| haemolytic disease of the newborn | Abnormal breakup of red blood cells in the foetus or newborn. This is usually due to antibodies made by the mother directed against the baby's red cells. It is typically caused by rh incompatibility, that is differences between the mother and baby uinvolving the rh blood group. (12 Dec 1998) |
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| haemolytic gas | A poisonous gas, such as arsine, inhalation of which causes haemolysis with haemoglobinuria, jaundice, gastroenteritis, and nephritis. (05 Mar 2000) |
| haemolytic jaundice | <haematology> Haemolytic jaundice is a type of jaundice, where the skin takes on a yellowish hue, which occurs when red blood cells have been destroyed (by haemolysis). (09 Oct 1997) |
| haemolytic plaque assay | <investigation> A haemolytic plaque assay is a lab technique used to show that certain antibodies are secreted by antibody-making cells when these cells are mixed with red blood cells. The mixture is spread onto a plate of agar, if a plaque appears, it means that the red blood cells have been destroyed (by haemolysis) by the antibodies. (09 Oct 1997) |
| haemolytic splenomegaly | Splenomegaly associated with congenital haemolytic jaundice. (05 Mar 2000) |
| haemolytic streptococci | Those that produce active haemolysins (O and S) which cause a zone of clear haemolysis on the blood agar medium in the area of the colony; beta-haemolytic streptococci are divided into groups (A to O) on the basis of cell wall C carbohydrate (see Lancefield classification); Group A (in the strains pathogenic for man) comprises more than 50 types (designated by Arabic numerals) determined by cell wall M protein, which seems to be associated closely with virulence and is produced chiefly by strains with matt or mucoid colonies, in contrast to nonvirulent, glossy colony-producing strains; other surface protein antigens such as R and T (T substance), and the nucleoprotein fraction (P substance) seem to be of less importance. The more than 20 extracellular substances elaborated by strains of beta-haemolytic streptococci include erythrogenic toxin (elaborated only by lysogenic strains), deoxyribonuclease (streptodornase), haemolysins (streptolysins O and S), hyaluronidase, and streptokinase. Synonym: haemolytic streptococci. (05 Mar 2000) |
| haemolytic system | <haematology> A haemolytic system is composed of red blood cells covered with antibodies which are genetically identical to the surface proteins (antigens) of the red blood cells. It is used to measure how much complement is left after a round of complement fixation. (09 Oct 1997) |
| haemolytic unit | The smallest quantity (highest dilution) of inactivated immune serum (haemolysin) that will sensitise the standard suspension of erythrocytes so that the standard complement will cause complete haemolysis. Synonym: amboceptor unit. (05 Mar 2000) |
| haemolytic uraemic syndrome | <haematology, syndrome> A pathologic condition with involves the rupture (haemolysis) of red blood cells, subsequent anaemia, low platelet count and kidney failure. It is a syndrome of haemolytic anaemia, thrombocytopenia, and acute renal failure, with pathological finding of thrombotic microangiopathy in kidney and renal cortical necrosis. See: haemolytic anaemia. (12 Dec 1998) |
| disease, haemolytic, of the newborn | Abnormal breakup of red blood cells in the foetus or newborn. (12 Dec 1998) |
| aberrant haemoglobin | A mutant Hb that functions abnormally. Compare: variant haemoglobin. (05 Mar 2000) |
| bile pigment haemoglobin | <protein> A protein which is formed from the breakdown of haemoglobin (a protein that carries oxygen in the blood) and is a precursor to the bile pigment biliverdin. (09 Oct 1997) |
| carbon monoxide haemoglobin | <chemical> Chemical name: Haemoglobins, carbonyl- (12 Dec 1998) |
| variant haemoglobin | A harmless mutant form of Hb. (05 Mar 2000) |
| reduced haemoglobin | The form of Hb in red blood cells after the oxygen of oxyhemoglobin is released in the tissues. (05 Mar 2000) |