| LETD | lowest effective toxic dose |
|---|---|
| MTC | mass transfer coefficient; maximum tolerated concentration; maximum toxic concentration; medical tes... |
| ODTS | organic dust toxic syndrome |
| Q-TWIST | quality-adjusted time without symptoms of disease and subjective toxic effects of treatment |
| RTECS | Registry of Toxic Effects of Chemical Substances |
| toxic shock syndrome | <syndrome> A blood-borne bacterial infection caused by the genus Staphylococcus. Usually effects menstruating females under the age of thirty and was associated in the past with the use of a particular type of tampon (no longer used). Common symptoms include: fever, chills, vomiting, sore throat, headache and decreased urine output. Progression of disease can result in lowering of blood pressure (shock) and renal failure. Treatment includes hospitalisation and intravenous antibiotics emergently. (27 Sep 1997) |
|---|---|
| toxic tetanus | Tonic spasms caused by strychnine or other tetanic. Synonym: toxic tetanus. (05 Mar 2000) |
| toxic unit | A unit formerly synonymous with minimal lethal dose but which, because of the instability of toxins, is now measured in terms of the quantity of standard antitoxin with which the toxin combines. See: L doses, minimal lethal dose. Synonym: toxin unit. (05 Mar 2000) |
| epidermal necrolysis, toxic | An exfoliative disease of skin seen primarily in adults and characterised by flaccid bullae and spreading erythema so that the skin has the appearance of being scalded. It results primarily from a toxic reaction to various drugs, but occasionally occurs as a result of infection, neoplastic conditions, or other exposure. (12 Dec 1998) |
| alpha substance | A filamentous plasmatic material, beaded with granules, demonstrable by means of vital staining in the immature red blood cells. Synonym: alpha substance, filar mass, filar substance, substantia reticularis, substantia reticulofilamentosa. Synonym: reticular formation. (05 Mar 2000) |
| anterior perforated substance | A region at the base of the brain through which numerous small branches of the anterior and middle cerebral arteries (lenticulostriate arteries) enter the depth of the cerebral hemisphere; it is bordered medially by the optic chasm and anterior half of the optic tract, rostrally and laterally by the lateral olfactory stria; its anteromedial part corresponds to the olfactory tubercle. Synonym: substantia perforata anterior, locus perforatus anticus, olfactory area. (05 Mar 2000) |
| autacoid substance | A substance formed metabolically by one set of cells, which alters the function of other cells. (This term is sometimes used in place of the term hormone.) (05 Mar 2000) |
| bacteriotropic substance | Opsonin or other substance that alters bacterial cells in such a manner that they are more susceptible to phagocytic action. (05 Mar 2000) |
| basophilic substance | The material consisting of granular endoplasmic reticulum and ribosomes that occurs in nerve cell bodies and dendrites. Synonym: basophil substance, basophilic substance, chromophil substance, Nissl bodies, Nissl granules, substantia basophilia, tigroid bodies, tigroid substance. (05 Mar 2000) |
| basophil substance | The material consisting of granular endoplasmic reticulum and ribosomes that occurs in nerve cell bodies and dendrites. Synonym: basophil substance, basophilic substance, chromophil substance, Nissl bodies, Nissl granules, substantia basophilia, tigroid bodies, tigroid substance. (05 Mar 2000) |
| blood group substance | Blood group-specific substances A and B, solution of complexes of polysaccharides and amino acids that reduces the titre of anti-A and anti-B isoagglutinins in serum from group O persons; used to render group O blood reasonably safe for transfusion into persons of group A, B, or AB, but does not affect any incompatibility that results from various other factors, such as Rh. (05 Mar 2000) |
| vasodepressor substance | An incompletely characterised chemical, apparently produced during liver damage, that tends to decrease vascular pressures and relax arterial walls. (05 Mar 2000) |
| gelatinous substance | The apical part of the posterior horn (dorsal horn; posterior gray column) of the spinal cord's gray matter, composed largely of very small nerve cells; its gelatinous appearance is due to its very low content of myelinated nerve fibres. Synonym: substantia gelatinosa, Rolando's gelatinous substance, Rolando's substance. (05 Mar 2000) |
| glandular substance of prostate | The glandular tissue of the prostate as distinct from the stroma and capsule. Synonym: substantia glandularis prostatae. (05 Mar 2000) |
| Reichstein's substance | One of several steroids; e.g., Reichstein's substance F (cortisone), Reichstein's substance H (corticosterone), Reichstein's substance M (cortisol), Reichstein's substance Q (cortexone), and Reichstein's substance S (cortexolone). Synonym: Reichstein's compound. (05 Mar 2000) |