| LRTI | lower respiratory tract illness; lower respiratory tract infection |
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| MRV | minute respiratory volume; mixed respiratory vaccine |
| RI | radiation intensity; radioactive isotope; radioimmunology; recession index; recombinant inbred [stra... |
| RR | radiation reaction; radiation response; rate ratio; rational recovery [group]; recovery room; relati... |
| URD | unspecified respiratory disease; upper respiratory disease |
| tetanus toxin | <protein> Neurotoxin released by Clostridium tetani, becomes active when peptide cleaved proteolytically to heavy (100 kD) and light (50 kD) chains held together by disulphide bond. Heavy chain binds to disialogangliosides (GD2 and GD1b) and part of the peptide (the amino terminal B fragment) forms a pore: light chain is a zinc endopeptidase that specifically attacks synaptobrevin, to block neurotransmitters. See: botulinum toxin (18 Nov 1997) |
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| toxin | <pharmacology> A poison, frequently used to refer specifically to a protein produced by some higher plants, certain animals and pathogenic bacteria, which is highly toxic for other living organisms. Such substances are differentiated from the simple chemical poisons and the vegetable alkaloids by their high molecular weight and antigenicity. Origin: Gr toxikon = arrow poison, from Gr. Toxikos = of or for a bow (18 Nov 1997) |
| toxin spectrum | A figure in the form of a spectrum used by Ehrlich to represent the neutralizing power of antitoxin in the presence of toxin, toxone, etc. (05 Mar 2000) |
| erythrogenic toxin | <protein> Toxin produced by strains of Streptococcus pyogenes responsible for scarlet fever. Three antigenic variants of the toxin are known. It is a small protein that is complexed with hyaluronic acid and can intensify the effects of other toxins such as endotoxin and streptolysin O. (18 Nov 1997) |
| extracellular toxin | <protein> Toxin released from gram-positive and gram-negative bacteria as opposed to endotoxins that form part of the cell wall. Examples are cholera, pertussis and diphtheria toxins. Usually specific and highly toxic. (18 Nov 1997) |
| acute respiratory failure | Loss of pulmonary function either acute or chronic that results in hypoxaemia or hypercarbia. (05 Mar 2000) |
| adult respiratory distress syndrome | <chest medicine, syndrome> A clinical syndrome that includes pulmonary insufficiency. It is a descriptive term that is applied to a variety of diffuse infiltrative processes in the lung. Manifestations include severe shortness of breath, rapid breathing and arterial hypoxaemia (low oxygen). Chest X-ray shows bilateral diffuse infiltrates. Treatment most often includes mechanical respiratory support. Causes include toxic gas (chlorine, NO2, smoke) exposure, severe metabolic derangement, gastric acid aspiration, pancreatitis, sepsis and trauma. Acronym: ARDS (12 Jul 2000) |
| alkalosis, respiratory | A state due to excess loss of carbon dioxide from the body. (12 Dec 1998) |
| anti-allergic and respiratory system agents | A collective term for drugs used to treat allergic reactions as well as those drugs that produce an effect on the respiratory system. (12 Dec 1998) |
| Bell's respiratory nerve | <anatomy, nerve> Arises from the fifth, sixth, and seventh cervical nerves (roots of brachial plexus), descends the neck behind the brachial plexus, and is distributed to the serratus anterior muscle; it is somewhat unusual in that it courses on the superficial aspect of the muscle is supplies; its paralysis results in "winged scapula". Synonym: nervus thoracicus longus, Bell's respiratory nerve, external respiratory nerve of Bell, posterior thoracic nerve. (05 Mar 2000) |
| bovine respiratory syncytial virus | A pneumovirus causing an emerging disease in young cattle characterised by pneumonia, interstitial pulmonary oedema, and emphysema; sheep are also susceptible to the virus. (05 Mar 2000) |
| rate, respiratory | The number of breaths per minute (or, more formally, the number of movements indicative of inspiration and expiration per unit time). In practice, the respiratory rate is usually determined by counting the number of times the chest rises (or falls) per minute. By whatever means, the aim is to determine if the respirations are normal, abnormally fast (tachypnea), abnormally slow (technically termed bradypnea), or nonexistent (apnea). (12 Dec 1998) |
| Gierke's respiratory bundle | A slender, compact fibre bundle extending longitudinally through the dorsolateral region of the medullary tegmentum, surrounded by the nucleus of the solitary tract, below the obex decussating over the central canal, and descending over some distance into the upper cervical segments of the spinal cord. It is composed of primary sensory fibres that enter with the vagus, glossopharyngeal, and facial nerves, and in part convey information from stretch receptors and chemoreceptors in the walls of the cardiovascular, respiratory, and intestinal tracts; in rostral parts of the tract impulses are generated by the receptor cells of the taste buds in the mucosa of the tongue. Its fibres are distributed to the nucleus of the solitary tract. Synonym: tractus solitarius, fasciculus rotundus, fasciculus solitarius, funiculus solitarius, Gierke's respiratory bundle, Krause's respiratory bundle, round fasciculus, solitary bundle, solitary fasciculus. (05 Mar 2000) |
| region of respiratory mucosa | The area commencing at the vestibule of the nose lined with respiratory mucosa; with the exception of the olfactory mucusa, it includes the entire nasal cavity. Synonym: regio respiratoria tunicae mucosae nasi, respiratory region of tunica mucosa of nose. (05 Mar 2000) |
| virus, respiratory syncytial | A virus that causes mild respiratory infections (colds and coughs) in adults but in young children can produce severe respiratory problems (bronchitis and pneumonia). Effective immunity against rsv requires a continuous solid level of antibodies against the virus. There is particular concern for rsv in premature babies because of their lack of maturity and lack of antibodies. (12 Dec 1998) |