| single ascertainment | Method of ascertainment of locating affected individuals by hospital or clinic admission or another way in which probability of encountering the same family twice approaches zero; thus, the probability that a family will be ascertained is proportional to the number of affected members. (05 Mar 2000) |
|---|---|
| single-blind method | A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned. (12 Dec 1998) |
| single bond | A covalent bond resulting from the sharing of one pair of electrons; e.g., H3C-CH3 (ethane). (05 Mar 2000) |
| single cell protein | <protein> Protein produced by single cells in culture, especially Candida species, that could be of possible commercial importance in providing food sources from biotechnological processes. (10 Oct 1997) |
| single channel recording | Variant of patch clamp technique. (18 Nov 1997) |
| single-foot | An irregular gait of a horse; called also single-footed pace. See Single, "Single-foot is an irregular pace, rather rare, distinguished by the posterior extremities moving in the order of a fast walk, and the anterior extremities in that of a slow trot." (Stillman (The Horse in Motion)) Source: Websters Dictionary (01 Mar 1998) |
| single-gene diseases | Hereditary disorders caused by a change (mutation) in a single gene. There are thousands of single-gene diseases including achondroplastic dwarfism, huntington disease, cystic fibrosis, sickle cell disease, duchenne muscular dystrophy, and haemophilia. Single-gene diseases typically describe classic simple mendelian patterns of inheritance (as autosomal dominant, autosomal recessive, and x-linked traits) by comparison with polygenic diseases. (12 Dec 1998) |
| single gene disorder | Hereditary disorder caused by a mutant allele of a single gene (for example, Duchenne muscular dystrophy, retinoblastoma, sickle cell disease). Compare: polygenic disorders. (09 Oct 1997) |
| single-hearted | Having an honest heart; free from duplicity. Sin"gle-heart"edly. Source: Websters Dictionary (01 Mar 1998) |
| single immunodiffusion | See: gel diffusion precipitin tests in one dimension, gel diffusion precipitin tests in two dimensions. (05 Mar 2000) |
| single lucent skull lesion | <radiology> Mnemonic: HELP ME, haemangioma, epidermoid / dermoid, leptomeningeal cyst, lambdoid suture defect, Paget's (osteoporosis circumscripta), post-surgical, metastasis (solitary), eosinophilic granuloma, encephalocele (12 Dec 1998) |
| single-minded | Having a single purpose; hence, artless; guileless; single-hearted. Source: Websters Dictionary (01 Mar 1998) |
| single parent | An unmarried natural, adoptive, or substitute parent of a dependent child, whether living with or visiting the child. To be used also for single-parent families. The concept includes the never-married, as well as the divorced and widowed. (12 Dec 1998) |
| single-payer system | An approach to health care financing with only one source of money for paying health care providers. The scope may be national (the canadian system), state-wide, or community-based. The payer may be a governmental unit or other entity such as an insurance company. The proposed advantages include administrative simplicity for patients and providers, and resulting significant savings in overhead costs. (12 Dec 1998) |
| single person | The unmarried man or woman. (12 Dec 1998) |