| tropical myositis | A disease observed in Samoa and in tropical Africa, marked by pains in the extremities, fever of a remittent or intermittent type, and abscesses in the muscles in various parts of the body (may result in death from sepsis); causative organisms are Staphylococcus aureus and Streptococcus pyogenes, but usually the disease is associated with parasitic infections. Synonym: bungpagga, lambo lambo, tropical myositis, tropical pyomyositis. (05 Mar 2000) |
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| tropical pyomyositis | A disease observed in Samoa and in tropical Africa, marked by pains in the extremities, fever of a remittent or intermittent type, and abscesses in the muscles in various parts of the body (may result in death from sepsis); causative organisms are Staphylococcus aureus and Streptococcus pyogenes, but usually the disease is associated with parasitic infections. Synonym: bungpagga, lambo lambo, tropical myositis, tropical pyomyositis. (05 Mar 2000) |
| tropical sore | Infection with promastigotes (leptomonads) of Leishmania tropica and of leishmaniasis major inoculated into the skin by the bite of an infected sandfly, Phlebotomus (commonly P. Papatasi); it is endemic in parts of Asia Minor, northern Africa, and India, and is known by innumerable names, each indicating its locality (e.g., Aleppo, Baghdad, Delhi, or Jericho boil; Aden ulcer; Biskra button); the ulcer begins as a papule that enlarges to a nodule and then breaks down into an ulcer. Two distinctive clinical and epidemiological diseases are recognised, the more common and widespread zoonotic rural disease with a moist acute form, caused by L. Major, with reservoir rodent hosts; and an urban, anthroponotic, dry, chronic form of leishmaniasis caused by leishmaniasis tropica, without a reservoir host, and now largely controlled. See: zoonotic cutaneous leishmaniasis, anthroponotic cutaneous leishmaniasis. Synonym: juccuya, Old World leishmaniasis, tropical sore. (05 Mar 2000) |
| tropical splenomegaly | A chronic disease, occurring in India, Assam, China, the area formerly known as the Mediterranean littoral areas, the Middle East, India, Pakistan, China, South and Central America, Asia, Africa caused by Leishmania donovani and transmitted by the bite of an appropriate species of sandfly of the genus Phlebotomus or Lutzomyia; the organisms grow and multiply in macrophages, eventually causing them to burst and liberate amastigote parasites which then invade other macrophages; proliferation of macrophages in the bone marrow causes crowding out of erythroid and myeloid elements, resulting in leukopenia, and anaemia, splenomegaly, and hepatomegaly which are characteristic, along with enlargement of lymph nodes; fever, fatigue, malaise, and secondary infections also occur; different strains of leishmaniasis donovani occur; leishmaniasis infantum in Eurasia, leishmaniasis chagasi in Latin America. Synonym: Assam fever, black sickness, Burdwan fever, cachectic fever, Dumdum fever, kala azar, tropical splenomegaly. (05 Mar 2000) |
| tropical splenomegaly syndrome | A syndrome characterised by persistent splenomegaly, exceptionally high serum IgM and malaria antibody levels, and hepatic sinusoidal lymphocytosis; believed to be a disturbance in the T-lymphocyte control of the humoral response to recurrent malaria. Synonym: tropical splenomegaly syndrome. (05 Mar 2000) |
| tropical typhus | See Typhus, scrub. (12 Dec 1998) |
| tropical ulcer | The lesion occurring in cutaneous leishmaniasis, tropical phagedenic ulceration caused by a variety of microorganisms, including mycobacteria; common in northern Nigeria. Synonym: tropical sore. (05 Mar 2000) |
| colitis, spastic | See Colitis, mucus. (12 Dec 1998) |
| pseuodoparalysis, spastic | Better known as creutzfeldt-jakob disease. A dementing disease of the brain. It is believed due to an unconventional (not a bacteria or virus), transmissible agent called a prion. Symptoms of cjd include forgetfulness, nervousness, jerky trembling hand movements, unsteady gait, muscle spasms, chronic dementia, balance disorder, and loss of facial expression. Cjd is classified as a spongiform encephalopathy. most cases occur randomly (sporadically), but inherited forms exist. There is neither treatment nor cure for cjd. Other names for cjd include creutzfeldt-jakob syndrome and jakob-creutzfeldt disease. (12 Dec 1998) |
| spastic | 1. Of the nature of or characterised by spasms. 2. Hypertonic, so that the muscles are stiff and the movements awkward. 3. A person exhibiting spasticity, such as occurs in spastic paralysis or in cerebral palsy. Origin: Gr. Spastikos (13 Nov 1997) |
| spastic abasia | Abasia due to a spastic contraction of the muscles when an attempt is made to walk. (05 Mar 2000) |
| spastic anaemia | Local anaemia resulting from nontransitory contraction of the arterial vessels in the affected region. (05 Mar 2000) |
| spastic colitis | See Syndrome, irritable bowel. (12 Dec 1998) |
| spastic colon | A bowel disorder with no demonstrable organic abnormality. Often referred to as a functional bowel disorder or spastic colon. Symptoms include episodic, crampy abdominal pains often related to anxiety. (27 Sep 1997) |
| spastic diplegia | A type of cerebral palsy in which there is bilateral spasticity, with the lower extremities more severely affected. Compare: flaccid paralysis. Synonym: Erb-Charcot disease, infantile diplegia, Little's disease, spastic spinal paralysis, tabes spasmodica. (05 Mar 2000) |