| lymphoma, large-cell | A form of malignant lymphoma in which the malignant cells resemble histiocytes morphologically but are presently considered to be derived from lymphoid elements. These cells are irregular in shape with relatively abundant, frequently acidophilic cytoplasm. Large-cell lymphoma can occur in both nodular (follicular) and diffuse forms, with the latter being more frequently seen. (12 Dec 1998) |
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| lymphoma, large-cell, diffuse | Malignant lymphoma composed of large cells which may be both cleaved and noncleaved. The pattern is predominantly diffuse. most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation. (12 Dec 1998) |
| lymphoma, large-cell, follicular | Malignant lymphoma in which the majority of neoplastic cells within the follicles are large cleaved or noncleaved cells. The degree to which the follicular centre cells retain their ability to form follicles varies with the state of B-cell transformation. (12 Dec 1998) |
| lymphoma, large-cell, immunoblastic | Malignant lymphoma characterised by the presence of immunoblasts with uniformly round-to-oval nuclei, one or more prominent nucleoli, and abundant cytoplasm. This class may be subdivided into plasmacytoid and clear-cell types based on cytoplasmic characteristics. A third category, pleomorphous, may be analogous to some of the peripheral T-cell lymphomas (lymphoma, T-cell, peripheral) recorded in both the united states and japan. (12 Dec 1998) |
| lymphoma, large-cell, ki-1 | A large-cell, non-hodgkin's, malignant lymphoma with pleomorphic appearance and reactivity with the monoclonal antibody ki-1. The lymphoma is most often found in the skin and lymph nodes and expresses the ki-1 (CD30) antigen (antigens, CD30) on its surface. It is often mistaken for metastatic carcinoma and malignant histiocytosis. (12 Dec 1998) |
| anterior condyloid foramen | The canal through which the hypoglossal nerve emerges from the skull. Synonym: canalis hypoglossalis, anterior condyloid canal of occipital bone, anterior condyloid foramen. (05 Mar 2000) |
| anterior palatine foramen | An opening in the posterolateral corner of the hard palate opposite the last molar tooth, marking the lower end of the pterygopalatine canal. Synonym: foramen palatinum majus, anterior palatine foramen. (05 Mar 2000) |
| aortic foramen | The opening in the diaphragm bounded by the two crura, the vertebral column, and the median arcuate ligament, through which pass the aorta and thoracic duct. Synonym: hiatus aorticus, aortic foramen, aortic opening. (05 Mar 2000) |
| apical dental foramen | The opening at the apex of the root of a tooth that gives passage to the nerve and blood vessels. Synonym: foramen apicis dentis, apical dental foramen, root foramen. (05 Mar 2000) |
| apical foramen of tooth | The opening at the apex of the root of a tooth that gives passage to the nerve and blood vessels. Synonym: foramen apicis dentis, apical dental foramen, root foramen. (05 Mar 2000) |
| arachnoid foramen | The large midline opening in the posterior inferior part of the roof of the fourth ventricle, connecting the ventricle with the cerebellomedullary cistern. Synonym: apertura mediana ventriculi quarti, arachnoid foramen, Magendie's foramen, median aperture of the fourth ventricle. (05 Mar 2000) |
| Bichat's foramen | <anatomy, vein> An expansion of the subarachnoid space extending forward between the corpus callosum and the thalamus; it encloses the internal cerebral veins which caudally join to form the vena magna cerebri (Galen's vein). Synonym: ambient cistern, Bichat's canal, Bichat's foramen, cistern of great vein of cerebrum, cisterna ambiens, cisterna superioris, cisterna venae magnae cerebri, superior cistern. (05 Mar 2000) |
| blind foramen of frontal bone | <anatomy> Blind or caecal foramen of the frontal bone; the blind foramen formed immediately anterior to the crista galli by a notch at the lower end of the frontal crest and its articulation with the ethmoid bone. It is insignificant postnatally, but gives passage to vessels during development. Synonym: foramen caecum ossis frontalis, blind foramen of frontal bone, caecal foramen of frontal bone. (05 Mar 2000) |
| blind foramen of the tongue | <anatomy> A median pit on the dorsum of the posterior part of the tongue, from which the limbs of a V-shaped furrow run forward and outward; it is the site of origin of the thyroid gland and subsequent thyroglossal duct in the embryo. Synonym: foramen caecum linguae, blind foramen of the tongue, caecal foramen of the tongue, Morgagni's foramen, pleuroperitoneal foramen. (05 Mar 2000) |
| Bochdalek's foramen | An opening through the diaphragm, connecting pleural and peritoneal cavities, usually the result of defective development of the pleuroperitoneal membrane in the embryo; if the defect is extensive there may be herniation of digestive organs into the pleural cavity. See: diaphragmatic hernia. Synonym: Bochdalek's foramen. (05 Mar 2000) |