| procollagen-lysine, 2-oxoglutarate 5-dioxygenase | <enzyme> A mixed-function oxygenase that catalyses the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilises molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. Chemical name: Procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating) Registry number: EC 1.14.11.4 (12 Dec 1998) |
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| procollagen-proline dioxygenase | <enzyme> A mixed-function oxygenase that catalyses the hydroxylation of a prolyl-glycyl-containing-peptide, usually in protocollagen, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilises molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. Chemical name: Procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase Registry number: EC 1.14.11.2 (12 Dec 1998) |
| proline, 2-oxoglutarate 3-dioxygenase | <enzyme> Prolyl 3-hydroxylase is separate enzyme from prolyl 4-hydroxylase; catalyses post translational modification of collagen Registry number: EC 1.14.11.7 Synonym: proline 3-hydroxylase, prolyl 3-hydroxylase (26 Jun 1999) |
| protocatechuate 2,3-dioxygenase | <enzyme> From bacillus macerans; catalyses the conversion of protocatechuate to alpha-hydroxy-delta-carboxymuconic saemialdehyde in the presence of oxygen Registry number: EC 1.13.11.- (26 Jun 1999) |
| protocatechuate-3,4-dioxygenase | <enzyme> An enzyme that catalyses the oxidation of protocatechuate to 3-carboxy-cis-cis-muconate in the presence of molecular oxygen. It contains ferric ion. Chemical name: Protocatechuate:oxygen 3,4-oxidoreductase (decyclizing) Registry number: EC 1.13.11.3 (12 Dec 1998) |
| homogentisate 1,2-dioxygenase | An iron-containing enzyme that catalyses the oxidative cleavage of the benzene ring in homogentisic acid by O2, forming 4-maleylacetoacetate; an absence or deficiency of this enzyme will result in alcaptonuria. Synonym: homogentisic acid oxidase. (05 Mar 2000) |
| hydroxyquinol 1,2-dioxygenase | <enzyme> Catalyses oxidative ring fission of hydroxyquinol to yield 3-hydroxy-cis,cis-muconate; contains ferric iron; specific for hydroxyquinol Registry number: EC 1.13.11.- Synonym: 1,2,4-trihydroxybenzene 1,2-dioxygenase (26 Jun 1999) |
| hyoscyamine (6S)-dioxygenase | <enzyme> A 2-oxoglutarate-dependent dioxygenase that catalyses hydroxylation of l-hyoscyamine to 6beta-hydroxyhyoscyamine in biosynthetic pathway to scopolamine; requires fe2+ Registry number: EC 1.14.11.11 Synonym: hyoscyamine 6beta-hydroxylase, hyoscyamine 6 beta-hydroxylase (26 Jun 1999) |
| naphthalene dioxygenase | <enzyme> Forms cis-(1r,2s)-dihydroxy-1,2-dihydronaphthalene; requires NADH Registry number: EC 1.14.12.- (26 Jun 1999) |
| dioxin dioxygenase | <enzyme> Catalyses initial step of the degradations of dibenzofuan and dibenzo-p-dioxin; isolated from sphingomonas Registry number: EC 1.14.99.- (26 Jun 1999) |
| dioxygenase | An oxidoreductase that incorporates two atoms of oxygen (from one molecule of O2) into the (reduced) substrate. (05 Mar 2000) |
| DOPA dioxygenase | <enzyme> Key enzyme in betalain biosynthesis pathway of amanita muscaria; genbank y12886 Registry number: EC 1.14.99.- Synonym: dopa-4,5-dioxygenase, doda gene product (26 Jun 1999) |
| isopropylbenzene dioxygenase | <enzyme> Pseudomonas putida enzyme; forms 2,3-dihydro-2,3-dihydroxyisopropylbenzene Registry number: EC 1.13.11.- Synonym: isopropylbenzene 2,3-dioxygenase, cumene 2,3-dioxygenase (26 Jun 1999) |
| ortho-halobenzoate 1,2-dioxygenase | <enzyme> A three-component broad substrate-specific enzyme that requires oxygen, NADH, fe(ii) and flavin adenine dinucleotide; degrades 2,4-, 2,5-dichloro-, 2-chloro (& a variety of other substituted halobenzoates) to 4-chlorocatechol and catechol Registry number: EC 1.14.12.- (26 Jun 1999) |
| terephthalate 1,2-dioxygenase | <enzyme> Converts terephthalate to (1r,2s)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylic acid and protocatechuate; has 2 components, r (reductase) and z (oxygenase); from comamonas testosteroni; partial amino acid sequence given in first source Registry number: EC 1.- Synonym: ter-1,2-dioxygenase (26 Jun 1999) |