| steroid N-acetylglucosaminyltransferase | <enzyme> Substrate steroids may be replaced by specific cpds Registry number: EC 2.4.1.- (26 Jun 1999) |
|---|---|
| steroid nucleus | tetracyclic steroid nucleus |
| steroid production rate | The total quantity of a given steroid formed in the body, usually expressed as milligrams per day; represents the sum of the glandular secretion of the steroid and extraglandular formation of it from various steroid precursors. (05 Mar 2000) |
| steroid receptor | Family of nuclear transcription factors, most of which are receptors for hormones of the steroid family, for example androgen, oestrogen, glucocorticoid, mineralocorticoid, progesterone, retinoic acid, ecdysone, thyroid hormone and the Drosophila transcription factors knirps, ultraspiracle and seven up. This family contains a conserved domain (the steroid finger motif) containing two C4 type zinc fingers. (18 Nov 1997) |
| steroid secretory rate | The rate of glandular secretion of a given steroid, usually expressed as milligrams per day; does not include any amount of the steroid that might be formed extraglandularly. (05 Mar 2000) |
| steroid sulfatase deficiency | A form of ichthyosis, due to 3-beta-hydroxysteroidsulfate sulfatase deficiency, that appears at birth or in early infancy and affects males; characterised by scaling predominantly on the neck and trunk but not on the palms and soles; histologically, there is hyperkeratosis, a granular layer in the epidermis, and normal epidermal cell turnover. Synonym: steroid sulfatase deficiency. (05 Mar 2000) |
| steroid sulfotransferase | <enzyme> Catalyses the reaction of 3'-phosphoadenylyl sulfate and a phenolic steroid to form adenosine 3',5'-bisphosphate and steroid o-sulfate; has broad specificity Registry number: EC 2.8.2.15 Synonym: phenolic steroid sulfotransferase (26 Jun 1999) |
| steroid ulcer | An ulcer, usually on the leg or foot, developing from a wound in patients undergoing long-term steroid therapy; results from the wound-healing inhibitory effects characteristic of steroids. (05 Mar 2000) |
| steroid withdrawal syndrome | <syndrome> A condition exhibited by persons who previously had been receiving large therapeutic doses of glucocorticoid hormones for long periods of time; pituitary-adrenocortical insufficiency is manifested, particularly during stress, for as long as a year or more thereafter and varying degrees of emotional disturbance may be exhibited. (05 Mar 2000) |
| 17-ketogenic steroid assay test | A colourimetric test, based on the Zimmermann reaction, which indicates metabolites or adrenal and testicular steroids excreted as 17-ketones in the urine; increased values are most striking in adrenocortical tumours, decreased values in Addison's disease or in panhypopituitarism. Synonym: ketogenic corticoids test. (05 Mar 2000) |
| 3 beta-hydroxy-delta 5-C(27)-steroid dehydrogenase | <enzyme> Second enzyme in the sequence that converts cholesterol to bile acids; deficiency leads to chronic liver disease in childhood Registry number: EC 1.1.1.- Synonym: 7 alpha-hydroxycholesterol 3 beta-dehydrogenase, 7-hydroxycholesterol 3-dehydrogenase, 3 beta-hydroxy-delta(5)-c(27)-steroid oxidoreductase, 5-cholestene-3beta,7alpha-diol oxidase (26 Jun 1999) |
| 3-oxo-5 beta-steroid delta 4-dehydrogenase | <enzyme> Do not confuse with EC 1.3.1.23 (cholestenone 5 beta-reductase) which is also steroid 5 beta-reductase in chemline; do not use for enzyme using NADP-see EC 1.3.1.23 and EC 1.3.1.3 Chemical name: 3-oxo-5 beta-steroid delta(4)dehydrogenase Registry number: EC 1.3.99.6 Synonym: steroid 5 beta-reductase, testosterone 5 beta-reductase, 4-ene-5 beta-reductase, delta(4)-3-ketosteroid-5 beta-(acceptor)-reductase, testosterone 5beta-reductase, delta(4)-5beta-reductase, cytosolic 4-ene-reductase (26 Jun 1999) |
| adrenergic receptors | Reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibres of the sympathetic nervous system. Such receptor's can be activated by norepinephrine and/or epinephrine and by various adrenergic drugs; receptor activation results in a change in effector tissue function, such as contraction of arteriolar muscles or relaxation of bronchial muscles; adrenergic receptor's are divided into alpha-receptor's and beta-receptor's, on the basis of their response to various adrenergic activating and blocking agents. Synonym: adrenoceptor, adrenoreceptors. (05 Mar 2000) |
| alpha-adrenergic receptors | Adrenergic receptor's in effector tissues capable of selective activation and blockade by drugs; conceptually derived from the ability of certain agents, such as phenoxybenzamine, to block only some adrenergic receptor's and of other agents, such as methoxamine, to activate only the same adrenergic receptor's. Such receptor's are designated as alpha-receptors. Their activation results in physiological responses such as increased peripheral vascular resistance, mydriasis, and contraction of pilomotor muscles. (05 Mar 2000) |
| ANP clearance receptors | Cell surface proteins that bind atrial natriuretic peptide and ANP fragments without initiating biological action. (05 Mar 2000) |