| ADPKD | autosomal dominant polycystic kidney disease |
|---|---|
| ADVIRC | autosomal dominant vitreo-retinochoroidopathy |
| DEBS | dominant epidermolysis bullosa simplex |
| DH | daily habits; day hospital; dehydrocholate; dehydrogenase; delayed hypersensitivity; dermatitis herp... |
| DJOA | dominant juvenile optic atrophy |
mats sex
| X-linked hypogammaglobulinaemia | A congenital, X-linked recessive, primary immunodeficiency characterised by decreased numbers (or absence) of circulating B-lymphocytes with corresponding decrease in immunoglobulins of the five classes; associated with marked susceptibility to infection by pyogenic bacteria (notably, pneumococci and Haemophilus influenzae) beginning after loss of maternal antibodies. X-linked hypogammaglobulinaemia with growth hormone deficiency, hypogammaglobulinaemia combined with a reduced number of B-cells; characterised by short stature, delayed puberty, and recurrent infections. (05 Mar 2000) |
|---|---|
| X-linked ichthyosis | A form of ichthyosis, due to 3-beta-hydroxysteroidsulfate sulfatase deficiency, that appears at birth or in early infancy and affects males; characterised by scaling predominantly on the neck and trunk but not on the palms and soles; histologically, there is hyperkeratosis, a granular layer in the epidermis, and normal epidermal cell turnover. Synonym: steroid sulfatase deficiency. (05 Mar 2000) |
| X-linked locus | Any locus that in normal karyotypes is borne on the X chromosome. (05 Mar 2000) |
| N-acetylated-alpha-linked acidic dipeptidase | <enzyme> Chloride-dependent membrane bound metallopeptidase, most active with the endogenous neuropeptide n-acetyl-l-aspartyl-l-glutamate Registry number: EC 3.4.13.- Synonym: naaladase, glutamate carboxypeptidase II, prostate-specific membrane antigen, psm antigen (26 Jun 1999) |
| ichthyosis, x-linked | Chronic form of ichthyosis that is inherited as a sex-linked recessive trait carried on the x-chromosome and transmitted to the male offspring. It is characterised by severe scaling, especially on the extremities, and is associated with steroid sulfatase deficiency. (12 Dec 1998) |
| enzyme-linked immunoabsorbent assay | <investigation> The enzyme-linked immunoabsorbent assay is serologic test used as a general screening tool for the detection of antibodies to the HIV virus. Reported as positive or negative. Since false positive tests due occur (for example recent flu shot), positives will require further evaluation using the western blot. ELISA technology links an a measurable enzyme to either an antigen or antibody. In this way, it can then measure the presence of an antibody or an antigen in the bloodstream. Acronym: ELISA (27 Sep 1997) |
| enzyme-linked immunosorbent assay | An immunoassay utilizing an antibody labelled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed. (12 Dec 1998) |
| expression-linked copy | <molecular biology> One of many different versions of the variable surface glycoprotein gene of the trypanosome (a parasitic protozoan which causes the disease African sleeping sickness), refers to whichever one of them is currently being expressed on the outer surface of the trypanosome. (09 Oct 1997) |
| y-linked | A gene on the Y chromosome. A y-linked gene is by necessity passed from father to son. (12 Dec 1998) |
| Y-linked gene | A gene located on a Y chromosome. Synonym: holandric gene. (05 Mar 2000) |
| Y-linked locus | Any (haploid) locus that in normal karyotypes is borne on the Y chromosome. The known content is so far small. (05 Mar 2000) |
| flavin-linked dehydrogenase | <enzyme> A dehydrogenase that requires a riboflavin coenzyme to function properly. (09 Oct 1997) |
| linked | Said of two genetic loci that exhibit genetic linkage. (05 Mar 2000) |
| linked gene | <genetics> Genes and / or markers that are so closely associated on the chromosome that they are inherited together in 80% or more of cases. (14 Oct 1997) |
| alternative inheritance | Galton's term for an assumed form in which all the characters are derived from one parent. (05 Mar 2000) |