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islet cell antigen-related protein-tyrosine phosphatase <enzyme> Receptor-like autoantigen found in insulin-dependent diabetes; genbank l76258
Registry number: EC 3.1.3.-
Synonym: iar ptp
(26 Jun 1999)
T-cell protein tyrosine phosphatase <enzyme> Contains a single ptp domain and possesses a c-terminal region that may play a role in enzymatic regulation and/or targeting to discrete intracellular sites; amino acid sequence known
Registry number: EC 3.1.3.-
Synonym: tc-ptp
(26 Jun 1999)
TCK receptor-tyrosine kinase <enzyme> A member of the eph receptor tyrosine kinase subfamily; expressed during xenopus development; shows 79% amino acid identity to hek2; genbank l43621
Registry number: EC 2.7.1.-
Synonym: tck protein
(26 Jun 1999)
Tec protein-tyrosine kinase <enzyme> Member of the cytoplasmic ptks of the non-src family; associates with lyn ptk; n-terminal amino acid sequence given in first source
Registry number: EC 2.7.1.-
Synonym: tec ptk, tec kinase, tec tyrosine kinase
(26 Jun 1999)
TIE-2 receptor tyrosine kinase <enzyme> Expressed in developing vascular endothelial cells; unlike tie-1, also expressed in lens epithelium and heart epicardium; has the same organization of amino acid sequence motifs characteristic of tie-1; aa sequence of the intracellular and extracellular regions of tie-1 and tie-2 are 79% and 32% identical, respectively; aa sequence of both kinases given in first source
Registry number: EC 2.7.10.-
Synonym: tie-2-rtk
(26 Jun 1999)
tie receptor tyrosine kinase <enzyme> From human leukaemia cells; expressed in developing vascular endothelial cell; has homology with egf, bfgf, csf-1, pdgf and stem cell factor receptors; ligand and biologic function not known as of 12/92; tie-1 receptor tyrosine kinase is rat homolog of tie receptor tyrosine kinase; aa sequence known
Registry number: EC 2.7.10.-
Synonym: tie-1 receptor tyrosine kinase, tie-1 rtk
(26 Jun 1999)
emb protein-tyrosine kinase <enzyme> Isolated from murine mast cells
Registry number: EC 2.7.1-
Synonym: emb ptk
(26 Jun 1999)
emt protein-tyrosine kinase <enzyme> Isolated from murine mast cells
Registry number: EC 2.7.1.-
Synonym: emt ptk, itk protein, itk gene product, tsk protein, inducible t cell kinase
(26 Jun 1999)
epidermal growth factor receptor protein-tyrosine kinase <enzyme> The catalytic protein-tyrosine kinase domain found on the cytoplasmic beta-portion of epidermal growth factor receptor.
Registry number: EC 2.7.1.-
(12 Dec 1998)
estradiol receptor tyrosine kinase <enzyme> Calcium and calmodulin dependent
Registry number: EC 2.7.1.-
Synonym: ertk
(26 Jun 1999)
tubulin-tyrosine ligase <enzyme> An enzyme that covalently links a tyrosine to the C-terminal glutamyl residue of tubulin, coupled with the hydrolysis of ATP to ADP and Pi; this is a unique posttranslational modification that may have a significant role in cytoskeletal traffic and design.
(05 Mar 2000)
tyrosine <amino acid> One of the twenty amino acids directly coded in proteins. Nonessential in humans since can be synthesised from phenylalanine.
(18 Nov 1997)
tyrosine 3-monooxygenase <enzyme> An enzyme that catalyses the conversion of l-tyrosine, tetrahydrobiopterin, and oxygen to 3,4-dihydroxy-l-phenylalanine, dihydrobiopterin, and water.
Chemical name: L-Tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)
Registry number: EC 1.14.16.2
(12 Dec 1998)
tyrosine aminotransferase <enzyme> An enzyme that catalyses the reversible reaction of l-tyrosine and alpha-ketoglutarate producing p-hydroxyphenylpyruvate and l-glutamate; this enzyme catalyses a step in l-phenylalanine and l-tyrosine catabolism; a deficiency of this enzyme is associated with tyrosinaemia II.
Synonym: tyrosine transaminase.
(05 Mar 2000)
tyrosine decarboxylase <enzyme> A pyridoxal-phosphate protein that catalyses the conversion of l-tyrosine to tyramine and carbon dioxide. The bacterial enzyme also acts on 3-hydroxytyrosine and, more slowly, on 3-hydroxyphenylalanine.
Chemical name: L-Tyrosine carboxy-lyase
Registry number: EC 4.1.1.25
(12 Dec 1998)
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