| AMP-activated protein kinase kinase | <enzyme> An endogenous kinase kinase; reactivates the inactive form of AMP-activated protein kinase (AMP-pk); phosphorylates the 63-kD subunit of AMP-pk Registry number: EC 2.7.1.- Synonym: AMP-pk reactivator, hmg CoA reductase kinase kinase (26 Jun 1999) |
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| calmodulin-dependent protein kinase IV kinase | <enzyme> Phosphorylates and activates cam-kinase iv; from brain Registry number: EC 2.7.10.- Synonym: cam-kinase iv kinase (26 Jun 1999) |
| MAPKAP kinase-2 reactivating kinase | <enzyme> A mapk-like enzyme; homologous to p42(mapk) and p44(mapk); activated by phosphorylation of serine/threonine and tyrosine residues Registry number: EC 2.7.1.- Synonym: mapkap kinase-2 rk (26 Jun 1999) |
| ribosomal protein S6 kinase kinase | <enzyme> Isolated from unfertilised xenopus eggs; a 41 kD enzyme that is associated, in vivo, with phosphorylation on threonine and tyrosine residues and, in vitro, with phosphorylation on serine as well Registry number: EC 2.7.1.- Synonym: rsk kinase (26 Jun 1999) |
| protein kinase B kinase | <enzyme> Phosphorylates and activates protein kinase b on threonine-308; requires phosphatidylinositol-3,4,5-trisphosphate Registry number: EC 2.7.10.- Synonym: upstream kinase, pkb kinase (26 Jun 1999) |
| acne simplex | <dermatology> A form of acne which results from the bacterial infection of cysts deep within the skin. Generally requires treatment with antibiotics and other agents (Isotretinoin). Without treatment cystic acne may result in scarring. (27 Sep 1997) |
| adiposis tuberosa simplex | A condition resembling adiposis dolorosa, in which the fat occurs in small, nodular masses, which are sensitive to touch and may be spontaneously painful, on the abdomen or on the extremities. (05 Mar 2000) |
| articulatio simplex | One composed of two bones only. Synonym: articulatio simplex. (05 Mar 2000) |
| carcinoma simplex | An obsolete term for any form of carcinoma in which the relative proportions of stroma and neoplastic epithelial cells are not unusual, i.e., stromal elements are not comparatively abundant, nor are they reduced in amount or lacking; an obsolete term for a carcinoma lacking any identifiable microscopic pattern, such as glandular structure. (05 Mar 2000) |
| verruca simplex | A keratotic papilloma of the epidermis which occurs most frequently in young persons as a result of localised infection by human papilloma virus, usually types 2 and 4; the lesions are of variable duration, eventually undergoing spontaneous regression, and are both exophytic and endophytic, with hyperkeratosis, parakeratosis, hypergranulosis, koilocytosis, and papillomatosis. Synonym: common wart, infectious warts, verruca simplex, viral wart. (05 Mar 2000) |
| periodontitis simplex | Horizontal resorption of the alveolar process with pockets of even depth on adjacent teeth; traumatic occlusion is not a factor. (05 Mar 2000) |
| pneumothorax simplex | Pneumothorax, without known cause, in an otherwise healthy person. (05 Mar 2000) |
| crus membranaceum simplex ductus saemicircularis | The non-ampullary end of the lateral saemicircular duct that opens independently into the utricle. Synonym: crus membranaceum simplex ductus saemicircularis, simple membranous limb of saemicircular duct. (05 Mar 2000) |
| scarlatina simplex | A mild form of the disease. (05 Mar 2000) |
| herpes simplex | <virology> The Herpes simplex virus is responsible for several different infections in humans: gingivostomatitis (in children), pharyngitis, oral and lip lesions (recurrent Herpes simplex type 1), proctitis, (type 2) and genital herpes (type 2). (27 Sep 1997) |