| retinoic acid 4-hydroxylase | <enzyme> Catalyses the hydroxylation of all-trans retinoic acid to 4-hydroxyretinoic acid Registry number: EC 1.14.- Synonym: ra-4-hydroxylase, cytochrome p450 4-hydroxylase, cyp450 4-hydroxylase (26 Jun 1999) |
|---|---|
| retinol 4-hydroxylase | <enzyme> Converts retinol to 4-hydroxyretinol in presence of NADPH Registry number: EC 1.14.13.- (26 Jun 1999) |
| chlorsulfuron-5-hydroxylase | <enzyme> Hydroxylates the herbicide chlorsulfuron; 5-hydroxychlorsulfuron is not observed intact in plants but is transformed immediately to a glucose conjugate Registry number: EC 1.14.99.- (26 Jun 1999) |
| cholesterol 26-hydroxylase | <enzyme> Cyt p-450 dependent, ferredoxin involved Registry number: EC 1.14.15.- (26 Jun 1999) |
| mevastatin hydroxylase | <enzyme> Hydroxylates ml-236b (mevastatin) to pravastatin; requires NADH-cytochrome p-450 reductase Registry number: EC 1.14.13.- Synonym: cytochrome p-450sca monoxygenase, cytochrome p-450(sca) (26 Jun 1999) |
| phenylalanine 4-hydroxylase | <enzyme> An enzyme that catalyses the oxidation of l-phenylalanine to l-tyrosine with O2 and tetrahydrobiopterin (the latter forming the dihydro derivative) which is reduced by NADPH and a reductase to the active form; a deficiency of either of these enzymes will result in phenylketonuria. Synonym: phenylalanine 4-hydroxylase. (05 Mar 2000) |
| phenylalanine hydroxylase | <enzyme> An enzyme of the oxidoreductase class that catalyses the reaction l-phenylalanine, tetrahydrobiopterin, and oxygen to yield l-tyrosine, dihydrobiopterin, and water, the reaction synthesizing tyrosine from phenylalanine. Chemical name: L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating) Registry number: EC 1.14.16.1 (12 Dec 1998) |
| phenylalanine hydroxylase phosphatase | <enzyme> Catalyses dephosphorylation of phosphorylated phenylalanine hydroxylase Registry number: EC 3.1.3.- Synonym: phe hydroxylase phosphatase (26 Jun 1999) |
| phytanoyl-coenzyme A hydroxylase | <enzyme> Mutations in gene pahx result in refsum disease; amino acid sequence given in second source; genbank af023462-3 Registry number: EC 1.14.- Synonym: phytanoyl-CoA hydroxylase, pahx protein, pahx gene product (26 Jun 1999) |
| warfarin-7-hydroxylase | <enzyme> Hydroxylates warfarin in presence of cytochrome p-450 and NADPH Registry number: EC 1.14.13.- (26 Jun 1999) |
| corticosterone 15alpha-hydroxylase | <enzyme> Use of cytochrome p-450coh in which phe209 is replaced by asn gives the cytochrome p-450coh a high corticosterone 15alpha hydroxylase activity instead of a coumarin hydroxylase activity Registry number: EC 1.14.99.- Synonym: co 15-hydroxylase (26 Jun 1999) |
| coumarin hydroxylase | <enzyme> Different preparations hydroxylate at position 3 and position 7; if cytochrome p-450coh is mutated at position 209, its substrate specificity is changed from coumarin hydroxylation to steroid hydroxylation Registry number: EC 1.14.99.- Synonym: cytochrome p-450coh, cytochrome p-4502a-5, cyp2a-5 gene product, coumarin 7-hydroxylase, cytochrome p-450 2a6, cyp2a6, cytochrome p-450 2a3, cyp2a3, p450 2a5, dhea hydroxylase, cyp2a5 (26 Jun 1999) |
| cymA hydroxylase reductase | <enzyme> Flavoprotein electron transport reductase from pseudomonas aureofaciens; genbank u86603 Registry number: EC 1.- Synonym: p-cymene methyl hydroxylase reductase, cyma gene product (26 Jun 1999) |
| cytochrome P-450-dependent digitoxin 12beta-hydroxylase | <enzyme> Isolated from digitalis lantata cell cultures Registry number: EC 1.14.99.- Synonym: digitoxin 12beta-hydroxylase (26 Jun 1999) |
| salicylic acid 5-hydroxylase | <enzyme> Catalyses conversion of salicylic acid to gentisic acid Registry number: EC 1.14.- Synonym: salicylate 5-hydroxylase (26 Jun 1999) |