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3-dehydrosphinganine reductase <enzyme> Reduces 3-ketosphingosine (3-dehydrosphinganine) to dihydrosphingosine (sphinganine)
Registry number: EC 1.1.1.102
Synonym: 3-oxosphinganine reductase
(26 Jun 1999)
3-deoxy-D-glycero-2,5-hexodiulosonate dehydrogenase <enzyme> Forms 2-keto-3-deoxy-d-gluconate from 3-deoxy-d-glycero-2,5-hexodiulosonate; uses NADH
Registry number: EC 1.1.1.127
Synonym: 2-keto-3-deoxygluconate oxidoreductase, ketodeoxyuronate dehydrogenase, 2-dehydro-3-deoxy-d-gluconate 5-dehydrogenase NADP+
(26 Jun 1999)
3-deoxy-manno-octulosonate cytidyltransferase <enzyme> Catalyzed the formation of cmp-kdo from ctp and kdo; k-cks is encoded by kpsu and participates in k5 polysaccharide expression
Registry number: EC 2.7.7.38
Synonym: cmp-kdo synthetase, ctp-cmp-3-deoxy-d-manno-octulosonate cytidylyltransferase, k-cks synthetase, kpsu gene product, kdsb gene product
(26 Jun 1999)
3-deoxy-manno-octulosonate-8-phosphatase <enzyme> Kdo-8-phosphate yields kdo + inorganic phosphate
Registry number: EC 3.1.3.45
Synonym: 2-keto-3-deoxyoctonate-8-phosphate phosphatase, kdo-8-phosphatase, 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
(26 Jun 1999)
3-glycerophosphate dehydrogenase <enzyme> Ubiquinone acts as hydrogen acceptor; for fad-dependent enzyme see EC 1.1.3.21
Registry number: EC 1.1.99.5
Synonym: l-3-glycerophosphate dehydrogenase
(26 Jun 1999)
3-hydroxy-2-methylpropionyl-CoA dehydrogenase <enzyme> Forms methylmalonyl-CoA saemialdehyde
Registry number: EC 1.1.1.-
Synonym: 3-hydroxyisobutyryl-CoA dehydrogenase
(26 Jun 1999)
3-hydroxy-2-pyrrolidinecarboxylic acid A derivative of proline found in certain collagens, particularly basement membrane collagen.
Synonym: 3-hydroxy-2-pyrrolidinecarboxylic acid.
(05 Mar 2000)
3-hydroxy-3-methylglutaryl-CoA -OOCCH2C(OH)(CH3)CH2COS-CoA;a key intermediate in the synthesis of ketone bodies and of steroids.
Synonym: 3-hydroxy-3-methylglutaryl-CoA.
Beta-hydroxy-beta-methylglutaryl-lyase, an enzyme, found primarily in liver and rumen epithelium that catalyses the formation of acetyl-CoA and acetoacetate from beta-hydroxy-beta-methylglutaryl-CoA; a key step in ketogenesis; a deficiency of this enzyme leads to episodes of severe metabolic acidosis without ketosis.
Beta-hydroxy-beta-methylglutaryl-reductase, an enzyme that catalyses the rate-limiting step of cholesterol biosynthesis, beta-hydroxy-beta-methylglutaryl-CoA + 2NADPH + 2H+ &rarr; mevalonate + 2NADP+ + coenzyme A.
Beta-hydroxy-beta-methylglutaryl-synthase, an enzyme in mitochondria that catalyses the reaction of acetyl-CoA with acetoacetyl-CoA and water to form beta-hydroxy-beta-methylglutaryl-CoA and coenzyme A, a step required for both ketogenesis and steroidogenesis to occur.
(05 Mar 2000)
3-hydroxy-4-oxoquinoline oxygenase <enzyme> Forms n-formylanthranilic acid + co2; 24 amino acids of n-terminal sequence given in first source
Registry number: EC 1.13.12.-
Synonym: 1h-3-hydroxy-4-oxoquinoline oxygenase, 3-oh-4-oxoquinoline oxygenase
(26 Jun 1999)
3-hydroxyacyl CoA dehydrogenases <enzyme> Enzymes that reversibly catalyze the oxidation of a 3-hydroxyacyl CoA to 3-ketoacyl CoA in the presence of NAD. They are key enzymes in the oxidation of fatty acids and in mitochondrial fatty acid synthesis.
Chemical name: (S)-3-Hydroxyacyl-CoA:NAD+ oxidoreductase
Registry number: EC 1.1.1.35
(12 Dec 1998)
3-hydroxyacyl-CoA dehydrogenase Beta-Hydroxyacyl dehydrogenase;enzyme catalyzing the oxidation of an l-3-hydroxyacyl-CoA to a 3-ketoacyl-CoA with reduction of NAD+; one of the enzymes of the b oxidation of fatty acids.
Synonym: beta-ketohydrogenase, beta-ketoreductase.
(05 Mar 2000)
3-hydroxyanthranilate 3,4-dioxygenase <enzyme> Chemical name: 3-hydroxyanthranilic acid oxygenase
Registry number: EC 1.13.11.6
Synonym: 3-hydroxyanthranilic acid oxygenase, 3-haa oxygenase
(26 Jun 1999)
3-hydroxyanthranilate-4-methyltransferase <enzyme> 36,000 da protein from streptomyces antibioticus that catalyses the transfer of a methyl group from s-adenosylmethionine to 3-hydroxyanthranilic acid.
Registry number: EC 2.1.1.-
Synonym: 3-haa-4-mt
(26 Jun 1999)
3-hydroxyanthranilic acid <chemical> 3-hydroxyanthranilic acid. An oxidation product of trytophan metabolism. It may be a free radical scavenger and a carcinogen.
Pharmacological action: carcinogens, free radical scavengers.
Chemical name: Benzoic acid, 2-amino-3-hydroxy-
(12 Dec 1998)
3-hydroxyanthranilic acid oxidase <enzyme> Catalyses the oxidation of 3-hydroxyanthranilate to 1,2-benzoquinoneimine-3-carboxylate in presence of molecular oxygen
Registry number: EC 1.10.3.5
(26 Jun 1999)
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