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osteoporotic marrow defect Focal osteoporotic bone marrow defect of the jaw; a focal radiolucent defect composed of normal marrow.
(05 Mar 2000)
Eisenmenger's defect The combination of ventricular septal defect with pulmonary hypertension and consequent right-to-left shunt through the defect, with or without an associated overriding aorta.
Synonym: Eisenmenger's defect, Eisenmenger's disease, Eisenmenger's tetralogy.
(05 Mar 2000)
endocardial cushion defect <radiology> Persistence of primitive atrioventricular canal and anomalies of AV valves associated with: Down syndrome: in 25% of Trisomy 21 an ECD is present; in 45% of ECD Trisomy 21 is present, asplenia/polysplenia types: complete (AV canal), partial findings: gooseneck deformity on angiogram, increased pulmonary vascularity, enlarged pulmonary artery, enlarged RV, LV, RA; normal LA (secondary to atrial septal defect)
(12 Dec 1998)
enzyme defect A disorder resulting from a deficiency (or functional abnormality) of an enzyme. In 1902 Archibald Garrod first attributed a disease to an enzyme defect: an inborn error of metabolism. Today, newborns are routinely screened for certain enzyme defects such as PKU (phenylketonuria) and galactosaemia, an error in the handling (metabolism) of the sugar galactose.
(12 Dec 1998)
fibrous cortical defect A common 1 to 3 cm defect in the cortex of a bone, most commonly the lower femoral shaft of a child, filled with fibrous tissue. Nonosteogenic or nonossifying fibroma by convention refers to lesions greater than 3 cm in diameter.
See: nonossifying fibroma.
Synonym: nonosteogenic fibroma.
(05 Mar 2000)
uterine filling defect <radiology> Technical, bubble, blood clot, mucoid material, congenital fold, pseudoadhesions / ridging -- folds long axis, neoplasm, submucosal leiomyoma, adenoma, endometrial carcinoma, pregnancy-related, pregnancy, molar pregnancy, retained conceptus, polyp, septated uterus, synechiae, IUD, iatrogenic (post-op)
(12 Dec 1998)
filling defect Displacement of contrast medium by a space-occupying lesion in a radiographic study of a contrast-filled hollow viscus, such as a polyp on a barium enema; also applied to defects in the otherwise uniform distribution of radionuclide in an organ, such as a metastasis in the liver on a 99mTc-sulfur colloid scan.
(05 Mar 2000)
filling defect in renal collecting system <radiology> Common causes: transitional cell carcinoma, blood clot, lucent calculus (urate) less common causes: fungus ball, sloughed papilla, fibroepithelial polyp, invasion by hypernephroma, malakoplakia, vessel impression, metastases
(12 Dec 1998)
lambdoid suture defect <radiology> Well-defined lucent lesion, classically unilateral, associated with neurofibromatosis
(12 Dec 1998)
luteal phase defect Inadequate function of the corpus luteum that may prevent a fertilized egg from implanting in the uterus or may lead to early pregnancy loss.
(09 Oct 1997)
mastectomy, simple Removal of only the breast tissue and nipple and a small portion of the overlying skin.
(12 Dec 1998)
microscope, simple <microscopy> A microscope that has a single converging lens (or a combination of lenses that function optically as a single converging lens). Anton van leeuwenhoek (1632-1723) made good use of the simple microscope to look at the life within a drop of water, and such. The magnifying properties of lenses had been well known in ancient times (for example to the greeks and romans) but it was not until about 1600 that it became possible to make small lenses with the precision needed to make a microscope.
(12 Dec 1998)
simple Undivided, of a leaf, not divided into leaflets, of a hair or an inflorescence, not branched.
(09 Oct 1997)
simple absence A brief clouding of consciousness accompanied by the abrupt onset of 3/sec spikes and waves on EEG.
Synonym: pure absence.
(05 Mar 2000)
simple anchorage Anchorage in which the resistance to the movement of one or more teeth comes solely from resistance to tipping movement of the anchorage unit.
(05 Mar 2000)
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