| human a1-proteinase inhibitor | A glycoprotein that is the major protease inhibitor of human serum, is synthesised in the liver, and is genetically polymorphic due to the presence of over 20 alleles; individuals appropriately homozygous are deficient in a1-trypsin and are predisposed to pulmonary emphysema and juvenile hepatic cirrhosis because of alterations in the amino acid and sialic acid components of the glycoprotein. A1-Antitrypsin also inhibits thrombin. Synonym: a1-trypsin inhibitor, human a1-proteinase inhibitor. (05 Mar 2000) |
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| serine proteinase inhibitors | Exogenous or endogenous compounds which inhibit serine proteinases. (12 Dec 1998) |
| SIV(mac) proteinase | <enzyme> From macaque simian immunodeficiency virus; has 80% homology with hiv protease Registry number: EC 3.4.23.- Synonym: siv mac proteinase, sivmac proteinase siv protease (26 Jun 1999) |
| snake proteinase | <enzyme> Amino acid sequence given in first source Registry number: EC 3.4.21.- Synonym: snake gene product, snake protein, snake protease (26 Jun 1999) |
| SP220K cell surface matrix proteinase | <enzyme> Inactive form has guanidinobenzoatase activity; active form has gelatinolytic activity Registry number: EC 3.4.21.- Synonym: sp220k enzyme (26 Jun 1999) |
| Staphylococcus aureus neutral proteinase | <enzyme> Included in the group of microbial metalloproteinases EC 3.4.24.4; ptrb protein is isolated from E coli; sakstar is recombinant staphylokinase Pharmacological action: fibrinolytic agents Registry number: EC 3.4.24.- Synonym: protease II, staphylokinase, staph aureus protease, staphylococcal protease, E coli protease, ptrb protein, sakstar, (26 Jun 1999) |
| Streptomyces griseus neutral proteinase | <enzyme> Component of pronase; included in the group of microbial metalloproteinases EC 3.4.24.4 Chemical name: streptomyces griseus protease 3 Registry number: EC 3.4.24.- (26 Jun 1999) |
| nsP2 proteinase | <enzyme> Papain-like proteinase from sindbis virus with processes polyprotein precursors; cys-481 and his-558 have been identified as the catalytic dyad Registry number: EC 3.4.22.- Synonym: nonstructural polyprotein 2 proteinase, nsp2 nonstructural proteinase, sindbis virus nsp2 proteinase, nsp2 protein, sindbis virus, nsp2 proteinase, semliki forest virus, sfv nsp2 proteinase (26 Jun 1999) |
| Tc 120 proteinase | <enzyme> Found in cell-free extracts of trypanosoma cruzi epimastigotes; 120 kD protein; hydrolyzes n-z-gly-gly-arg-amc as well as n-z-arg-amc, n-z-phe-arg-amc and n-glutaryl-gly-arg-amc Registry number: EC 3.4.22.- Synonym: alkaline protease (t cruzi) (26 Jun 1999) |
| Thermus aquaticus Rt41A proteinase | <enzyme> Inactive at low temperatures, active at 60 degrees c Registry number: EC 3.4.21.- Synonym: thermus rt41a proteinase, rt41a proteinase (26 Jun 1999) |
| thiol proteinase | Proteases that have an active thiol group. Includes papain and ficin. (18 Nov 1997) |
| easter proteinase | <enzyme> Amino acid sequence of light chain from drosophila has high homology with light chain of tachypleus proclotting enzyme Registry number: EC 3.4.21.- Synonym: easter gene product (26 Jun 1999) |
| Endothia aspartic proteinase | <enzyme> Microbial aspartic proteinase (EC 3.4.23.6, formerly EC 3.4.23.10); from chestnut blight fungus endothia parasitica Registry number: EC 3.4.23.- Synonym: endothiapepsin (26 Jun 1999) |
| Escherichia coli periplasmic proteinase | <enzyme> Included in group of microbial serine proteinases, EC 3.4.21.14 Registry number: EC 3.4.21.- Synonym: E coli protease I, proteinase i (26 Jun 1999) |
| Ycp1 proteinase | <enzyme> The first cysteine proteinase isolated from yeast (saccharomyces cerevisiae); homologous to mammalian bleomycin hydrolase Registry number: EC 3.4.22.- (26 Jun 1999) |