| tumor necrosis factor |
A cytokine produced by many cell types that causes cytolysis of tumor cells, and mediates the expression of genes involved in the defense against disease.
출처: www.genpromag.com/Glossary~LETTER~T.html
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| tumor |
Abnormal growth or swelling; term often used to designate cancer.
출처: www.peteducation.com/dict_alpha_listing.cfm
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| tumor necrosis factor |
A cytokine, produced by macrophages, which helps activate T cells. It may also stimulate HIV activity. TNF levels are very high in persons with HIV, and the molecule is suspected to play a part in HIV-related wasting, neuropathy, and dementia. TNF triggers a biochemical pathway that leads to the programmed form of cell suicide known as apoptosis. It also activates a key molecule that can block this very pathway, and so set up a delicate life-death balance within the cell.
출처: www.amfar.org/cgi-bin/iowa/bridge.html
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| tumor suppressor gene |
a gene found normally in cells, which contributes to tumor development when both copies of the gene are deleted or inactivated. The name is derived from their normal function which would block tumor development.
출처: www.uvm.edu/~cgep/Education/Glossary.html
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| tumorigenesis |
the growth and development of a tumor, or accumulation of rapidly proliferating cells.
출처: www.sfaf.org/treatment/beta/b34/b34glos.html
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