| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| 영문 | Electric convulsive therapy(ECT) | 한글 | 전기경련요법 |
|---|---|---|---|
| 설명 | 뇌에 전기 자극을 주어 인위적으로 경련을 유발함으로써 정신 병을 치료하는 방법. 전기쇼크요법(electroshock therapy)이라고도 한다. 1938년에 이탈리아의 체를레티와 비니에 의해 시작되었다. 작용기전은 확실치 않으나 뇌의 신진대사, 생화학 및 효소 등에 변화를 일으킨다는 생물학적, 생화학적 학설이 유력하다. 적응증으로 가장 효과적인 병은 우울증으로 특히 여성에서 갱년기에 호발하는 갱년기 우울증, 우울증과 조증(아주 기분이 좋은 상태가 지속되는 정신병)이 일정한 주기를 두고 반복하는 조울증에 잘 쓰이며, 80~90%에서 효과가 있다. |
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| ACT | achievement through counseling and treatment; actin; actinomycin; activated clotting time; advanced ... |
|---|---|
| ERT | esophageal radionuclide transit; estrogen replacement therapy; examination room terminal; external r... |
| ICT | icteric, icterus; indirect Coombs test; inflammation of connective tissue; insulin coma therapy; int... |
| OT | objective test; oblique talus; occlusion time; occupational therapist, occupational therapy; ocular ... |
| PT | pain threshold; parathormone; parathyroid; paroxysmal tachycardia; part time; patient; pericardial t... |
| shock | 1. <psychiatry> A sudden disturbance of mental equilibrium. 2. <cardiology> A condition of profound haemodynamic and metabolic disturbance characterised by failure of the circulatory system to maintain adequate perfusion of vital organs, it may result from inadequate blood volume (hypovolaemic shock), inadequate cardiac function (cardiogenic shock) or inadequate vasomotor tone (neurogenic shock, septic shock). (18 Nov 1997) |
|---|---|
| shock antigen | An antigen capable of producing anaphylactic shock in an animal that has been sensitised to it. (05 Mar 2000) |
| shock, cardiogenic | Shock caused by heart failure. The heart fails to pump blood effectively. For example, a heart attack (a myocardial infarction) can cause an abnormal ineffectual heart beat (an arhythmia) with very slow, rapid, or irregular contractions of the heart, impairing the heart's ability to pump blood, lowering the volume of blood going to vital organs. Cardiogenic shock can also be due to drugs that reduce heart function or an abnormally low level oxygen in the blood (hypoxaemia) caused, for instance, by lung disease. Whatever be the cause, blood vessels constrict and adrenalin-like substances are secreted into the bloodstream, increasing the heart rate. Treatment of cardiogenic shock is aimed at improving the heart's function. Shock after a heat attack is extremely serious. The mortality rate is over 80%. (12 Dec 1998) |
| shock, hypovolaemic | Shock due to a decrease in blood volume. This is the 1 cause of shock. It can be due to loss of blood from bleeding, loss of blood plasma through severe burns, and dehydration. The treatment, first and foremost, is prompt intravenous administration of fluid. (12 Dec 1998) |
| shock index | The quotient of the cardiac rate divided by the systolic blood pressure; normally approximately 0.5, but in shock (e.g., rising pulse rate with falling blood pressure), the index may reach 1.0. (05 Mar 2000) |
| shock lung | In shock, the development of oedema, impaired perfusion, and reduction in alveolar space so that the alveoli collapse. Synonym: pump lung, wet lung, white lung. (05 Mar 2000) |
| shock, psychologic | Trauma due to psychological events, as in shell shock (now known as posttraumatic stress disorder). (12 Dec 1998) |
| shock, septic | Shock due to circulatory insufficiency caused most commonly by gram-negative bacteraemia. It is less often the result of the persistent presence of other micro-organisms in the blood (fungaemia, viraemia); in rare instances, it is caused by gram-positive organisms, but with different symptomatology. (12 Dec 1998) |
| shock, shell | The World War I name for what is known today as posttraumatic stress, this is a psychological disorder that develops in some individuals who have had major traumatic experiences (and, for example, have been in a serious accident or through a war). The person is typically numb at first but later has symptoms including depression, excessive irritability, guilt (for having survived while others died), recurrent nightmares, flashbacks to the traumatic scene, and overreactions to sudden noises. Posttraumatic stress became known as such in the 70s due to the adjustment problems of some vietnam veterans.shots, allergy: known medically as allergy desensitization or allergy immunotherapy, the injections are designed to stimulate the immune system with gradually increasing doses of the substances to which a person is allergic, the aim being to modify or stop the allergy war (by reducing the strength of the IgE and its effect on the mast cells). This form of treatment is very effective for allergies to pollen, mites, cats, and especially stinging insects (e.g., bees, hornets, yellowjackets, wasps, velvet ants, fire ants). Allergy immunotherapy usually takes 6 months to a year to become effective and injections are usually required for 3-5 years. (12 Dec 1998) |
| shock, surgical | Shock that occurs during or after surgical operation. (12 Dec 1998) |
| shock, toxic | See Syndrome, toxic shock. (12 Dec 1998) |
| shock, traumatic | Any shock produced by trauma. (12 Dec 1998) |
| shock treatment | See: electroshock therapy. (05 Mar 2000) |
| shock tube | <radiobiology> A gas-filled tube used in plasma physics to quickly ionize a gas. A capacitor bank charged to a high voltage is discharged into the gas at one tube end to ionize and heat the gas, producing a shock wave that may be studied as it travels down the tube. (09 Oct 1997) |
| shock wave | <radiobiology> Wave produced (for example, in a gas or plasma) as a result of a sudden violent disturbance. To produce a shock wave in a given region, the disturbance must take place in a shorter time than the time required for sound waves to traverse the region. (09 Oct 1997) |