| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| 영문 | Electric convulsive therapy(ECT) | 한글 | 전기경련요법 |
|---|---|---|---|
| 설명 | 뇌에 전기 자극을 주어 인위적으로 경련을 유발함으로써 정신 병을 치료하는 방법. 전기쇼크요법(electroshock therapy)이라고도 한다. 1938년에 이탈리아의 체를레티와 비니에 의해 시작되었다. 작용기전은 확실치 않으나 뇌의 신진대사, 생화학 및 효소 등에 변화를 일으킨다는 생물학적, 생화학적 학설이 유력하다. 적응증으로 가장 효과적인 병은 우울증으로 특히 여성에서 갱년기에 호발하는 갱년기 우울증, 우울증과 조증(아주 기분이 좋은 상태가 지속되는 정신병)이 일정한 주기를 두고 반복하는 조울증에 잘 쓰이며, 80~90%에서 효과가 있다. |
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| RT | radiologic technologist; radiotelemetry; radiotherapy; radium therapy; rapid tranquilization; reacti... |
|---|---|
| PT | pain threshold; parathormone; parathyroid; paroxysmal tachycardia; part time; patient; pericardial t... |
| TT | tablet triturate; tactile tension; tendon transfer; test tube; testicular torsion; tetanus toxin; te... |
| TB | Taussig-Bind [syndrome]; terabyte; term birth; terminal bronchiole; terminal bronchus; thromboxane B... |
| TCA | T-cell A locus; terminal cancer; tetracyclic antidepressant; total cholic acid; total circulating al... |
| total fertility rate | <epidemiology> The number of children an average women would have assuming that she lives her full reproductive lifetime. (05 Dec 1998) |
|---|---|
| total haematuria | Uniform mixing of blood in the entire voided urine, commonly indicating an upper or mid-urinary tract source of bleeding. (05 Mar 2000) |
| total hyperopia | That which can be determined after complete paralysis of accommodation by means of a cycloplegic. (05 Mar 2000) |
| total hysterectomy | Complete surgical removal of the uterus and cervix. Also called a complete hysterectomy. (12 Dec 1998) |
| total iron binding capacity | <biochemistry, haematology> A test that measures indirectly the transferrin level in the bloodstream. Transferrin is a protein that carries iron in the body. Normal values are 240 to 450 mcg/dl. This test is used to evaluate anaemia. Greater than normal total iron binding capacity can be seen in: iron deficiency anaemia, late pregnancy and polycythaemia vera. Lower than normal total iron binding capacity can be seen in cirrhosis, sickle cell anaemia, hypoproteinaemia, pernicious anaemia and haemolytic anaemia. The use of birth control pills can lead to increased total iron binding capacity measurements. Acronym: TIBC (12 Jan 1998) |
| total joint arthroplasty | Arthroplasty in which both joint surfaces are replaced with artificial materials, usually metal and high-density plastic. (05 Mar 2000) |
| total keratoplasty | Corneal transplant in which the entire cornea is removed and replaced. (05 Mar 2000) |
| total knee joint replacement | Surgery involving the replacement of the knee joint with artificial components which reestablishes normal joint function. Indicated in cases of severe knee fracture or degenerative arthritis (DJD) unresponsive to medical therapy. (27 Sep 1997) |
| total lung capacity | The volume of air contained in the lungs at the end of a maximal inspiration. It is the equivalent to each of the following sums: vital capacity plus residual volume; inspiratory capacity plus functional residual capacity; tidal volume plus inspiratory reserve volume plus functional residual capacity; tidal volume plus inspiratory reserve volume plus expiratory reserve volume plus residual volume. (12 Dec 1998) |
| total mastectomy | Excision of the breast including the nipple, areola, and most of the overlying skin. Synonym: total mastectomy. (05 Mar 2000) |
| total necrosis | Complete necrosis of the cytologic and histologic elements in a portion of tissue, as in caseous necrosis, death of an entire organ or part. (05 Mar 2000) |
| total or partial anomalous pulmonary venous connections | Connections in which some or all of the pulmonary veins connect to the right atrium or one of its tributaries. (05 Mar 2000) |
| total parenteral nutrition | <pharmacology> Intravenous feeding that provides patients with all essential nutrients when they are unable to feed themselves. Acronym: TPN (12 Jan 1998) |
| total pelvic exenteration | Removal of the urinary bladder, lower parts of the ureter, vagina, uterus, adnexa, rectum, anus, and adjacent lymph nodes; a colostomy and urinary diversion are necessary. Synonym: Brunschwig's operation. (05 Mar 2000) |
| total peripheral resistance | The total resistance to flow of blood in the systemic circuit; the quotient produced by dividing the mean arterial pressure by the cardiac minute-volume. Synonym: peripheral resistance. (05 Mar 2000) |