| cold-rigor point | The degree of lowered temperature at which the activity of a cell ceases and the cell passes into the narcotic or hibernating state. (05 Mar 2000) |
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| cold sensitive enzyme | <enzyme> An enzyme that loses its stability as the temperature is lowered. (05 Mar 2000) |
| cold-sensitive mutant | A mutant that is defective at low temperature but functional at normal temperature. Compare: temperature-sensitive mutant. (05 Mar 2000) |
| cold sore | <dermatology, virology> An infection of the lips or mouth which results in a blistery sore that is caused by Herpes simplex type 1. Painful blisters (eventually becoming ulcers) will often presenting on the lips or nasal mucosa. Infected individuals should avoid contact with others due to potential for transfer of the infection. Herpes labialis tends to be recurrent and often exacerbated by stress, sunlight, fever or illness. Treatment includes the use of antiviral creams (acyclovir) and oral medications (acyclovir). Pre-treatment with oral acyclovir, in those prone to cold sores (prior to sun exposure, etc.) has been shown to decrease exacerbations. (27 Sep 1997) |
| cold spleen lesion | <radiology> Infarction, lymphoma, haematoma, tumour, splenic artery aneurysm, pancreatic pseudocyst, variant, artifact, absent spleen, splenectomy, sickle cell disease, trauma see: liver-spleen scan (12 Dec 1998) |
| cold stage | The stage of chill in a malarial paroxysm. (05 Mar 2000) |
| cold thyroid nodule | <radiology> Adenoma (75%), colloid cyst (10%), carcinoma (15%), mnemonic: CATCH PALLM colloid cyst, adenoma, thyroiditis, carcinoma, haematoma, parathyroid adenoma, abscess, lymph node, lymphoma, metastasis thyroid carcinoma, hot thyroid nodule (12 Dec 1998) |
| cold ulcer | A small gangrenous ulcer on the extremities; due to defective circulation. (05 Mar 2000) |
| cold urticaria | Wheal formation that develops after exposure to lowered temperatures, with or without demonstrable passive-transfer antibodies. Synonym: congelation urticaria. (05 Mar 2000) |
| cold virus | Any of the numerous strains of virus aetiologically associated with the common cold, chiefly the rhinoviruses, but also strains of adenovirus, Coxsackievirus, ECHO virus, and parainfluenza virus. Synonym: cold virus. (05 Mar 2000) |
| common cold | A viral upper respiratory tract infection. A contagious illness caused by a number of different types of viruses. Because of the great number of viruses that can cause a cold, the body never builds up resistance (immune) against all of them. For this reason, colds are a frequent and recurring problem. In fact, preschool children average 9 colds a year; those in kindergarten, 12 colds a year; and adolescents and adults, 7 colds per year. Going out into the cold weather has no effect on the spread of a cold. Antibiotics do not help the common cold. (12 Dec 1998) |
| common cold virus | Any of the numerous strains of virus aetiologically associated with the common cold, chiefly the rhinoviruses, but also strains of adenovirus, Coxsackievirus, ECHO virus, and parainfluenza virus. Synonym: cold virus. (05 Mar 2000) |
| haemagglutinating cold autoantibody | A cold autoagglutinin. (05 Mar 2000) |
| Salisbury common cold viruses | Strains of rhinovirus of historical interest because of early studies that established the viral aetiology of common colds. (05 Mar 2000) |
| Donath-Landsteiner cold autoantibody | An autoantibody of the IgG class responsible for paroxysmal cold haemoglobinuria; it is adsorbed to red cells only at temperatures of 20캜 or lower, causing the red cells to lyse in the presence of complement at higher temperatures; it has only slight agglutinating properties in spite of its marked lytic activity, and has a specificity within the blood group P; it is also occasionally present for short periods of time following measles and other infections, and formerly was frequently associated with syphilis. Synonym: cold haemolysin. (05 Mar 2000) |