| toxic shock syndrome | <syndrome> A blood-borne bacterial infection caused by the genus Staphylococcus. Usually effects menstruating females under the age of thirty and was associated in the past with the use of a particular type of tampon (no longer used). Common symptoms include: fever, chills, vomiting, sore throat, headache and decreased urine output. Progression of disease can result in lowering of blood pressure (shock) and renal failure. Treatment includes hospitalisation and intravenous antibiotics emergently. (27 Sep 1997) |
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| toxic substances | A chemical or mixture of chemicals that presents a high risk of injury to human health or to the environment. (05 Dec 1998) |
| toxic tetanus | Tonic spasms caused by strychnine or other tetanic. Synonym: toxic tetanus. (05 Mar 2000) |
| toxic unit | A unit formerly synonymous with minimal lethal dose but which, because of the instability of toxins, is now measured in terms of the quantity of standard antitoxin with which the toxin combines. See: L doses, minimal lethal dose. Synonym: toxin unit. (05 Mar 2000) |
| epidermal necrolysis, toxic | An exfoliative disease of skin seen primarily in adults and characterised by flaccid bullae and spreading erythema so that the skin has the appearance of being scalded. It results primarily from a toxic reaction to various drugs, but occasionally occurs as a result of infection, neoplastic conditions, or other exposure. (12 Dec 1998) |
| acidophil adenoma | <endocrinology, oncology, tumour> A benign tumour, usually found in the anterior lobe of the pituitary gland, whose cells stain with acid dyes. Such pituitary tumours may give rise to excessive secretion of growth hormone, resulting in gigantism or acromegaly. A specific type of acidophil adenoma may give rise to nonpuerperal galactorrhoea. (25 Jun 1999) |
| ACTH-producing adenoma | <tumour> A pituitary tumour composed of corticotrophs that produce ACTH, often a basophilic adenoma; may give rise to Cushing's disease or Nelson's syndrome. (05 Mar 2000) |
| adenoma | <oncology, tumour> A benign epithelial tumour in which the cells form recognisable glandular structures or in which the cells are clearly derived from glandular epithelium. (18 Nov 1997) |
| adenoma, adrenal cortical | A benign neoplasm of adrenal cortical cells resembling normal adrenal cells histologically but possessing functional autonomy. In general it does not exceed 5 cm in its largest dimension, although benign tumours exceeding 20 cm have been reported. Adrenal cortical adenomas produce hypercortisolism and hyperaldosteronism, but seldom produce adrenogenital syndromes. For the most part the prognosis after surgery is reasonably favourable. (12 Dec 1998) |
| adenoma, basophil | A small tumour of the anterior lobe of the pituitary gland whose cells stain with basic dyes. It may give rise to excessive secretion of acth, resulting in cushing's syndrome. (12 Dec 1998) |
| adenoma, bile duct | A benign tumour of the intrahepatic bile ducts. (12 Dec 1998) |
| adenoma, chromophobe | A tumour of the anterior lobe of the pituitary gland whose cells do not stain readily with either acid or basic dyes and whose presence may be associated with hypopituitarism. Although classically these adenomas have been said to be composed of sparsely granulated or degranulated (nonfunctioning) cells, some contain functioning cells and may be associated with a hyperpituitary state, e.g., acromegaly or cushing's syndrome. (12 Dec 1998) |
| adenoma fibrosum | <oncology, tumour> A benign solid growth, usually found in the breast. (09 Oct 1997) |
| adenoma, islet cell | A benign tumour of the islets of langerhans that may occur anywhere throughout the pancreas. Such tumours may result in hyperinsulinism or zollinger-ellison syndrome. (12 Dec 1998) |
| adenoma, liver cell | A benign epithelial tumour of the liver. (12 Dec 1998) |