ ¸ö¿¡¼ »ý»êÀÌ µÇ°í À̰ÍÀÌ Å¹ÝÀ» ÅëÇØ¼ žƿ¡°Ô ³Ñ¾î°¡¼ žÆÀÇ ÀûÇ÷±¸¿Í °áÇÕÀ» Çϰí ÀÌ Ç×ü¿Í °áÇÕÇÑ ÀûÇ÷±¸´Â ÆÄ±«°¡ µÇ¾î¼ ºóÇ÷ÀÌ »ý±ä °ÍÀ» žÆÀû¸ð±¸ÁõÀ̶ó°í ÇÑ´Ù. À̰ÍÀº Rh Àû¸ð±¸Áõ(Rh erythroblastosis)¿Í ABO Àû¸ð±¸Áõ(ABO erythroblastosis)·Î ³ª´ ¼ö°¡ ÀÖ´Ù. |
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| ¿µ¹® | coronary artery disease | ÇÑ±Û | ½ÉÀ嵿¸Æº´ |
|---|---|---|---|
| ¼³¸í | ½ÉÀ嵿¸ÆÀ̶õ ½ÉÀå¿¡ Ç÷¾×À» °ø±ÞÇÏ´Â µ¿¸ÆÀ» ¸»ÇÑ´Ù. ½ÉÀåµµ ´Ù¸¥ ±ÙÀ°°ú ¸¶Âù°¡Áö·Î Ç÷¾×À» °ø±Þ¹Þ¾Æ¾ß ¼öÃàÀ» ÇÒ ¼ö°¡ ÀÖ´Â ±â°üÀ¸·Î ½ÉÀåÀÇ Ç÷¾×À» °ø±ÞÇÏ´Â µ¿¸ÆÀ» ½ÉÀ嵿¸ÆÀ̶ó°í ÇÑ´Ù. ½ÉÀ嵿¸Æº´À̶õ ½ÉÀ嵿¸ÆÀÇ ³»°æÀÌ Á¼¾ÆÁ®¼ »ý±â´Â ÁúȯÀ¸·Î ÇãÇ÷½ÉÀ庴(ischemic heart disease)À̶ó°íµµ ºÒ¸°´Ù. °ü»óµ¿¸ÆÀÌ Á¼¾ÆÁú °æ¿ì¿¡´Â ½ÉÀåÀ¸·Î °¡´Â Ç÷¾×ÀÇ ¾çÀÌ Àû¾îÁ®¼ ½ÉÀå¿¡ ÃæºÐÇÑ Ç÷¾×ÀÌ °ø±ÞÀÌ µÇÁö ¸øÇϹǷΠ¿©·¯ °¡Áö º´ÀûÀÎ Çö»óÀÌ »ý±ä´Ù. ½ÉÀ嵿¸ÆÀÌ Á¼¾ÆÁö´Â µ¥¿¡´Â ¿©·¯ °¡Áö ¿øÀÎÀÌ ÀÖÀ» ¼ö°¡ ÀÖÀ¸³ª ÁÖ·Î ½ÉÀ嵿¸ÆÀÇ µ¿¸Æ°æÈÁõ¿¡ ÀÇÇÑ´Ù. µ¿¸Æ°æÈÁõÀ̶õ µ¿¸ÆÀÇ ³»Ãþ¿¡ Áö¹æ°ú ÄÝ·¹½ºÅ×·Ñ·Î ÀÌ·ç¾îÁø Á×Á¾(atheroma)°¡ »ý±â´Â ÁúȯÀ¸·Î Á×Á¾ÀÌ »ý±ä µ¿¸ÆÀº Á×Á¾ÀÌ Ç÷°üÀÇ ³»ºÎ·Î µ¹ÃâÇÏ°Ô µÇ¾î¼ Ç÷°üÀÇ ³»°æÀÌ ÀÛ¾ÆÁö°Ô µÈ´Ù. ½ÉÀ嵿¸Æº´Àº ±× Á¤µµ¿¡ µû¶ó¼ Çù½ÉÁõ(angina pectoris)¿Í ½É±Ù°æ»öÁõ(myocardial infarction)À¸·Î ³ª´«´Ù. Çù½ÉÁõÀº ½ÉÀ嵿¸ÆÀÇ ºÎºÐÀû Æó¼â¿¡ ÀÇÇØ¼ Æò»ó½Ã¿¡´Â Áõ»óÀÌ ¾øÁö¸¸ ½ÉÀåÀÌ ¸¹Àº Ȱµ¿À» ÇÒ °æ¿ì¿¡ ½ÉÀå¿¡ Çǰ¡ ÃæºÐÇÑ ¸¸Å °ø±ÞÀÌ µÇÁö ¾Ê¾Æ¼ »ý±â´Â Áúº´À¸·Î Æò»ó½Ã¿¡ ½¯ °æ¿ì¿¡´Â ¾Æ¹« Áõ»óÀÌ ¾øÁö¸¸ ¿îµ¿À̳ª °ú½Ä µîÀÇ ¿øÀÎÀ¸·Î ½ÉÀåÀÌ ¸¹Àº ¿îµ¿À» ÇÒ °æ¿ì¿¡ ½ÉÀå¿¡ °ø±ÞµÇ´Â Ç÷¾×ÀÇ ¾çÀÌ ¸ðÀÚ¶ó¼ Áõ»ó(´ë°³ °¡½¿ºÎÀ§¿¡ Áã¾îÂ¥´Â µíÇÑ ÅëÁõ)ÀÌ »ý±ä´Ù. ½É±Ù°æ»öÁõÀ̶õ ½ÉÀ嵿¸ÆÀÇ ¿ÏÀüÆó¼â¿¡ ÀÇÇØ¼ ½ÉÀåÀÇ ±ÙÀ°ÀÌ Ç÷¾×À» ÀüÇô °ø±Þ¹ÞÁö ¸øÇؼ ½ÉÀåÀÇ ±ÙÀ°ÀÌ ½â´Â °æ¿ì¸¦ ¸»ÇÑ´Ù. |
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| ¿µ¹® | heart disease | ÇÑ±Û | ½ÉÀ庴 |
|---|---|---|---|
| ¼³¸í | ¼øÈ¯±â Áúȯ Áß ½ÉÀåÀÇ º´. ÀϹÝÀûÀ¸·Î ½ÉÀåÇ÷°üÀ̳ª ½ÉÀåÀÇ º´µµ Æ÷ÇԵȴÙ. º´ÅÍÀÇ ºÎÀ§¿¡ ÀÇÇÑ º´¸®ÇغÎÇÐÀû ºÐ·ù¿Í º´Àο¡ ÀÇÇÑ ºÐ·ù°¡ ÀÖ´Ù. ÀüÀÚ´Â ¼ö ½Ê ³â ÀüºÎÅÍ ¾²¿©Á® ¿ÔÀ¸³ª ±Ù³â¿¡ ¿Í¼ º»ÁúÀûÀÎ ¿øÀοä¹ýÀÌ °¡´ÉÇÏ°Ô µÈ ÀÌÈÄ´Â ÈÄÀÚÀÇ ºÐ·ù°¡ ÀÇÀǰ¡ ÀÖ¾î¼ ¸¹ÀÌ ¾²ÀÌ°Ô µÇ¾ú´Ù. º´ÅÍ ºÎÀ§·Î´Â ½É³»¸·(ÆÇ¸·)-½ÉÀå±Ù-½ÉÀ帷, ±× ¹ÛÀÇ °ÍÀ» µé ¼ö ÀÖÀ¸¸ç, °¢°¢ ½É³»¸·¿°-½ÉÀåÆÇ¸·Áõ-½É±Ù¿°-½É±Ù°æ»ö-½ÉÀ帷¿°-¼±Ãµ¼º ½ÉÀ庴(½ÉÀå±âÇü) µîÀÌÆ÷ÇԵȴÙ. º´Àκ°¿¡¼´Â ½ÉÀå±âÇüÀ» ºñ·ÔÇÏ¿© ·ù¸¶Ä¡½º ½ÉÀ庴-¸Åµ¶¼º ½ÉÀ庴-°íÇ÷¾Ð¼º ½ÉÀ庴-½ÉÀ嵿¸Æ°æÈ¼º ½ÉÀ庴-Æó¼º½ÉÀå-¼¼±Õ¼º ½É³»¸·¿°-½ÉÀå½Å°æÁõ µîÀ¸·Î ³ª´©¾îÁö¸ç, ºÎÁ¤¸ÆÀ̳ª ¹æ½ÇÂ÷´Ü µîÀÇ ÀÚ±ØÀüµµ°èÀÇ Àå¾Ö¿¡ ÀÇÇÑ °Íµµ Áõ¼¼ÀÇ Çϳª·Î º¼ ¼ö ÀÖ´Ù. ½ÉÀ庴Àº ÀÚ°¢ÀûÀ¸·Î´Â ¹«Áõ¼¼ÀÎ °Í¿¡¼ºÎÅÍ ½ÉÀå±â´É»ó½Ç·Î È£Èí°ï¶õ±îÁö ÀÖ´Ù. |
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| ¿µ¹® | allergic disease | ÇÑ±Û | ¾Ë·¹¸£±âº´ |
|---|---|---|---|
| ¼³¸í | ³ÐÀº ¶æÀ¸·Î´Â IÇü, IIÇü, IIIÇü ¹× IVÇüÀÇ ¾Ë·¹¸£±â ¹ÝÀÀ¿¡ ÀÇÇØ¼ »ý±â´Â ¸ðµç º´À» °¡¸®Å²´Ù. ±×·¯³ª º¸Åë ¾Ë·¹¸£±âº´À̶ó°í Çϸé Á¼Àº ¶æÀ» °¡¸®Å°´Â °æ¿ì°¡ ¸¹°í, IÇüÀÇ ¾Ë·¹¸£±â¹ÝÀÀ¿¡ ÀÇÇØ¼ »ý±â´Â °ÍÀ» °¡¸®Å²´Ù. Áï ¾ÆÅäÇǺ´°ú ¸¶Âù°¡Áö ¶æÀ¸·Î ÇØ¼®µÇ´Â °æ¿ì°¡ ¸¹°í, ±â°üÁöõ½Ä, ¾Ë·¹¸£±âÄÚ¿°, ¾Ë·¹¸£±âÁ¡¸·¿°, µÎµå·¯±â, ¾Æ³ªÇʶô½Ã½º µîÀÌ ¿©±â¿¡ ¼ÓÇÑ´Ù. |
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| ¿µ¹® | Alzheimer's disease | ÇÑ±Û | ¾ËÃ÷ÇÏÀ̸Ӻ´ |
|---|---|---|---|
| ¼³¸í | ÅðÇ༺ ³úº´. ³ëÀο¡¼ÀÇ Ä¡¸ÅÀÇ ¿øÀÎ Áß °¡Àå ÈçÇÑ ÇüÅÂÀÌ´Ù. º´¸®Á¶Á÷ÇÐÀûÀ¸·Î´Â ³úÀÇ Àü¹ÝÀûÀÎ À§Ãà, ³ú½ÇÀÇ È®Àå, ½Å°æ¼¶À¯ÀÇ ´Ù¹ß¼º º´ÅÍ(½Å°æ¼¶À¯µÚƲ¸²)¿Í ³ëÀιÝ(neuritic plaque) µîÀÌ Æ¯Â¡ÀÌ´Ù. ÀÓ»óÀûÀΠƯ¡Àº Á¡ÁøÀûÀÎ ±â¾ï-ÆÇ´Ü-¾ð¾î´É·Â µî ÁöÀûÀÎ ±â´ÉÀÇ °¨Åð¿Í ÀÏ»ó»ýȰ´É·Â-ÀΰÝ-Çൿ¾ç»óÀÇ Àå¾ÖÀÌ´Ù. º´¿¡ °É¸®¸é Ãʱ⿡´Â À̸§-³¯Â¥-Àå¼Ò¿Í °°Àº °ÍµéÀÌ ±â¾ï¿¡¼ »ç¶óÁö°í, ½ÉÇØÁö¸é ÈÀå½ÇÀ» °¡°Å³ª ¿ä¸®¸¦ Çϰųª ½ÅÀ» ½Å´Â ÀÏ µîÀÇ ÀÏ»ó»ýȰÁ¶Â÷µµ ÀØ°Ô µÈ´Ù. µ¿½Ã¿¡ ¿ì¿ïÁõ¼¼³ª ÀΰÝÀÇ È²Æó, °ÝÇÑ Çൿ µîÀÇ Á¤½ÅÀÇÇÐÀûÀÎ Áõ¼¼µµ µ¿¹ÝµÈ´Ù. ÀÌ·¯ÇÑ Áõ¼¼µéÀÌ Á¡ÀüÀûÀ¸·Î ÁøÇàµÇ¾î °á±¹Àº Á×À½¿¡ À̸£°Ô µÈ´Ù. ¹ßº´ ÈÄ ¼¼È÷ Á×À½¿¡ À̸£´Â ±â°£Àº 6~8³â Á¤µµÀÌÁö¸¸ »ç¶÷¿¡ µû¶ó 20³âÀÌ ³Ñ´Â °æ¿ìµµ ÀÖ´Ù. |
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| CRD | carbohydrate-recognition domain; chronic renal disease; chronic respiratory disease; child restraint... |
|---|---|
| DF | decapacitation factor; decontamination factor; deferoxamine; deficiency factor; defined flora [anima... |
| GRF | gastrin-releasing factor; genetically related macrophage factor; gonadotropin-releasing factor; grow... |
| HSF | heat shock factor; hepatocyte stimulatory factor; histamine sensitizing factor; human serum esterase... |
| LPF | leukocytosis-promoting factor; leukopenia factor; lipopolysaccharide factor; localized plaque format... |
D factor
| galactagogue factor | <endocrinology> A factor in extracts of the posterior lobe of the hypophysis that, by stimulating the smooth muscle of the lobulo-alveolar system of the mammary gland, causes a flow of milk from the nipple. (05 Mar 2000) |
|---|---|
| galactopoietic factor | <protein> Pituitary lactogenic hormone (23 kD) Synthesised on endoplasmic reticulum bound ribosomes as preprolactin that has an N terminal signal peptide that is cleaved from the mature form. The conversion of preprolactin to prolactin has been much used as an assay for membrane insertion. (18 Nov 1997) |
| macrophage-activating factor | An agent that stimulates macrophages to attack and ingest cancer cells. They are secreted by stimulated lymphocytes that prime macrophages to become non-specifically cytotoxic to tumours. They also modulate the expression of macrophage cell surface ia antigens. One maf is interferon-gamma (interferon type II). Other factors antigenically distinct from ifn-gamma have also been identified. (12 Dec 1998) |
| macrophage colony-stimulating factor | <growth factor> A glycoprotein growth factor that causes the committed cell line to proliferate and mature into macrophages. A cytokine synthesised by mesenchymal cells that stimulates pluripotent stem cells of bone marrow into differentiating towards the production of monocytes (mononuclear phagocytes). The compound stimulates the survival, proliferation, and differentiation of haematopoietic cells of the monocyte-macrophage series. It is a disulfide-bonded glycoprotein dimer with a mw of 70 kD and binds to a single class of high affinity receptor which is identical to the product of the c-fms proto-oncogene. See: colony-stimulating factors. Chemical name: Colony-stimulating factor 1 Acronym: M-CSF (12 Dec 1998) |
| macrophage inhibition factor | <cytokine> A group of lymphokines (including a 14 kD glycoprotein) produced by activated T lymphocytes that reduces macrophage mobility and probably increases macrophage macrophage adhesion. (18 Nov 1997) |
| radiation weighting factor | In radiation protection, a factor weighting the absorbed dose of radiation of a specific type and energy for its effect on tissue. See: equivalent dose. (05 Mar 2000) |
| maise factor | <molecular biology, plant biology> A naturally occurring cytokinin, originally isolated from maize seeds. Its riboside is also a cytokinin. (18 Nov 1997) |
| vascular endothelial growth factor | A growth factor that is responsible for the growth of blood vessels. (12 Dec 1998) |
| mammotropic factor | <protein> Pituitary lactogenic hormone (23 kD) Synthesised on endoplasmic reticulum bound ribosomes as preprolactin that has an N terminal signal peptide that is cleaved from the mature form. The conversion of preprolactin to prolactin has been much used as an assay for membrane insertion. (18 Nov 1997) |
| receptors, atrial natriuretic factor | Cell surface proteins that bind atrial natriuretic factor with high affinity and trigger intracellular changes influencing the behaviour of cells. (12 Dec 1998) |
| receptors, colony-stimulating factor | Cell surface receptors for colony-stimulating factors, local mediators, and hormones that regulate the survival, proliferation, and differentiation of haemopoietic cells. (12 Dec 1998) |
| receptors, epidermal growth factor-urogastrone | Glycoproteins of about 170 kD that have protein kinase activity and span the plasma membranes of growing cells, including tumours. They are activated by the binding of epidermal growth factor-urogastrone which then initiates DNA and protein synthesis. They are not found on mitotically quiescent cells except in the stomach where they control the synthesis and release of digestive enzymes and gastric acid. Transforming growth factor alpha also binds to and activates these receptors. (12 Dec 1998) |
| receptors, fibroblast growth factor | Specific molecular sites or structures on cell membranes that react with fibroblast growth factors (both the basic and acidic forms), their analogs, or their antagonists to elicit or to inhibit the specific response of the cell to these factors. These receptors frequently possess tyrosine kinase activity. (12 Dec 1998) |
| receptors, granulocyte-colony-stimulating factor | Receptors that bind and internalise granulocyte-colony-stimulating factor. Their mw is believed to be 150 kD. These receptors are found mainly on a subset of myelomonocytic cells. (12 Dec 1998) |
| receptors, granulocyte-macrophage colony-stimulating factor | Receptors that bind and internalise the granulocyte-macrophage stimulating factor. Their mw is believed to be 84 kD. The most mature myelomonocytic cells, specifically human neutrophils, macrophages, and eosinophils, express the highest number of affinity receptors for this growth factor. (12 Dec 1998) |
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