| conditionally lethal mutant | A viral mutant that can replicate under some (permissive) conditions but not under other (restrictive or nonpermissive) conditions, the parent (wild type) strain being able to replicate under both conditions. See: suppressor-sensitive mutant, temperature-sensitive mutant. Synonym: conditional-lethal mutant. (05 Mar 2000) |
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| constitutive mutant | An organism with a mutation in a regulatory gene, so that the genes which its flawed regulatory product are supposed to suppress become constitutive genes, or impossible to turn off. Thus, the products of the uncontrolled genes are produced to excess. (09 Oct 1997) |
| mutant | <biology, genetics> Refer to an organism, population, gene, or chromosome, etc. Which differs from the corresponding wild type by one or more mutations. (13 Nov 1997) |
| mutant gene | A gene that has been changed from an ancestral type, not necessarily in the current generation. See: mutant, mutation. (05 Mar 2000) |
| homeotic mutant | <molecular biology> A mutant in which one body part, organ or tissue, is transformed into another part normally associated with another segment. Examples are the antennapedia and bithorax mutants of Drosophila. (18 Nov 1997) |
| host range mutant | A mutant of phage or animal virus that grows normally in one of its host cells, but has lost the ability to grow in cells of a second host type. (18 Nov 1997) |
| silent mutant | A mutant that is not phenotypically manifest. Synonym: silent mutant. (05 Mar 2000) |
| suppressor-sensitive mutant | A conditionally lethal, host range, bacteriophage mutant that produces nonsense codons and can replicate only in a host bacterium able to translate the nonsense codon; the mutation's effects are lethal (i.e., prevent replication of the virus) in a bacterium without such a suppressor mechanism. (05 Mar 2000) |
| deficiency mutant | Mutant with a nutritional requirement not present in the wild type organism. Synonym: defective organism, deficiency mutant. (05 Mar 2000) |
| disjunction mutant | Drosophila mutant in which chromosomes are partitioned unequally between daughter cells at meiosis, as a result of nondisjunction. (18 Nov 1997) |
| inactive mutant | A mutant that is not phenotypically manifest. Synonym: silent mutant. (05 Mar 2000) |
| quick-stop mutant | A bacterial mutant that ceases replication immediately when the temperature reaches a certain level. Compare: temperature-sensitive mutant. (05 Mar 2000) |
| temperature-sensitive mutant | A viral mutant that is able to replicate at one portion of a temperature range but not at another, the parent (wild type) strain being able to replicate over the whole temperature range. Compare: cold-sensitive mutant, quick-stop mutant. (05 Mar 2000) |
| uninducible mutant | A mutant that cannot be induced. (05 Mar 2000) |