| alpha-aminoadipic acid | 2-amino-1,6-hexanedioic acid;an intermediate of lysine biosynthesis in higher fungi and bacteria, but not in algae and higher plants. Also in degradation of lysine in mammals. (05 Mar 2000) |
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| alpha-aminoadipyl-cysteinyl-valine synthetase | <enzyme> As of 9/27/95 this has been separated from isopenicillin n synthetase Registry number: EC 6.3.2.- Synonym: acv synthetase, aa-cysteine synthetase, delta-(alpha-aminoadipyl)-cys-val synthetase, delta-(l-alpha-aminoadipyl)-l-cyteinyl-d-valine synthetase, pcbab gene product, acva gene product (26 Jun 1999) |
| alpha-amino-beta-ketoadipic acid | 2-Amino-3-oxo-1,6-hexanedioic acid;an intermediate of porphobilinogen synthesis formed by d-aminolevulinic acid synthase from succinyl-CoA and glycine; it rapidly decarboxylates to d-aminolevulinic acid. (05 Mar 2000) |
| alpha-aminoglutaric acid | <amino acid> One of the 20 _ amino acids commonly found in proteins. Plays a central role in amino acid metabolism, acting as precursor of glutamine, proline and arginine. Also acts as amino group donor in synthesis by transamination of alanine from pyruvate and aspartic acid from oxaloacetate. Glutamate is also a neurotransmitter, the product of its decarboxylation is the inhibitory neurotransmitter amino butyrate (GABA). (18 Nov 1997) |
| alpha-aminoisobutyric acid | 2-amino-2-methylpropionic acid;a synthetic amino acid useful in the study of amino acid transport across cell membranes and in the study of cytokine effects; it is not metabolised by the cell. (05 Mar 2000) |
| alpha-aminosuccinic acid | <amino acid> One of the twenty naturally occurring amino acids. Has the following chemical characteristics: pKa1 pKa2 pKa3 pI Water Solubility (30deg C)2.09-3.86 9.82 2.97 0.6 (09 Oct 1997) |
| alpha-amylase | <enzyme> An enzyme that catalyses the endohydrolysis of 1,4-alpha-glycosidic linkages in starch, glycogen, and related polysaccharides and oligosaccharides containing 3 or more 1,4-alpha-linked d-glucose units. Pharmacological action: anti-inflammatory agents. Chemical name: 1,4-alpha-D-Glucan glucanohydrolase Registry number: EC 3.2.1.1 (12 Dec 1998) |
| alpha angle | The angle between the visual and optic axes as they cross at the nodal point of the eye, the angle between the visual line and the major axis of the corneal ellipse. (05 Mar 2000) |
| alpha-antitrypsin deficiency | <enzyme> A specific enzyme (alpha 1 antitrypsinase) that when absent genetically can result in panacinar emphysema (lung disease) and liver disease. There is no specific treatment for this condition other than supportive care for the liver and lung complications. Medications such as alpha-1proteinase inhibitor is given regularly to these patients. Incidence: approximately 1 in 10,000. (02 Jan 1998) |
| alpha,beta-ketoalkene reductase | <enzyme> Nadh is much less effective than NADPH; catalyses the reduction of the carbon-carbon double bond of five membered ring cpds which have two conjugated carbonyl groups on both sides of a double bond Registry number: EC 1.3.1.- Synonym: n-ethylmaleimide reducing enzyme, NADPH-linked alpha,beta-ketoalkene double bond reductase, n-ethylmaleimide reductase (26 Jun 1999) |
| alpha-blocker | An agent that competitively blocks alpha-adrenergic receptors; used in the treatment of hypertension. Synonym: alpha-blocker. (05 Mar 2000) |
| alpha blocking | The attenuation of the occipital alpha rhythm (8-14 Hz brain waves as seen on an electroencephalogram), produced by opening the eyes or by intense mental concentration. (05 Mar 2000) |
| alpha cell | <biology> A type of cell in the pancreas (in areas called the islets of Langerhans). Alpha cells make and release a hormone called glucagon, which raises the level of glucose (sugar) in the blood. (09 Oct 1997) |
| Alpha cells | Alpha cell's of pancreas or of anterior lobe of hypophysis. (05 Mar 2000) |
| alpha cells of anterior lobe of hypophysis | Acidophil cell's that constitute about 35% of the cell's of the anterior lobe. There are two varieties: one that elaborates somatotropin, another that elaborates prolactin. (05 Mar 2000) |