| immunoglobulin variable region | That region of the immunoglobulin (antibody) molecule that varies in its amino acid sequence and composition, confers the antigenic specificity, and is thought to comprise the binding site for the antigen. It is located at the n-terminus of the fab fragment of the immunoglobulin. It includes hypervariable and framework regions, vh family subgroups, and the complementarity-determining region. (12 Dec 1998) |
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| independent variable | A characteristic being measured or observed that is hypothesised to influence another event or manifestation (the dependent variable) within a defined area of relationships under study; that is, the independent variable is not influenced by the event or manifestation, but may cause it or contribute to its variation. See: dependent variable. (05 Mar 2000) |
| intermediate variable | A variable in a causal pathway that causes variation in the dependent variable and is itself caused to vary by the independent variable. (05 Mar 2000) |
| intervening variable | An event, such as an attitude or emotion, inferred to occur within an organism between the stimulation and response in such a way as to influence or determine the response. (05 Mar 2000) |
| anal orifice | <anatomy> The distal or terminal orifice of the alimentary canal. (18 Nov 1997) |
| aortic orifice | The opening from the left ventricle into the ascending aorta; it is guarded by the aortic valve. Synonym: ostium aortae, aortic ostium. (05 Mar 2000) |
| cardiac orifice | The trumpet-shaped opening of the oesophagus into the stomach. Synonym: ostium cardiacum, cardiac opening, oesophagogastric orifice. (05 Mar 2000) |
| vaginal orifice | The narrowest portion of the canal, in the floor of the vestibule posterior to the urethral orifice. Synonym: ostium vaginae, orificium vaginae, vaginal opening. (05 Mar 2000) |
| gastroduodenal orifice | The opening between the stomach and the superior part of the duodenum. Synonym: ostium pyloricum, gastroduodenal orifice. (05 Mar 2000) |
| golf-hole ureteral orifice | A retracted funnel-shaped condition of the ureteral orifice in the wall of the bladder, due often to tuberculosis or a secondary sclerosis of the ureter. (05 Mar 2000) |
| root canal orifice | An opening in the pulp chamber leading to the root canal. (05 Mar 2000) |
| mitral orifice | An atrioventricular opening which leads from the left atrium into the left ventricle of the heart. Synonym: ostium atrioventriculare sinistrum, ostium arteriosum. (05 Mar 2000) |
| pulmonary orifice | The opening of the pulmonary trunk from the right ventricle, guarded by the pulmonary valve. Synonym: ostium trunci pulmonalis, pulmonary orifice. (05 Mar 2000) |
| pyloric orifice | The opening between the stomach and the superior part of the duodenum. Synonym: ostium pyloricum, gastroduodenal orifice. (05 Mar 2000) |
| ileocaecal orifice | The opening of the terminal ileum into the large intestine at the transition between the caecum and the ascending colon. Synonym: ostium ileocaecale, ileocaecal opening. (05 Mar 2000) |
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