| spastic paraplegia | Paresis of the lower extremities with increased muscle tone and spasmodic contraction of the muscles. Synonym: Erb-Charcot disease. (05 Mar 2000) |
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| spastic paraplegia, hereditary | An insidiously progressive inherited disorder (probably autosomal dominant) characterised by distal limb weakness. Stiffness of the legs in walking due to the spasticity marks the onset of the disorder. Peripheral sensory neurons may be affected in the later stages of the disease. (12 Dec 1998) |
| spastic pseuodoparalysis | Better known as creutzfeldt-jakob disease (cjd). A dementing disease of the brain. It is believed due to an unconventional (not a bacteria or virus), transmissible agent called a prion. Symptoms of cjd include forgetfulness, nervousness, jerky trembling hand movements, unsteady gait, muscle spasms, chronic dementia, balance disorder, and loss of facial expression. Cjd is classified as a spongiform encephalopathy. most cases occur randomly (sporadically), but inherited forms exist. There is neither treatment nor cure for cjd. Other names for cjd include creutzfeldt-jakob syndrome and jakob-creutzfeldt disease. (12 Dec 1998) |
| spastic speech | Labored speech related to increased tone of muscles. (05 Mar 2000) |
| spastic spinal paralysis | A type of cerebral palsy in which there is bilateral spasticity, with the lower extremities more severely affected. Compare: flaccid paralysis. Synonym: Erb-Charcot disease, infantile diplegia, Little's disease, spastic spinal paralysis, tabes spasmodica. (05 Mar 2000) |
| spastic syndrome in cattle | A disease of the nervous system manifested by spastic contractions of the muscles of one or both hind legs, most common in old bulls; the cramps usually become more frequent and severe, eventually resulting in decreasing the usefulness of the animal. (05 Mar 2000) |
| infantile spastic paraplegia | A spastic paralysis of the lower extremities occurring in the infant. Synonym: infantile spastic paraplegia. (05 Mar 2000) |